[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100612461":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":10,"centralContacts":35,"locations":44,"responsibleParty":62,"collaborators":64,"id":68,"slug":69,"hasResults":70,"nctId":71,"briefTitle":72,"officialTitle":73,"acronym":74,"eligibilityCriteria":75,"healthyVolunteers":70,"sex":76,"minAge":77,"maxAge":78,"enrollmentInfo":79,"targetDuration":10,"studyType":82,"phases":10,"briefSummary":83,"conditions":84,"keywords":87,"overallStatus":91,"whyStopped":10,"lastUpdateSubmitDate":92,"lastUpdatePostDateStruct":93,"startDateStruct":96,"completionDateStruct":98,"leadSponsor":100,"locationsCount":101},{"fullName":5,"class":6},"Liverpool Heart and Chest Hospital NHS Foundation Trust","OTHER",[8,16],{"label":9,"type":10,"description":11,"interventionNames":12},"Asthma",null,"Patients with suspected asthma",[13,14,15],"Diagnostic Test: Partial pressure of CO2 during tidal breathing","Diagnostic Test: FENO","Diagnostic Test: Spirometry",{"label":17,"type":10,"description":18,"interventionNames":19},"COPD","Patients with suspected COPD",[13,14,15],[21,26,31],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":10},"DIAGNOSTIC_TEST","Partial pressure of CO2 during tidal breathing","Partial pressure of CO2 during tidal breathing for diagnosis of asthma or COPD",[9,17],{"type":22,"name":27,"description":28,"armGroupLabels":29,"otherNames":30},"FENO","Fractional exhaled nitric oxide",[9,17],[28],{"type":22,"name":32,"description":33,"armGroupLabels":34,"otherNames":10},"Spirometry","Spirometry with or without bronchodilation (if indicated)",[9,17],[36,41],{"name":37,"role":38,"phone":39,"phoneExt":10,"email":40},"Hassan Burhan, MBChB FRCP","CONTACT","0151 254 3036","Hassan.Burhan@liverpoolft.nhs.uk",{"name":42,"role":38,"phone":43,"phoneExt":10,"email":10},"Thomas FitzMaurice, MBChB BSc PGCME MRCP(UK) PhD","0151 254 3055",[45],{"facility":5,"status":10,"city":46,"state":47,"zip":48,"country":49,"countryCode":50,"cosmosGeoPoint":51,"geoPoint":56,"contacts":57},"Liverpool","Merseyside","L14 3PE","United Kingdom","UK",{"type":52,"coordinates":53},"Point",[54,55],-2.97794,53.41058,{"lat":55,"lon":54},[58],{"name":59,"role":38,"phone":60,"phoneExt":10,"email":61},"Freddy Frost, BMedSci BMBS MRCP MD","0151 600 1616","freddy.frost@lhch.nhs.uk",{"type":63,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR",[65],{"name":66,"class":67},"TidalSense","INDUSTRY","100612461","a-study-to-understand-the-accuracy-of-a-new-breathing-device-compared-to-standard-testing-for-asthma-and-copd-100612461",false,"NCT07253883","A Study to Understand the Accuracy of a New Breathing Device Compared to Standard Testing for Asthma and COPD","A Diagnostic Accuracy Study: N-Tidal Assessment for Respiratory Diagnosis Compared to Using Standard Testing","STARDUST","Inclusion Criteria:\n\n* Age ≥ 18 years\n* Referred for respiratory diagnostic testing with a clinical suspicion of asthma or COPD\n* Participant is willing and able to provide informed consent\n\nExclusion Criteria:\n\n* Referred for respiratory diagnostic testing for a condition other than asthma or COPD, with no mention in the referral of a clinical suspicion of COPD or asthma\n* Participants who, in the opinion of the chief investigator, or their delegate, are unlikely to comply with the requirements of the study\n* Inability to give written informed consent\n* Participants who are acutely unwell\n* Patients unable to breathe through their mouths e.g. tracheostomy patients","ALL","18 Years","110 Years",{"count":80,"type":81},1200,"ESTIMATED","OBSERVATIONAL","The diagnosis of either asthma or chronic obstructive pulmonary disease (COPD) is currently based on a combination of symptoms, different lung tests and sometimes a 'trial by treatment'. Both COPD and Asthma tests currently include forced breathing using a test known as spirometry which can be difficult and uncomfortable for people to perform and needs expert interpretation. Asthma can require multiple tests in sequence which can make the process of diagnosis long and inconvenient for patients. In the UK, there have been challenges providing enough testing for COPD and asthma, in part because the tests are challenging to provide in the community to everyone who needs one.\n\nThe STARDUST study aims to test and develop new ways of diagnosing asthma and COPD that are quick, accurate and easy for patient and healthcare professionals to perform. People who have been referred for routine lung testing will breathe normally in and out into a handheld device called the N-Tidal Handset for 75 seconds. This device measures how the level of carbon dioxide (CO2) changes in the breath as people breath through it. The information gathered on the N-Tidal Handsets, called breath records or capnograms, will not be used to alter the diagnosis of any participants in the study.\n\nAfter the capnograms have been collected, the research team will test 'algorithms' that have been developed using artificial intelligence, to see if they can accurately identify the correct diagnosis. Information collected in the study will also be used to make improvements in these algorithms.\n\nIf confirmed to be accurate, these algorithms could be used in clinical practice to help healthcare professionals make faster, more accessible and accurate diagnoses, especially in settings like GP clinics in the community where access to specialist tests may be limited.",[85,86],"Asthma (Diagnosis)","COPD (Chronic Obstructive Pulmonary Disease)",[9,17,88,89,90],"End tidal CO2","Diagnostics","Machine learning","NOT_YET_RECRUITING","2026-04-21",{"date":94,"type":95},"2026-04-24","ACTUAL",{"date":97,"type":81},"2026-04-01",{"date":99,"type":81},"2027-05-19",{"name":5,"class":6},1]