[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100606665":3},{"organization":4,"armGroups":7,"interventions":18,"overallOfficials":24,"centralContacts":28,"locations":34,"responsibleParty":52,"collaborators":55,"id":59,"slug":60,"hasResults":61,"nctId":62,"briefTitle":63,"officialTitle":64,"acronym":10,"eligibilityCriteria":65,"healthyVolunteers":66,"sex":67,"minAge":68,"maxAge":10,"enrollmentInfo":69,"targetDuration":10,"studyType":72,"phases":10,"briefSummary":73,"conditions":74,"keywords":10,"overallStatus":36,"whyStopped":10,"lastUpdateSubmitDate":76,"lastUpdatePostDateStruct":77,"startDateStruct":80,"completionDateStruct":82,"leadSponsor":84,"locationsCount":85},{"fullName":5,"class":6},"Mayo Clinic","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Spontaneous coronary artery dissection (SCAD)",null,"Subject has a history of spontaneous coronary artery dissection (SCAD)",[13],"Procedure: Stress Echocardiography with Contrast",{"label":15,"type":10,"description":16,"interventionNames":17},"Healthy Subjects","Subjects are healthy with no significant medical history",[13],[19],{"type":20,"name":21,"description":22,"armGroupLabels":23,"otherNames":10},"PROCEDURE","Stress Echocardiography with Contrast","Stress Echocardiography with Contrast will be used to assess heart function and blood flow response to stressors.",[15,9],[25],{"name":26,"affiliation":5,"role":27},"Marysia Tweet, M.D., M.S.","PRINCIPAL_INVESTIGATOR",[29],{"name":30,"role":31,"phone":32,"phoneExt":10,"email":33},"Pamela Engrav","CONTACT","507-255-6938","engrav.pamela@mayo.edu",[35],{"facility":5,"status":36,"city":37,"state":38,"zip":39,"country":40,"countryCode":41,"cosmosGeoPoint":42,"geoPoint":47,"contacts":48},"RECRUITING","Rochester","Minnesota","55905","United States","US",{"type":43,"coordinates":44},"Point",[45,46],-92.4699,44.02163,{"lat":46,"lon":45},[49,50],{"name":30,"role":31,"phone":32,"phoneExt":10,"email":33},{"name":51,"role":27,"phone":10,"phoneExt":10,"email":10},"Marysia S Tweet, M.D., M.S.",{"type":27,"investigatorFullName":53,"investigatorTitle":54,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"Marysia Tweet","Principal Investigator",[56],{"name":57,"class":58},"National Heart, Lung, and Blood Institute (NHLBI)","NIH","100606665","a-study-of-scad-using-stress-contrast-echocardiography-100606665",false,"NCT07178509","A Study of SCAD Using Stress Contrast Echocardiography","Myocardial Perfusion in Spontaneous Coronary Artery Dissection Using Stress Contrast Echocardiography","Inclusion Criteria:\n\n* Adult \\>18 years old\n* Patient has a history of spontaneous coronary artery dissection (SCAD) OR patient is healthy with no significant medical history\n\nExclusion Criteria:\n\n* Unable to give consent\n* Allergic or have a history of adverse reaction to dobutamine, the Definity® ultrasound enhancing agent, or atropine.\n* Has a known or suspected hypersensitivity to perflutren and therefore cannot be given Definity®.\n* Pregnant.\n* Unable to interrupt breastfeeding.\n* Within 3 months of a heart attack.\n* Severe aortic stenosis.\n* Severe, uncontrolled hypertension (\\>200\u002F110 mmHg at baseline).",true,"ALL","18 Years",{"count":70,"type":71},50,"ESTIMATED","OBSERVATIONAL","This study aims to fill knowledge gaps regarding microvascular perfusion and pressor response to stress among patients with history of spontaneous coronary artery dissection (SCAD) using stress contrast echocardiography.",[75],"Spontaneous Coronary Artery Dissection","2026-01-06",{"date":78,"type":79},"2026-01-07","ACTUAL",{"date":81,"type":79},"2025-11-25",{"date":83,"type":71},"2027-09",{"name":5,"class":6},1]