[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100624240":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":12,"centralContacts":16,"locations":10,"responsibleParty":22,"collaborators":10,"id":24,"slug":25,"hasResults":26,"nctId":27,"briefTitle":28,"officialTitle":29,"acronym":30,"eligibilityCriteria":31,"healthyVolunteers":26,"sex":32,"minAge":33,"maxAge":10,"enrollmentInfo":34,"targetDuration":10,"studyType":37,"phases":10,"briefSummary":38,"conditions":39,"keywords":41,"overallStatus":42,"whyStopped":10,"lastUpdateSubmitDate":43,"lastUpdatePostDateStruct":44,"startDateStruct":47,"completionDateStruct":49,"leadSponsor":51,"locationsCount":10},{"fullName":5,"class":6},"AbbVie","INDUSTRY",[8],{"label":9,"type":10,"description":11,"interventionNames":10},"Folate Receptor Alpha (FRα)",null,"Samples of eligible participants with ovarian cancer will be analyzed retrospectively for folate receptor alpha (FRα) expression.",[13],{"name":14,"affiliation":5,"role":15},"ABBVIE INC.","STUDY_DIRECTOR",[17],{"name":18,"role":19,"phone":20,"phoneExt":10,"email":21},"Caterina Golotta","CONTACT","+39 06 548891","caterina.golotta@abbvie.com",{"type":23,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR","100624240","a-study-to-evaluate-folate-receptor-alpha-fr-expression-in-adult-participants-with-ovarian-fallopian-tube-and-primary-peritoneal-cancer-in-italy-100624240",false,"NCT07407062","A Study to Evaluate Folate Receptor Alpha (FRα) Expression in Adult Participants With Ovarian, Fallopian Tube, and Primary Peritoneal Cancer in Italy","Folate Receptor Alpha Expression in Relapsed Ovarian, Fallopian Tube and Primary Peritoneal Cancer: a Realworld prEvalence Study in Italy","FORCE","Inclusion Criteria:\n\n* Relapsed ovarian, fallopian tube and primary peritoneal cancer\n* Histologically high-grade serous carcinoma\n* Presence of archived surgical tissue samples from participants with epithelial ovarian cancer at diagnosis and at 1st recurrence in the same participants\n* Available samples collected from January 1st, 2016 to study start date (defined as study site initiation visit date) that are considered adequate for the Ventana folate receptor alpha (FOLR1) RxDx assay by the site pathologist\n\nExclusion Criteria:\n\n* Histological ambiguous diagnosis upon review\n* Diagnosis based on cytology and without any biopsy or surgical specimen\n* Other histotypes than high grade serous ovarian cancer, fallopian tube cancer and primary peritoneal cancer\n* Archival or recurrent sample for the same participant not available","FEMALE","18 Years",{"count":35,"type":36},200,"ESTIMATED","OBSERVATIONAL","The purpose of this study is to evaluate the prevalence of folate receptor alpha (FRα)-positive status (≥75% viable tumor cells with moderate (2+) and\u002For strong (3+) membrane staining) in participants with high-grade serous ovarian, fallopian tube, and primary peritoneal cancer, stratified by time of sampling (initial diagnosis versus relapse), adhering to Ventana folate receptor alpha (FOLR1) RxDx (prescription diagnosis) assay Interpretation Guidance.",[40],"Cancer - Ovarian",[40],"NOT_YET_RECRUITING","2026-02-06",{"date":45,"type":46},"2026-02-12","ACTUAL",{"date":48,"type":36},"2026-02-28",{"date":50,"type":36},"2026-07",{"name":5,"class":6}]