[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100633444":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":21,"centralContacts":25,"locations":31,"responsibleParty":49,"collaborators":20,"id":52,"slug":53,"hasResults":54,"nctId":55,"briefTitle":56,"officialTitle":57,"acronym":20,"eligibilityCriteria":58,"healthyVolunteers":54,"sex":59,"minAge":60,"maxAge":61,"enrollmentInfo":62,"targetDuration":20,"studyType":65,"phases":66,"briefSummary":68,"conditions":69,"keywords":20,"overallStatus":34,"whyStopped":20,"lastUpdateSubmitDate":72,"lastUpdatePostDateStruct":73,"startDateStruct":76,"completionDateStruct":78,"leadSponsor":80,"locationsCount":81},{"fullName":5,"class":6},"Mayo Clinic","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Aerobic and resistance exercise","EXPERIMENTAL","Patients with a history of Spontaneous Coronary Artery Dissection and\u002For Fibromuscular Dysplasia will undergo three exercise tests.",[13],"Behavioral: Aerobic and resistance exercises",[15],{"type":16,"name":17,"description":18,"armGroupLabels":19,"otherNames":20},"BEHAVIORAL","Aerobic and resistance exercises","Subjects will undergo three exercise tests, each separated by at least 48 hours:\n\n* Symptom-limited cardiopulmonary exercise test (CPET): Patients will cycle upright starting at 0W (3 min) before the workload is increased by 10-35W·min-1 in a ramp fashion (like cycling up a progressively steeper hill) until volitional exhaustion for the determination of V̇O2peak and Wpeak\n* Two-stage submaximal constant power exercise test: Following a 5-minute warm-up (10-20 W), participants will cycle in the moderate intensity domain for 25 minutes followed by 25 minutes in the heavy intensity domain.\n* Six different resistance exercises of varying intensities: Participants will perform three sets of six different resistance exercises: chest press; lateral raises; abdominal crunches; planks; leg press; weighted lunges",[9],null,[22],{"name":23,"affiliation":5,"role":24},"Elizabeth H. Dineen, DO","PRINCIPAL_INVESTIGATOR",[26],{"name":27,"role":28,"phone":29,"phoneExt":20,"email":30},"Armia R. Habil, MD","CONTACT","904-953-0859","habil.armia@mayo.edu",[32],{"facility":33,"status":34,"city":35,"state":36,"zip":37,"country":38,"countryCode":39,"cosmosGeoPoint":40,"geoPoint":45,"contacts":46},"Mayo Clinic in Florida","RECRUITING","Jacksonville","Florida","32224","United States","US",{"type":41,"coordinates":42},"Point",[43,44],-81.65565,30.33218,{"lat":44,"lon":43},[47,48],{"name":27,"role":28,"phone":29,"phoneExt":20,"email":30},{"name":23,"role":24,"phone":20,"phoneExt":20,"email":20},{"type":24,"investigatorFullName":50,"investigatorTitle":51,"investigatorAffiliation":5,"oldNameTitle":20,"oldOrganization":20},"Elizabeth H. Dineen","Principal Investigator","100633444","a-study-of-exercise-in-patients-with-spontaneous-coronary-artery-dissection-and-fibromuscular-dysplasia-100633444",false,"NCT07526766","A Study Of Exercise In Patients With Spontaneous Coronary Artery Dissection And Fibromuscular Dysplasia","Cardiopulmonary, Hemodynamic, And Symptom Responses To Aerobic And Resistance Exercise In Patients With Spontaneous Coronary Artery Dissection And Fibromuscular Dysplasia: A Single-center, Single-arm Prospective Clinical Trial.","Inclusion criteria:\n\n* History of Spontaneous Coronary Artery Dissection (SCAD) and\u002For Fibromuscular Dysplasia (FMD), ≥2 months post-event, and free from chest pain.\n* Able to provide written informed consent\n\nExclusion criteria:\n\n* Individuals who are clinically obese (BMI ≥36) and\u002For who suffer from musculoskeletal or other conditions that would limit exercise participation.\n* Individuals who are deemed medically unstable\n* Participants who are unable to comply with study requirements.\n* Pregnancy","ALL","21 Years","65 Years",{"count":63,"type":64},28,"ESTIMATED","INTERVENTIONAL",[67],"NA","The purpose of this study is to assess the cardiopulmonary, hemodynamic, and symptom responses to acute bouts of varying intensity aerobic and resistance exercise in people with Spontaneous Coronary Artery Dissection (SCAD) and\u002For Fibromuscular Dysplasia (FMD).",[70,71],"Fibromuscular Dysplasia","Spontaneous Coronary Artery Dissection","2026-04-06",{"date":74,"type":75},"2026-04-13","ACTUAL",{"date":77,"type":64},"2026-04-01",{"date":79,"type":64},"2027-07-01",{"name":5,"class":6},1]