[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100595103":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":11,"centralContacts":29,"locations":11,"responsibleParty":35,"collaborators":37,"id":51,"slug":52,"hasResults":53,"nctId":54,"briefTitle":55,"officialTitle":56,"acronym":11,"eligibilityCriteria":57,"healthyVolunteers":53,"sex":58,"minAge":59,"maxAge":60,"enrollmentInfo":61,"targetDuration":11,"studyType":64,"phases":65,"briefSummary":67,"conditions":68,"keywords":73,"overallStatus":78,"whyStopped":11,"lastUpdateSubmitDate":79,"lastUpdatePostDateStruct":80,"startDateStruct":83,"completionDateStruct":85,"leadSponsor":87,"locationsCount":11},{"fullName":5,"class":6},"The Affiliated Hospital of Qingdao University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Control group","ACTIVE_COMPARATOR",null,[13],"Device: Conventional OLIF cage",{"label":15,"type":16,"description":11,"interventionNames":17},"Experimental group","EXPERIMENTAL",[18],"Device: Expandable OLIF cage with posterior bone grafting",[20,25],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":11},"DEVICE","Expandable OLIF cage with posterior bone grafting","This intervention involves the use of a novel expandable OLIF cage that allows intraoperative height adjustment and posterior bone grafting through a dedicated channel. The device is designed to restore intervertebral height and lumbar lordosis while minimizing endplate injury. Bone grafts (autologous or synthetic) are delivered after expansion to enhance fusion. This design aims to reduce cage subsidence, improve fusion rates, and simplify the surgical workflow compared to conventional OLIF cages with fixed heights.",[15],{"type":21,"name":26,"description":27,"armGroupLabels":28,"otherNames":11},"Conventional OLIF cage","Participants in the control group will undergo oblique lateral interbody fusion (OLIF) using a standard non-expandable interbody fusion cage. The cage has a fixed height and is inserted via the retroperitoneal approach. Bone grafts are packed into the cage prior to insertion through the anterior or lateral window. This represents the current standard practice for OLIF procedures and does not allow intraoperative height adjustment or posterior graft delivery. The procedure follows conventional OLIF surgical protocols without additional design modifications.",[9],[30],{"name":31,"role":32,"phone":33,"phoneExt":11,"email":34},"Xuexiao XX Ma","CONTACT","+86 18661807895","maxuexiao7895@163.com",{"type":36,"investigatorFullName":11,"investigatorTitle":11,"investigatorAffiliation":11,"oldNameTitle":11,"oldOrganization":11},"SPONSOR",[38,40,42,44,47,49],{"name":39,"class":6},"The First Affiliated Hospital of Zhengzhou University",{"name":41,"class":6},"Peking University People's Hospital",{"name":43,"class":6},"Shanghai Jiao Tong University Affiliated Sixth People's Hospital",{"name":45,"class":46},"Jinan Hospital, Xuanwu Hospital, Capital Medical University","UNKNOWN",{"name":48,"class":6},"Union Hospital, Tongji Medical College, Huazhong University of Science and Technology",{"name":50,"class":46},"Shanghai changzheng hospital, Naval Medical University","100595103","a-study-on-the-clinical-use-of-a-new-expandable-olif-cage-with-posterior-bone-grafting-in-lumbar-spine-surgery-100595103",false,"NCT07028099","A Study on the Clinical Use of a New Expandable OLIF Cage With Posterior Bone Grafting in Lumbar Spine Surgery","Multi-Center Randomized Controlled Clinical Study on the Application of a Novel Expandable Posterior Bone Grafting OLIF Cage","Inclusion Criteria:1: Age between 40 and 80 years (inclusive)\n\n2: Clinically diagnosed with lumbar spondylolisthesis or lumbar spinal stenosis\n\n3: Confirmed single-level lumbar degenerative disease\n\n4: Affected level located at L2\u002F3, L3\u002F4, or L4\u002F5\n\n5: Failure of conservative treatment for at least 6 months\n\nExclusion Criteria:1: Patients requiring direct decompression of the spinal canal\n\n2: History of prior lumbar or retroperitoneal surgery\n\n3: Abnormal anatomy between the iliac vascular sheath and the psoas major muscle\n\n4: Presence of active infection or other significant systemic diseases\n\n5: Inability to complete surgical treatment or comply with follow-up due to various limitations\n\n\\-","ALL","40 Years","80 Years",{"count":62,"type":63},340,"ESTIMATED","INTERVENTIONAL",[66],"NA","This clinical trial aims to evaluate the safety and effectiveness of a novel expandable OLIF (Oblique Lateral Interbody Fusion) cage with posterior bone grafting in patients with lumbar degenerative diseases. OLIF is a minimally invasive spinal surgery technique that restores intervertebral height and relieves nerve compression by placing a cage into the disc space.\n\nThe new device allows surgeons to adjust the height of the cage during surgery and deliver bone grafts through a special channel after expansion. This study compares the outcomes of patients receiving the new cage versus those treated with a conventional OLIF cage.\n\nThe trial will assess pain relief, functional improvement, spinal stability, fusion success, and potential complications. Radiological images and patient-reported scores (like VAS and ODI) will be collected over 12 months. The study includes patients aged 40 to 80 with single-level lumbar spine disease who have not improved after at least 6 months of conservative treatment.\n\nThis study will help determine whether the new expandable cage offers clinical advantages and better long-term outcomes for patients undergoing OLIF surgery.",[69,70,71,72],"Lumbar Spondylolisthesis","Degenerative Lumbar Scoliosis","Lumbar Disc Herniation","Lumbar Spinal Stenosis",[74,75,76,77],"Expandable OLIF Cage","Minimally Invasive Spine Surgery","Prospective Multicenter Randomized Controlled Trial","Degenerative Lumbar Disease","NOT_YET_RECRUITING","2025-06-17",{"date":81,"type":82},"2025-06-19","ACTUAL",{"date":84,"type":63},"2025-06-10",{"date":86,"type":63},"2027-05-31",{"name":5,"class":6}]