[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100530954":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":25,"centralContacts":29,"locations":38,"responsibleParty":57,"collaborators":25,"id":61,"slug":62,"hasResults":63,"nctId":64,"briefTitle":65,"officialTitle":65,"acronym":25,"eligibilityCriteria":66,"healthyVolunteers":63,"sex":67,"minAge":25,"maxAge":25,"enrollmentInfo":68,"targetDuration":25,"studyType":71,"phases":72,"briefSummary":74,"conditions":75,"keywords":77,"overallStatus":41,"whyStopped":25,"lastUpdateSubmitDate":82,"lastUpdatePostDateStruct":83,"startDateStruct":86,"completionDateStruct":88,"leadSponsor":90,"locationsCount":91},{"fullName":5,"class":6},"Karolinska Institutet","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Platelet rich plasma (PRP)","ACTIVE_COMPARATOR","High-concentration PRP injection PRP injection (0,6-1ml). Arthrex ACPmax system.",[13],"Procedure: Platelet rich plasma (PRP)",{"label":15,"type":16,"description":17,"interventionNames":18},"Placebo","PLACEBO_COMPARATOR","intraarticular saline injection (0,6-1ml)",[19],"Other: Placebo",[21,26],{"type":22,"name":9,"description":23,"armGroupLabels":24,"otherNames":25},"PROCEDURE","Intra-articular injection of platelet rich plasma (PRP)",[9],null,{"type":6,"name":15,"description":27,"armGroupLabels":28,"otherNames":25},"Intra-articular Saline injection (0,6-1ml)",[15],[30,35],{"name":31,"role":32,"phone":33,"phoneExt":25,"email":34},"Maria Wilcke, MD, PhD","CONTACT","+46708294613","maria.wilcke@regionstockholm.se",{"name":36,"role":32,"phone":25,"phoneExt":25,"email":37},"Johanna VonKieseritzky, MD. PhD","johanna.vonkieseritzky@regionstockholm.se",[39],{"facility":40,"status":41,"city":42,"state":25,"zip":43,"country":44,"countryCode":45,"cosmosGeoPoint":46,"geoPoint":51,"contacts":52},"Department of Hand Surgery Södersjukhuset","RECRUITING","Stockholm","S-11883","Sweden","SE",{"type":47,"coordinates":48},"Point",[49,50],18.06871,59.32938,{"lat":50,"lon":49},[53,55],{"name":54,"role":32,"phone":33,"phoneExt":25,"email":34},"Maria Wilcke, PhD",{"name":56,"role":32,"phone":25,"phoneExt":25,"email":37},"Johanna Von Kieseritzky, PhD",{"type":58,"investigatorFullName":59,"investigatorTitle":60,"investigatorAffiliation":5,"oldNameTitle":25,"oldOrganization":25},"PRINCIPAL_INVESTIGATOR","Maria Wilcke","Associate profesoor","100530954","a-study-on-the-effect-of-high-concentrated-platelet-rich-plasma-prp-on-osteoarthritis-in-the-thumb-base-100530954",false,"NCT06193499","A Study on the Effect of High-concentrated Platelet Rich Plasma (PRP) on Osteoarthritis in the Thumb Base.","Inclusion Criteria:\n\n* Osteoarthritis in the thumb base\n* Radiological Eaton Littler class 1-3.\n* Clinical signs of thumb base osteoarthritis )pain at palpation of the CMC-1 joint and pain during provocation\u002Fgrinding test).\n\nExclusion Criteria:\n\n* Rheumatoid arthritis\n* Ongoing infection in the hand or wrist\n* History of gout or pseudogout in the hand\n* Inability to co-operate with the follow-up protocol (language difficulties, severe psychiatric disorder, cognitive impairment, drug addiction).\n* Chronic pain syndrome \u002F centralized pain.\n* Intra-articular injection in the affected joint within 6 months.\n* Eaton Littler class 4 (symptomatic STT joint osteoarthritis).","ALL",{"count":69,"type":70},90,"ESTIMATED","INTERVENTIONAL",[73],"NA","This is a randomized double-blinded randomized comparison between injection of platelet rich plasma (PRP) and placebo for thumb basale osteoarthritis.",[76],"Osteoarthritis Thumb",[78,79,80,81],"CMC-1 joint","thumb basal joint","PRP","Platelet-rich plasma","2025-06-01",{"date":84,"type":85},"2025-06-03","ACTUAL",{"date":87,"type":85},"2024-01-17",{"date":89,"type":70},"2027-06-30",{"name":5,"class":6},1]