[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100638938":3},{"organization":4,"armGroups":7,"interventions":15,"overallOfficials":29,"centralContacts":33,"locations":42,"responsibleParty":125,"collaborators":127,"id":131,"slug":132,"hasResults":133,"nctId":134,"briefTitle":135,"officialTitle":136,"acronym":10,"eligibilityCriteria":137,"healthyVolunteers":133,"sex":138,"minAge":139,"maxAge":10,"enrollmentInfo":140,"targetDuration":10,"studyType":143,"phases":10,"briefSummary":144,"conditions":145,"keywords":148,"overallStatus":45,"whyStopped":10,"lastUpdateSubmitDate":150,"lastUpdatePostDateStruct":151,"startDateStruct":154,"completionDateStruct":156,"leadSponsor":158,"locationsCount":159},{"fullName":5,"class":6},"Memorial Sloan Kettering Cancer Center","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Participants at high risk for pancreas ductal adenocarcinoma",null,"Participants will be high-risk individuals enrolled in the Memorial Sloan Kettering Pancreatic Tumor Registry",[13,14],"Diagnostic Test: MRI","Diagnostic Test: Endoscopic ultrasound",[16,23],{"type":17,"name":18,"description":19,"armGroupLabels":20,"otherNames":21},"DIAGNOSTIC_TEST","MRI","Participants will undergo a single MRI of the abdomen without contrast",[9],[22],"Magnetic Resonance CholangioPancreatography, MRP",{"type":17,"name":24,"description":25,"armGroupLabels":26,"otherNames":27},"Endoscopic ultrasound","EUS will be scheduled the same day or within 2 weeks prior to MRP",[9],[28],"EUS",[30],{"name":31,"affiliation":5,"role":32},"Richard Kinh Gian Do, MD, PhD","PRINCIPAL_INVESTIGATOR",[34,38],{"name":31,"role":35,"phone":36,"phoneExt":10,"email":37},"CONTACT","212-639-8591","dok@mskcc.org",{"name":39,"role":35,"phone":40,"phoneExt":10,"email":41},"Mengmeng Du, ScD","646-227-3495","dumeng@mskcc.org",[43,59,70,81,93,104,114],{"facility":44,"status":45,"city":46,"state":47,"zip":48,"country":49,"countryCode":50,"cosmosGeoPoint":51,"geoPoint":56,"contacts":57},"Memorial Sloan Kettering Basking Ridge (Consent Only)","RECRUITING","Basking Ridge","New Jersey","07920","United States","US",{"type":52,"coordinates":53},"Point",[54,55],-74.54932,40.70621,{"lat":55,"lon":54},[58],{"name":31,"role":35,"phone":36,"phoneExt":10,"email":10},{"facility":60,"status":45,"city":61,"state":47,"zip":62,"country":49,"countryCode":50,"cosmosGeoPoint":63,"geoPoint":67,"contacts":68},"Memorial Sloan Kettering Monmouth (Consent only)","Middletown","07748",{"type":52,"coordinates":64},[65,66],-74.11709,40.39428,{"lat":66,"lon":65},[69],{"name":31,"role":35,"phone":36,"phoneExt":10,"email":10},{"facility":71,"status":45,"city":72,"state":47,"zip":73,"country":49,"countryCode":50,"cosmosGeoPoint":74,"geoPoint":78,"contacts":79},"Memorial Sloan Kettering Bergen (Consent Only)","Montvale","07645",{"type":52,"coordinates":75},[76,77],-74.02292,41.04676,{"lat":77,"lon":76},[80],{"name":31,"role":35,"phone":36,"phoneExt":10,"email":10},{"facility":82,"status":45,"city":83,"state":84,"zip":85,"country":49,"countryCode":50,"cosmosGeoPoint":86,"geoPoint":90,"contacts":91},"Memorial Sloan Kettering Suffolk-Commack (Consent only)","Commack","New York","11725",{"type":52,"coordinates":87},[88,89],-73.29289,40.84288,{"lat":89,"lon":88},[92],{"name":31,"role":35,"phone":36,"phoneExt":10,"email":10},{"facility":94,"status":45,"city":95,"state":84,"zip":96,"country":49,"countryCode":50,"cosmosGeoPoint":97,"geoPoint":101,"contacts":102},"Memorial Sloan Kettering Westchester (Consent