[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100583085":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":10,"centralContacts":28,"locations":38,"responsibleParty":55,"collaborators":10,"id":59,"slug":60,"hasResults":61,"nctId":62,"briefTitle":63,"officialTitle":64,"acronym":10,"eligibilityCriteria":65,"healthyVolunteers":61,"sex":66,"minAge":67,"maxAge":68,"enrollmentInfo":69,"targetDuration":10,"studyType":72,"phases":10,"briefSummary":73,"conditions":74,"keywords":76,"overallStatus":41,"whyStopped":10,"lastUpdateSubmitDate":80,"lastUpdatePostDateStruct":81,"startDateStruct":84,"completionDateStruct":86,"leadSponsor":88,"locationsCount":89},{"fullName":5,"class":6},"Ohio State University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"With acellular matrix",null,"Participants who are having the GBR procedure done with the use of the acellular matrix material to cover the graft\u002Fwound",[13],"Procedure: Acellular matrix",{"label":15,"type":10,"description":16,"interventionNames":17},"Surgical closure","Participants who are having the GBR procedure done by having the wound closed without the acellular material",[18],"Procedure: Surgical closure",[20,25],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":10},"PROCEDURE","Acellular matrix","Wound closure is obtained by use of acellular matrix material placed over the exposed barrier membrane. The procedure itself is not part of the research study, nor is the decision to use this procedure, but it is the condition of interest to the research.",[9],{"type":21,"name":15,"description":26,"armGroupLabels":27,"otherNames":10},"Wound from the graft is surgically closed, with no use of the acellular matrix. The procedure itself is not part of the research study, nor is the decision to use this procedure, but it is the condition of interest to the research.",[15],[29,34],{"name":30,"role":31,"phone":32,"phoneExt":10,"email":33},"Binnaz Leblebicioglu, DDS, MS, PhD","CONTACT","614-292-0371","leblebicioglu.1@osu.edu",{"name":35,"role":31,"phone":36,"phoneExt":10,"email":37},"Francesca Racca, DMD","(614) 292-0371","racca.2@osu.edu",[39],{"facility":40,"status":41,"city":42,"state":43,"zip":44,"country":45,"countryCode":46,"cosmosGeoPoint":47,"geoPoint":52,"contacts":53},"The Ohio State University Graduate Periodontics Clinic","RECRUITING","Columbus","Ohio","43210","United States","US",{"type":48,"coordinates":49},"Point",[50,51],-82.99879,39.96118,{"lat":51,"lon":50},[54],{"name":30,"role":31,"phone":32,"phoneExt":10,"email":33},{"type":56,"investigatorFullName":57,"investigatorTitle":58,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"PRINCIPAL_INVESTIGATOR","Binnaz Leblebicioglu","Professor","100583085","acellular-collagen-matrix-as-a-tool-to-obtain-wound-closure-following-a-guided-bone-regeneration-procedure-100583085",false,"NCT06871735","Acellular Collagen Matrix as a Tool to Obtain Wound Closure Following a Guided Bone Regeneration Procedure","Acellular Collagen Matrix (Mucograft) as a Tool to Obtain Wound Closure Following GBR Procedures","Inclusion Criteria:\n\n* Have a missing tooth or teeth which are planned to be replaced with an implant\n* Need for guided bone regeneration procedure to increase the bone available for implant placement\n* Systemically healthy with no contraindications for bone grafting and\u002For implant surgery\n* No chronic sinus problems\n* Non-smoker\n* No need for removable temporary restorations during wound healing.\n\nExclusion Criteria:\n\n* Patients that have sufficient bone volume to perform implant placement through conventional drilling protocol without any pre-implant GBR procedure\n* Indications for pre-implant\u002Fpre-GBR soft tissue grafting procedure to increase existing soft tissue contours\n* The need to wear a removable temporary restoration during healing","ALL","21 Years","75 Years",{"count":70,"type":71},30,"ESTIMATED","OBSERVATIONAL","Guided bone regeneration (GBR) is a procedure used to increase the amount of bone volume in the jaw before placing a dental implant. It is needed when a lot of bone has been lost around the spot where a tooth has been lost or extracted.\n\nAn incision is made, bone grafting material is placed in that spot, there is a membrane put over it as a barrier, then gum tissue has to be pulled back over it. Usually, this is enough to cover the whole wound, but sometimes the barrier membrane can't be covered with tissue the whole way without too much pulling, and the barrier membrane is still exposed.\n\nIn that case, one thing that can be done is to place another material, an acellular collagen matrix, over the barrier membrane and secure it there. This material has been shown to help with the healing in these cases.\n\nParticipants in this study will be clinic patients who have been determined to need a GBR procedure. Participants will get the GBR. If the barrier membrane is still exposed, then the acellular matrix material will be placed. This study will compare the healing outcomes and the success of the GBR depending on whether the acellular matrix material was used. The procedure itself is not part of the study. The only people in the study are patients who are already planning to have this procedure done as part of their dental care.\n\nIt is important to note that the research study will not affect the care that the patient is given, or whether or not the acellular matrix material is used. That will be decided by the dental surgeon who is treating them, based on their clinical judgement. The research study will only observe and compare the outcomes.\n\nFor the study, participants will have some additional clinical measurements made, besides the ones that are done as part of the follow-up care, and will be asked questions about their experience.",[75],"Bone Graft",[77,78,79],"GBR","Bone graft","dental implant","2026-02-11",{"date":82,"type":83},"2026-02-13","ACTUAL",{"date":85,"type":83},"2023-04-13",{"date":87,"type":71},"2026-10",{"name":5,"class":6},1]