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Participants must be \\> 2 years old, and ≤ 14 years old (female) or ≤ 16 years old (males) at the time of signing the informed consent.\n2. A height assessment corresponding to a height Z-score of ≤ -2.25 SDs in reference to the general population of the same age and sex, as calculated using the Centers for Disease Control and Prevention (CDC) growth chart (https:\u002F\u002Fwww.cdc.gov\u002Fgrowthcharts\u002Fzscore.htm).\n3. Participants who have either never received hGH, or who are currently receiving hGH treatment.\n4. Historic stimulation test result with serum or plasma GH level greater than 10 μg\u002FL.\n5. Parent(s) or guardian(s) are willing and able to provide written, signed informed consent.\n\nExclusion Criteria:\n\n1. Diagnosis of systemic disease or condition that may cause short stature, eg renal, neoplastic, pulmonary, cardiac, gastrointestinal, immunologic and metabolic disease. Children with such diagnoses can be considered for inclusion if their condition is well controlled, at the discretion of the Medical Monitor.\n2. Known presence of one or more pituitary hormone deficiencies\n3. Bone age advanced over chronological age by more than 3 years.\n4. For hGH naïve participants, historic stimulation test result with serum or plasma GH level greater than 10 μg\u002FL or serum IGF-1 in the normal range for age (between -1.00 SDs and +2.00 SDs).\n5. For participants currently on hGH treatment, historic results before GH treatment of stimulation test with serum or plasma GH level greater than 10 μg\u002FL or serum IGF-1 test between -1.00 SDs and +2.00 SDs.\n6. 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