only)","Harrison","10604",{"type":52,"coordinates":98},[99,100],-73.71263,40.96899,{"lat":100,"lon":99},[103],{"name":31,"role":35,"phone":36,"phoneExt":10,"email":10},{"facility":105,"status":45,"city":84,"state":84,"zip":106,"country":49,"countryCode":50,"cosmosGeoPoint":107,"geoPoint":111,"contacts":112},"Memorial Sloan Kettering Cancer Center (All Protocol Activites)","10065",{"type":52,"coordinates":108},[109,110],-74.00597,40.71427,{"lat":110,"lon":109},[113],{"name":31,"role":35,"phone":36,"phoneExt":10,"email":10},{"facility":115,"status":45,"city":116,"state":84,"zip":117,"country":49,"countryCode":50,"cosmosGeoPoint":118,"geoPoint":122,"contacts":123},"Memorial Sloan Kettering Nassau (Consent Only)","Uniondale","11553",{"type":52,"coordinates":119},[120,121],-73.59291,40.70038,{"lat":121,"lon":120},[124],{"name":31,"role":35,"phone":36,"phoneExt":10,"email":10},{"type":126,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR",[128],{"name":129,"class":130},"National Institutes of Health (NIH)","NIH","100638938","a-study-of-magnetic-resonance-imaging-of-the-pancreas-for-cancer-screening-100638938",false,"NCT07612046","A Study of Magnetic Resonance Imaging of the Pancreas for Cancer Screening","Pilot Study of a Dedicated MR of the Pancreas: Improving Screening for Patients at High Risk for Pancreas Cancer","Inclusion Criteria:\n\n* Two first-degree relatives with pancreas cancer, one being a first-degree relative to the individual\n* Pathogenic mutation in APC, BRCA1, MLH1, MSH2, MSH6, PMS2, EPCAM, PALB2, or TP53 and a first\u002Fsecond-degree relative with pancreas cancer\n* Pathogenic mutation in CDKN2A\u002Fp16, STK11, PRSS1, SPINK1\u002FPST1, CTRC, CPA1, ATM, or BRCA2\n* Meets surveillance age eligibility, which is typically age 50, or 10 years earlier than the youngest relative with pancreas cancer. For individuals with certain gene mutations, this can be earlier. All participants must be aged 21+\n\nFor this pilot MRP study, we will additionally apply the following Criteria:\n\n* Consents to follow-up contact\n* US residents\n* Completed MRI with MRCP with no actionable findings related to the pancreas (e.g. a pancreatic mass)\n* No metallic artifacts covering the pancreas on prior MRCP\n* Scheduled for endoscopic ultrasound\n* No new contraindications for MRI (e.g. new MR unsafe device)\n* No history of claustrophobia or use of anxiolytic on prior MRI\n* No history of abdominal surgery that may affect interpretation of either EUS or MR\n* No medical conditions that confers increased and\u002For unacceptable risk for anesthesia\n\nWe will recruit surveillance participants who had at least one prior MRCP in the last 3 years. They must also undergo a same-day EUS procedure as part of their surveillance. Nearly all active cohort participants have had at least one recent MRCP and, on average, our Registry gastroenterologist Dr. Rolston performs EUS in \\~260 surveillance participants per year. Accordingly, it is highly feasible to recruit more than 79 participants in the grant period, and recruitment is constrained by budget.\n\n* Documentation of Disease\n\n  o No pathologic confirmation of disease is necessary\n* Definition of Disease N\u002FA\n* Not Pregnant and Not Nursing\n* Required Organ Function N\u002FA\n\nExclusion Criteria:\n\n\\-","ALL","18 Years",{"count":141,"type":142},79,"ESTIMATED","OBSERVATIONAL","The purpose of this study is to develop a dedicated MRI scan of the pancreas (MRP) to better detect pancreatic cancer in people who are at a high risk for pancreatic cancer.",[146,147],"Pancreatic Cancer","Pancreas Cancer",[146,147,5,149],"26-174","2026-05-21",{"date":152,"type":153},"2026-05-28","ACTUAL",{"date":155,"type":153},"2026-05-20",{"date":157,"type":142},"2028-05-20",{"name":5,"class":6},7]