[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100570492":3},{"organization":4,"armGroups":7,"interventions":21,"overallOfficials":10,"centralContacts":27,"locations":10,"responsibleParty":37,"collaborators":10,"id":41,"slug":42,"hasResults":43,"nctId":44,"briefTitle":45,"officialTitle":46,"acronym":10,"eligibilityCriteria":47,"healthyVolunteers":43,"sex":48,"minAge":49,"maxAge":50,"enrollmentInfo":51,"targetDuration":10,"studyType":54,"phases":10,"briefSummary":55,"conditions":56,"keywords":59,"overallStatus":61,"whyStopped":10,"lastUpdateSubmitDate":62,"lastUpdatePostDateStruct":63,"startDateStruct":66,"completionDateStruct":68,"leadSponsor":70,"locationsCount":10},{"fullName":5,"class":6},"Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine","OTHER",[8,12,17],{"label":9,"type":10,"description":11,"interventionNames":10},"Conservative treatment group",null,"Non-steroidal anti-inflammatory and analgesic drugs",{"label":13,"type":10,"description":14,"interventionNames":15},"Arthroscopic partial meniscectomy group","Arthroscopically, the damaged free meniscus is trimmed, ground, and partially resected;",[16],"Procedure: Arthroscopic meniscus surgery",{"label":18,"type":10,"description":19,"interventionNames":20},"Arthroscopic meniscus suture repair group","Arthroscopic download of the posterior meniscus root injury, placement of sutures through the bone tunnel to fix the meniscus, and then cutting it with a knot to complete the meniscus suture repair.",[16],[22],{"type":23,"name":24,"description":25,"armGroupLabels":26,"otherNames":10},"PROCEDURE","Arthroscopic meniscus surgery","Comparison of the incidence of osteoarthritis with conservative treatment as well as arthroscopic partial resection as well as arthroscopic repair surgery for a condition known as posterior meniscus root injury.",[18,13],[28,33],{"name":29,"role":30,"phone":31,"phoneExt":10,"email":32},"Haifeng Zhang, Ph.D","CONTACT","86-15216619279","haifeng.zhang@shgh.cn",{"name":34,"role":30,"phone":35,"phoneExt":10,"email":36},"Yinxian Yu, Ph.D","86-1502179842","eastpool@sjtu.edu.cn",{"type":38,"investigatorFullName":39,"investigatorTitle":40,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"PRINCIPAL_INVESTIGATOR","Yinxian Yu","Associate Professor","100570492","a-study-on-different-treatments-for-knee-osteoarthritis-caused-by-damaged-roots-of-the-medial-meniscus-100570492",false,"NCT06707948","A Study on Different Treatments for Knee Osteoarthritis Caused by Damaged Roots of the Medial Meniscus.","Comparison of Different Treatment Strategies for Root Injury Behind the Medial Meniscus to Delay the Progression of Knee Osteoarthritis: a Prospective Cohort Study","Inclusion Criteria:\n\n1. Clinical diagnosis of posterior root tear of the medial meniscus;\n2. Patients with K-L classification ≤ grade II;\n3. The age range of 50-65 years old;\n4. International Cartilage Repair Society (ICRS) Modified Magnetic Resonance Imaging Grading System ≤ Grade 2;\n5. International Cartilage Repair Society (ICRS) arthroscopic grading system ≤ grade 2;\n6. Knee joint mobility ≥90°;\n7. Inversion deformity ≤10°;\n8. Must be able to complete follow-up MRI within 2 years after knee meniscus surgery;\n9. Must be able to complete clinical data;\n\nExclusion Criteria:\n\n1. Can not participate in this study;\n2. Patients with concomitant meniscal injuries elsewhere;\n3. knee joint infection disease;\n4. Osteoporosis disease;\n5. Patients with previous history of knee surgery;\n6. Knee joint instability disease;\n7. Severe KOA disease;\n8. Can not cooperate with MRI detection;\n9. Cannot tolerate the surgery;\n10. Those who cannot tolerate the arthroscopic knee surgery;\n11. Neuromuscular system pathology disease;","ALL","50 Years","65 Years",{"count":52,"type":53},69,"ESTIMATED","OBSERVATIONAL","Medial meniscus posterior root tears (MMPRT) account for 20% or more of all meniscus tears, but the diagnosis and treatment of this condition continues to plague the general population due to the complexity of the diagnosis and uncertainty of the treatment. Early as well as timely diagnosis and treatment is one of the effective ways to avoid accelerated knee degeneration. Based on this study, our team is going to conduct a clinical study on posterior medial meniscus tear, combining Magnetic Resonance Imaging(MRI) to dynamically assess the changes of meniscus and articular cartilage surface after the injury, and selecting a specific patient group to carry out different therapeutic interventions, which mainly include conservative treatment, partial meniscectomy, and meniscal repair, in order to clarify the effects of different treatment modalities on the articular cartilage after the posterior meniscus tear, and to help to delay the degeneration of knee joints. This is to clarify the effects of different treatment modalities on the articular cartilage after posterior medial meniscus tears and to provide appropriate advice for delaying the progression of osteoarthritis of the knee.",[57,58],"Osteoarthritis","Meniscus Lesion",[60],"posterior meniscus root lesion;Osteoarthrotis","NOT_YET_RECRUITING","2024-11-26",{"date":64,"type":65},"2024-11-27","ACTUAL",{"date":67,"type":53},"2024-11-30",{"date":69,"type":53},"2027-12-15",{"name":5,"class":6}]