[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100550487":3},{"organization":4,"armGroups":7,"interventions":17,"overallOfficials":10,"centralContacts":23,"locations":29,"responsibleParty":51,"collaborators":10,"id":53,"slug":54,"hasResults":55,"nctId":56,"briefTitle":57,"officialTitle":58,"acronym":10,"eligibilityCriteria":59,"healthyVolunteers":60,"sex":61,"minAge":62,"maxAge":63,"enrollmentInfo":64,"targetDuration":10,"studyType":67,"phases":10,"briefSummary":68,"conditions":69,"keywords":10,"overallStatus":32,"whyStopped":10,"lastUpdateSubmitDate":72,"lastUpdatePostDateStruct":73,"startDateStruct":76,"completionDateStruct":78,"leadSponsor":80,"locationsCount":81},{"fullName":5,"class":6},"Zhujiang Hospital","OTHER",[8,12],{"label":9,"type":10,"description":11,"interventionNames":10},"No aneurysm wall enhancement",null,"The aneurysm wall did not show enhanced signal on high-resolution magnetic resonance imaging.",{"label":13,"type":10,"description":14,"interventionNames":15},"Aneurysm wall enhancement","The aneurysm wall shows enhanced signal on high-resolution magnetic resonance imaging.",[16],"Behavioral: smoke",[18],{"type":19,"name":20,"description":21,"armGroupLabels":22,"otherNames":10},"BEHAVIORAL","smoke","cotinine detection",[13],[24],{"name":25,"role":26,"phone":27,"phoneExt":10,"email":28},"Xin Feng, MD","CONTACT","+8613681134001","13681134001@163.com",[30],{"facility":31,"status":32,"city":33,"state":34,"zip":35,"country":36,"countryCode":37,"cosmosGeoPoint":38,"geoPoint":43,"contacts":44},"Zhujiang Hospital, Southern Medical University","RECRUITING","Guangzhou","Guangdong","528400","China","CN",{"type":39,"coordinates":40},"Point",[41,42],113.25,23.11667,{"lat":42,"lon":41},[45,47],{"name":46,"role":26,"phone":27,"phoneExt":10,"email":28},"Feng Xin, MD",{"name":48,"role":26,"phone":49,"phoneExt":10,"email":50},"Wen Zhuohua, MD","+8615622311746","810107327@qq.com",{"type":52,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR","100550487","a-study-on-the-correlation-between-cotinine-levels-and-aneurysm-wall-enhancement-on-hrmri-100550487",false,"NCT06447714","A Study on the Correlation Between Cotinine Levels and Aneurysm Wall Enhancement on HRMRI.","A Prospective Cohort Study on the Correlation Between Patient Cotinine Levels and Intracranial Unruptured Aneurysm Wall Enhancement Based on High-resolution Magnetic Resonance Imaging","Inclusion Criteria:\n\n* Age 18-75 years old, male or infertile female;\n* Diagnosed as IA (intracranial aneurysm) through CTA, MRA, or DSA; And it is suitable for endovascular intervention treatment\n* The patient and\u002For their legal representative or guardian fully understand the research purpose, voluntarily participate and sign informed consent Books;\n* Patients willing to cooperate with high-resolution magnetic resonance imaging.\n* Patients willing to follow up and evaluate according to clinical research protocol requirements\n\nExclusion Criteria:\n\n* AVM (arteriovenous malformation), Moyamoya disease, or DAVF (dural arteriovenous fistula) related aneurysms;\n* Patients with contraindications for high-resolution magnetic resonance imaging;\n* Participants in clinical trials of other drugs or medical devices;\n* Patients with severe underlying diseases and extremely poor clinical conditions who cannot tolerate general anesthesia surgery;\n* Patients with poor compliance and inability to cooperate with follow-up;\n* Possible or clear history of severe allergy to contrast agents;\n* Patients with a life expectancy of less than 2 years;\n* Women who are breastfeeding and preparing for pregnancy during the study period",true,"ALL","18 Years","75 Years",{"count":65,"type":66},450,"ESTIMATED","OBSERVATIONAL","This study aims to collect clinical, laboratory, and imaging data from patients with unruptured intracranial aneurysms, and collect blood or urine samples for cotinine testing. The enrolled patients underwent high-resolution magnetic resonance angiography to detect whether the intracranial aneurysm wall was enhanced and classify the degree of enhancement. The purpose is to study the correlation between arterial aneurysm wall enhancement and cotinine levels",[70,71],"Cotinine Levels","Arterial Aneurysm Wall Enhancement on HRMRI","2025-07-15",{"date":74,"type":75},"2025-07-18","ACTUAL",{"date":77,"type":75},"2022-09-01",{"date":79,"type":66},"2027-03-01",{"name":5,"class":6},1]