[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100574742":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":28,"centralContacts":29,"locations":41,"responsibleParty":73,"collaborators":75,"id":79,"slug":80,"hasResults":81,"nctId":82,"briefTitle":83,"officialTitle":84,"acronym":85,"eligibilityCriteria":86,"healthyVolunteers":81,"sex":87,"minAge":88,"maxAge":89,"enrollmentInfo":90,"targetDuration":28,"studyType":93,"phases":94,"briefSummary":96,"conditions":97,"keywords":100,"overallStatus":105,"whyStopped":28,"lastUpdateSubmitDate":106,"lastUpdatePostDateStruct":107,"startDateStruct":110,"completionDateStruct":112,"leadSponsor":114,"locationsCount":115},{"fullName":5,"class":6},"First Affiliated Hospital Xi'an Jiaotong University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"ABA Therapy with active TEAS","ACTIVE_COMPARATOR","The TEAS intervention is delivered using an electroacupuncture device (SDZ-V, Hwato, Soochow Medical Instruments Co., Ltd., China). Self-adhesive electrodes are placed at acupoints Zhongwan (RN12), bilateral Tianshu (ST25), Qihai (RN6), and Guanyuan (RN4). Stimulation is applied using dense-sparse wave alternating frequencies (3 Hz for 2 s cycles) at an intensity of 3-10 mA, adjusted to the participant's tolerance. Each session lasts 30 minutes, conducts once daily, five days per week, for a total of 40 sessions.\n\nThe ABA therapy focuses on enhancing skills in areas such as social interaction, communication, academics, motor function, and self-care. Each session lasts 30 minutes, conducts once daily, five days per week, for a total of 40 sessions.",[13],"Device: abdominal transcutaneous electrical acupoint stimulation (abdominal TEAS)",{"label":15,"type":16,"description":17,"interventionNames":18},"ABA Therapy with Sham TEAS","SHAM_COMPARATOR","The sham TEAS intervention is delivered using an electroacupuncture device (SDZ-V, Hwato, Soochow Medical Instruments Co., Ltd., China). Self-adhesive electrodes are placed at acupoints Zhongwan (RN12), bilateral Tianshu (ST25), Qihai (RN6), and Guanyuan (RN4). Stimulation is applied using dense-sparse wave alternating frequencies (3 Hz for 2 s cycles) at an intensity of 0 mA. Each session lasts 30 minutes, conducts once daily, five days per week, for a total of 40 sessions.\n\nABA therapy focuses on enhancing skills in areas such as social interaction, communication, academics, motor function, and self-care. Each session lasts 30 minutes, conducts once daily, five days per week, for a total of 40 sessions.",[13],[20],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"DEVICE","abdominal transcutaneous electrical acupoint stimulation (abdominal TEAS)","The TEAS intervention is delivered using an electroacupuncture device (SDZ-V, Hwato, Soochow Medical Instruments Co., Ltd., China). Self-adhesive electrodes are placed at acupoints Zhongwan (RN12), bilateral Tianshu (ST25), Qihai (RN6), and Guanyuan (RN4). Stimulation is applied using dense-sparse wave alternating frequencies (3 Hz for 2 s cycles) at an intensity of 3-10 mA, adjusted to the participant's tolerance. Each session lasts 30 minutes, conducts once daily, five days per week, for a total of 40 sessions.