[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100599146":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":25,"centralContacts":29,"locations":39,"responsibleParty":59,"collaborators":25,"id":63,"slug":64,"hasResults":65,"nctId":66,"briefTitle":67,"officialTitle":68,"acronym":25,"eligibilityCriteria":69,"healthyVolunteers":65,"sex":70,"minAge":71,"maxAge":72,"enrollmentInfo":73,"targetDuration":25,"studyType":76,"phases":77,"briefSummary":79,"conditions":80,"keywords":83,"overallStatus":42,"whyStopped":25,"lastUpdateSubmitDate":86,"lastUpdatePostDateStruct":87,"startDateStruct":90,"completionDateStruct":92,"leadSponsor":94,"locationsCount":95},{"fullName":5,"class":6},"Zhejiang University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Splenectomy group","EXPERIMENTAL","Open Debridement combined with Distal Pancreatectomy and Total Splenectomy",[13],"Procedure: Splenectomy",{"label":15,"type":10,"description":16,"interventionNames":17},"Control group","Open Debridement alone",[18],"Procedure: Control",[20,26],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"PROCEDURE","Splenectomy","Open Debridement combined with distal pancreatectomy and total splenectomy",[9],null,{"type":21,"name":27,"description":16,"armGroupLabels":28,"otherNames":25},"Control",[15],[30,35],{"name":31,"role":32,"phone":33,"phoneExt":25,"email":34},"Yun Zhang","CONTACT","086-18058715288","bigzyun1977@zju.edu.cn",{"name":36,"role":32,"phone":37,"phoneExt":25,"email":38},"Jian Zhang","086-18758197996","johnzhang@zju.edu.cn",[40],{"facility":41,"status":42,"city":43,"state":44,"zip":45,"country":46,"countryCode":47,"cosmosGeoPoint":48,"geoPoint":53,"contacts":54},"First Affiliated Hospital, Zhejiang University School of Medicine","RECRUITING","Hangzhou","Zhejiang","310003","China","CN",{"type":49,"coordinates":50},"Point",[51,52],120.16142,30.29365,{"lat":52,"lon":51},[55],{"name":56,"role":32,"phone":57,"phoneExt":25,"email":58},"Ting-Bo Liang","086-571-87236688","liangtingbo@zju.edu.cn",{"type":60,"investigatorFullName":61,"investigatorTitle":62,"investigatorAffiliation":5,"oldNameTitle":25,"oldOrganization":25},"PRINCIPAL_INVESTIGATOR","TingBo Liang","Director physician","100599146","a-study-to-evaluate-splenectomy-on-debridement-for-acute-necrotizing-pancreatitis-with-pancreatic-sinistral-portal-hypertension-100599146",false,"NCT07080697","A Study to Evaluate Splenectomy on Debridement for Acute Necrotizing Pancreatitis With Pancreatic Sinistral Portal Hypertension","The Impact of Splenectomy on Debridement Efficacy, Perioperative Recovery, and Prognosis in Patients With Acute Necrotizing Pancreatitis Complicated by Pancreatic Sinistral Portal Hypertension","Inclusion Criteria:\n\n1. Age between 18 and 75 years.\n2. Acute necrotic pancreatitis complicated by pancreatic sinistral portal hypertension.\n3. Patients undergoing open debridement for infected pancreatic necrosis\n\nExclusion Criteria:\n\n1. Patients with pre-existing heart, lung, liver, kidney, or other organ failure prior to acute pancreatitis (AP).\n2. Patients with pre-existing conditions such as cirrhosis that may lead to portal hypertension prior to AP.\n3. Patients with pre-existing hematological diseases prior to AP.\n4. Patients undergoing laparoscopic or nephroscopic debridement.","ALL","18 Years","75 Years",{"count":74,"type":75},66,"ESTIMATED","INTERVENTIONAL",[78],"NA","This study is a prospective, single-center, randomized controlled trial focusing on patients with acute necrotizing pancreatitis (ANP) complicated by pancreatic sinistral portal hypertension (PSPH). The study aims to study the impact of total splenectomy on the debridement efficacy, perioperative recovery, and prognosis of patients with ANP complicated by PSPH.",[81,82],"Acute Necrotizing Pancreatitis","Portal Hypertension",[81,84,85,22],"Pancreatic Sinistral Portal Hypertension","Debridement","2025-07-20",{"date":88,"type":89},"2025-07-23","ACTUAL",{"date":91,"type":75},"2025-07-30",{"date":93,"type":75},"2028-02-29",{"name":5,"class":6},1]