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Misericordia\"","Udine","33100",{"type":43,"coordinates":633},[634,635],13.23715,46.0693,{"lat":635,"lon":634},{"facility":638,"status":37,"city":639,"state":10,"zip":640,"country":433,"countryCode":434,"cosmosGeoPoint":641,"geoPoint":645,"contacts":10},"Azienda ULSS 8 Berica - Ospedale San Bortolo","Vicenza","36100",{"type":43,"coordinates":642},[643,644],11.5475,45.54672,{"lat":644,"lon":643},{"facility":647,"status":37,"city":648,"state":10,"zip":649,"country":650,"countryCode":651,"cosmosGeoPoint":652,"geoPoint":656,"contacts":10},"ULS Almada-Seixal","Almada","2805-267","Portugal","PT",{"type":43,"coordinates":653},[654,655],-9.1569,38.67902,{"lat":655,"lon":654},{"facility":658,"status":37,"city":659,"state":10,"zip":660,"country":650,"countryCode":651,"cosmosGeoPoint":661,"geoPoint":665,"contacts":10},"USL Braga","Braga","4710-243",{"type":43,"coordinates":662},[663,664],-8.42311,41.5514,{"lat":664,"lon":663},{"facility":667,"status":37,"city":668,"state":10,"zip":669,"country":650,"countryCode":651,"cosmosGeoPoint":670,"geoPoint":674,"contacts":10},"ULS Coimbra","Coimbra","3004-561",{"type":43,"coordinates":671},[672,673],-8.41996,40.20686,{"lat":673,"lon":672},{"facility":676,"status":37,"city":677,"state":10,"zip":678,"country":650,"countryCode":651,"cosmosGeoPoint":679,"geoPoint":683,"contacts":10},"IPO Lisboa","Lisbon","1099-023",{"type":43,"coordinates":680},[681,682],-9.1498,38.72509,{"lat":682,"lon":681},{"facility":685,"status":37,"city":677,"state":10,"zip":686,"country":650,"countryCode":651,"cosmosGeoPoint":687,"geoPoint":689,"contacts":10},"CC Champalimaud","1400-038",{"type":43,"coordinates":688},[681,682],{"lat":682,"lon":681},{"facility":691,"status":37,"city":677,"state":10,"zip":692,"country":650,"countryCode":651,"cosmosGeoPoint":693,"geoPoint":695,"contacts":10},"Hospital da Luz","1500-650",{"type":43,"coordinates":694},[681,682],{"lat":682,"lon":681},{"facility":697,"status":37,"city":698,"state":10,"zip":699,"country":650,"countryCode":651,"cosmosGeoPoint":700,"geoPoint":704,"contacts":10},"ULS Santo António","Porto","4050-342",{"type":43,"coordinates":701},[702,703],-8.61097,41.1485,{"lat":703,"lon":702},{"facility":706,"status":37,"city":706,"state":10,"zip":707,"country":650,"countryCode":651,"cosmosGeoPoint":708,"geoPoint":712,"contacts":10},"Vila Real","5000-508",{"type":43,"coordinates":709},[710,711],-7.7432,41.3001,{"lat":711,"lon":710},{"type":714,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR","100515571","a-study-of-trastuzumab-deruxtecan-for-patients-with-advanced-her2-positive-gastric-or-gastroesophageal-junction-adenocarcinoma-who-have-received-a-prior-trastuzumab-based-regimen-accompanied-by-a-disease-registry-of-patients-treated-with-conventional-therapies-prosperity-100515571",false,"NCT05993234","A Study of Trastuzumab DeRuxtecan for Patients With Advanced HER2-pOsitive GaStric or GastroesoPhageal Junction AdEnocarcinoma Who Have Received a PrIor Trastuzumab-based Regimen Accompanied by a Disease RegistrY of Patients Treated With Conventional Therapies (PROSPERITY)","A Prospective Non-interventional Study (NIS) of Trastuzumab DeRuxtecan (T-DXd) for Adult Patients With Advanced HER2-pOsitive GaStric or GastroesoPhageal Junction (GEJ) AdEnocarcinoma Who Have Received a PrIor Trastuzumab-based Regimen, Accompanied by a Disease RegistrY of Patients Treated With Conventional Therapies in a Real-world Setting in Europe (PROSPERITY)","Inclusion Criteria:\n\n* Male or female adult patient (age ≥ 18 years) with HER2 + advanced gastric or GEJ adenocarcinoma who have received a prior trastuzumab based regimen\n* Histological or cytological confirmed diagnosis of advanced HER2 positive gastric cancer or GEJ\n* Documented HER2 + status (archival sample or recent sample prior 2L therapy)\n* Decision to newly initiate monotherapy T-DXd or conventional therapies per SMPC according to the physician's choice\n* Written dated and signed Informed Consent (ICF) to participate in the study\n\nExclusion Criteria:\n\n* Patients who at time of data collection for this study are participating in or have participated in an interventional study that remains blinded\n* Pregnancy or breastfeeding\n\nNo specific exclusion criteria are defined, as patients will be treated according to the proposed indication statements in the SmPC.","ALL","18 Years",{"count":725,"type":726},257,"ESTIMATED","2 Years","OBSERVATIONAL","Trastuzumab deruxtecan (T-DXD) as monotherapy is indicated for the treatment of adult patients with advanced HER2-positive advanced gastric or gastroesophageal junction (GEJ) adenocarcinoma who have received a prior trastuzumab-based regimen.\n\nThis study will assess the effectiveness of T-DXd, patient demographic and clinical characteristics, and treatment patterns in patients with advanced HER2-positive advanced gastric or GEJ adenocarcinoma.",[731,732],"HER2-positive Advanced Gastric Cancer","HER2-positive Gastroesophageal Junction Adenocarcinoma",[731,732,734,735,22],"Trastuzumab Deruxtecan","Conventional therapy","2026-05-05",{"date":738,"type":739},"2026-05-08","ACTUAL",{"date":741,"type":739},"2023-12-05",{"date":743,"type":726},"2027-09-01",{"name":26,"class":6},76]