\n\nThe ABA therapy focuses on enhancing skills in areas such as social interaction, communication, academics, motor function, and self-care. ABA is delivered in a variety of settings, including school, home, clinic, and other community settings. The goal of treatment is to help children function as independently and successfully as possible. Each session lasts 30 minutes, conducts once daily, five days per week, for a total of 40 sessions.",[15,9],[26,27],"TEAS","Applied Behavior Analysis (ABA) therapy",null,[30,36],{"name":31,"role":32,"phone":33,"phoneExt":34,"email":35},"Lixia Zhuo, PhD","CONTACT","China: +86 029-85324424","+86 1829286650","1829286650@163.com",{"name":37,"role":32,"phone":38,"phoneExt":39,"email":40},"Yan Li, PhD","China: +86 029-85323539","+86 1372041861","liyanxjtu@xjtu.edu.cn",[42,61],{"facility":43,"status":28,"city":44,"state":45,"zip":46,"country":47,"countryCode":48,"cosmosGeoPoint":49,"geoPoint":54,"contacts":55},"The first affiliated hospital of Xi'an Jiaotong University","Xi'an","Shaanxi","710061","China","CN",{"type":50,"coordinates":51},"Point",[52,53],108.92861,34.25833,{"lat":53,"lon":52},[56,59],{"name":31,"role":32,"phone":33,"phoneExt":57,"email":58},"+8618292866500","18292866500@163.com",{"name":37,"role":60,"phone":28,"phoneExt":28,"email":28},"PRINCIPAL_INVESTIGATOR",{"facility":62,"status":28,"city":44,"state":45,"zip":63,"country":47,"countryCode":48,"cosmosGeoPoint":64,"geoPoint":66,"contacts":67},"Xi'an Children's Hospital","710069",{"type":50,"coordinates":65},[52,53],{"lat":53,"lon":52},[68,72],{"name":69,"role":32,"phone":70,"phoneExt":28,"email":71},"Jie Zhang, MD","China: +86 029-87692536","zhangjiexach@xjtu.edu.cn",{"name":69,"role":60,"phone":28,"phoneExt":28,"email":28},{"type":74,"investigatorFullName":28,"investigatorTitle":28,"investigatorAffiliation":28,"oldNameTitle":28,"oldOrganization":28},"SPONSOR",[76],{"name":77,"class":78},"Xian Children's Hospital","OTHER_GOV","100574742","abdominal-transcutaneous-electrical-acupoint-stimulation-on-children-with-autism-spectrum-disorder-100574742",false,"NCT06763237","Abdominal Transcutaneous Electrical Acupoint Stimulation on Children With Autism Spectrum Disorder","Abdominal Transcutaneous Electrical Acupoint Stimulation on Children With Autism Spectrum Disorder: A Randomized Clinical Trial","TEAS\u002FASD","Inclusion Criteria:\n\n* Being diagnosed as autism based on the DSM-V and Autism Diagnostic Observation Schedule, Second Edition (ADOS-2)\n* Aged 3 to 6 years\n\nExclusion Criteria:\n\n* Diagnosed with other organic diseases (such as severe hearing and visual impairment, brain trauma) and neurological disease (e.g., epilepsy, Rett syndrome), or psychiatric disorder (schizophrenia, bipolar affective disorder, etc)\n* Oral or injected antibiotics within 30 days before screening\n* History of acupuncture, electroacupuncture, TEAS treatment before screening\n* Taking antipsychotic drugs and psychobiotic supplements within 30 days before screening","ALL","3 Years","6 Years",{"count":91,"type":92},42,"ESTIMATED","INTERVENTIONAL",[95],"NA","The goal of this clinical trial is to learn if abdominal transcutaneous electrical acupoint stimulation (abdominal TEAS) works to treat autism spectrum disorder (ASD) in children. It will also learn about the safety of abdominal TEAS. The main questions it aims to answer are:\n\nDoes abdominal TEAS a safe and effective treatment for children with autism spectrum disorder and gastrointestinal symptoms? Researchers will compare abdominal TEAS to a placebo (a sham abdominal TEAS without stimulation) to see if abdominal TEAS works to treat ASD.\n\nParticipants will:\n\nTake abdominal TEAS or sham abdominal TEAS 5 days a week for 8 weeks. Visit the clinic once every 4 weeks for checkups and tests Keep a diary of their symptoms.",[98,99],"Autism Spectrum Disorder","Autism in Children",[101,102,103,104],"Transcutaneous electrical acupoint stimulation","Gastrointestinal symptoms","Children","Autism spectrum disorder","NOT_YET_RECRUITING","2025-01-02",{"date":108,"type":109},"2025-01-08","ACTUAL",{"date":111,"type":92},"2025-01-10",{"date":113,"type":92},"2026-01-10",{"name":5,"class":6},2]