[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100561190":3},{"organization":4,"armGroups":7,"interventions":7,"overallOfficials":8,"centralContacts":13,"locations":7,"responsibleParty":23,"collaborators":7,"id":27,"slug":28,"hasResults":29,"nctId":30,"briefTitle":31,"officialTitle":32,"acronym":7,"eligibilityCriteria":33,"healthyVolunteers":29,"sex":34,"minAge":35,"maxAge":36,"enrollmentInfo":37,"targetDuration":7,"studyType":40,"phases":7,"briefSummary":41,"conditions":42,"keywords":7,"overallStatus":44,"whyStopped":7,"lastUpdateSubmitDate":45,"lastUpdatePostDateStruct":46,"startDateStruct":49,"completionDateStruct":51,"leadSponsor":53,"locationsCount":7},{"fullName":5,"class":6},"Minia University","OTHER",null,[9],{"name":10,"affiliation":11,"role":12},"Jozef Zekry, Professor","Minia U","STUDY_CHAIR",[14,19],{"name":15,"role":16,"phone":17,"phoneExt":7,"email":18},"Andrew Emad thabet","CONTACT","01226360150","loloandrewemad@gmail.com",{"name":20,"role":16,"phone":21,"phoneExt":7,"email":22},"Mohamed Mostafa ali","01555429805","andrewemad878@yahoo.com",{"type":24,"investigatorFullName":25,"investigatorTitle":26,"investigatorAffiliation":5,"oldNameTitle":7,"oldOrganization":7},"PRINCIPAL_INVESTIGATOR","Andrew Emad Thabet Ebrahim","Accuracy of venous excess ultrasound (VEXUS) score versus central venous pressure to assess volume status in patients with severe sepsis","100561190","accuracy-of-venous-excess-ultrasound-vexus-score-versus-central-venous-pressure-in-patients-with-severe-sepsis-100561190",false,"NCT06586931","Accuracy of Venous Excess Ultrasound (VEXUS) Score Versus Central Venous Pressure in Patients With Severe Sepsis","Accuracy of Venous Excess Ultrasound (VEXUS) Score Versus Central Venous Pressure to Assess Volume Status in Patients With Severe Sepsis","Inclusion Criteria:\n\n* adult patients (≥ 18 years old) with the diagnosis of severe sepsis and clinical indication to be admitted in critical care units are recruited. Sepsis should be suspected to be the primary cause of their acute illness by the treating physician, consistent with the\n\nSurviving Sepsis Campaign Guidelines (2021) :\n\n* Life-threatening organ dysfunction\n* Diagnosis of infection Some patients diagnosed with sepsis will not meet the criteria, but will be eligible for the study if the treating physician makes a clinical diagnosis of severe sepsis.\n\nExclusion Criteria:\n\n* 1\\. Refusal to participate 2. Patients in hemodialysis program 3. Patients with previously known conditions that interfere with portal Doppler assessments, namely liver cirrhosis, or severe tricuspid regurgitation with structural heart disease. If any of these conditions are identified during the present episode, the patient would also be excluded.\n\n  4\\. Age \\\u003C 18 years 5. Patients subjected to withdrawal of care 6. Hemodynamic instability due to active hemorrhage 7. Acute coronary syndrome 8. Indication for immediate surgery 9. Received CPR within 24 hours of enrollment 10. Pregnancy","ALL","18 Years","75 Years",{"count":38,"type":39},60,"ESTIMATED","OBSERVATIONAL","assessing septic patients with a noninvasive ultrasound protocol, and earlier identification of fluid overload to help clinicians decide whether to administer supplemental fluid therapy or suspend its administration and to evaluate the possible relation between the different VExUS grades and the adverse effects of intensive fluid administration",[43],"Sepsis, Severe","NOT_YET_RECRUITING","2024-09-04",{"date":47,"type":48},"2024-09-19","ACTUAL",{"date":50,"type":39},"2024-10-01",{"date":52,"type":39},"2025-11",{"name":5,"class":6}]