[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100562278":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":29,"centralContacts":34,"locations":12,"responsibleParty":40,"collaborators":43,"id":46,"slug":47,"hasResults":48,"nctId":49,"briefTitle":50,"officialTitle":51,"acronym":52,"eligibilityCriteria":53,"healthyVolunteers":48,"sex":54,"minAge":55,"maxAge":56,"enrollmentInfo":57,"targetDuration":12,"studyType":60,"phases":61,"briefSummary":63,"conditions":64,"keywords":69,"overallStatus":72,"whyStopped":12,"lastUpdateSubmitDate":73,"lastUpdatePostDateStruct":74,"startDateStruct":77,"completionDateStruct":79,"leadSponsor":81,"locationsCount":12},{"fullName":5,"class":6},"Karolinska University Hospital","OTHER",[8,13],{"label":9,"type":10,"description":11,"interventionNames":12},"Control group with standard lower-limb immobilization","NO_INTERVENTION","The control group will be treated according to the standard regimen with a lower limb immobilization in a stable orthosis during eight weeks.",null,{"label":14,"type":15,"description":16,"interventionNames":17},"Intervention group with additional Neuromuscular Electrical Stimulation'","EXPERIMENTAL","The intervention group will during the eight weeks lower limb immobilization receive an additional intervention with calf Neuromuscular Electrical Stimulation (C-NMES) underneath the orthosis.",[18],"Device: Neuromuscular Electrical Stimulation",[20],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"DEVICE","Neuromuscular Electrical Stimulation","Patients will be instructed to apply the wearable NMES-therapy continuously, both day and night at least 10h\u002Fdaily.",[14],[26,27,28],"Electrical Stimulation","NMES","C-NMES",[30],{"name":31,"affiliation":32,"role":33},"Paul Ackermann, Prof,MD,PhD","Karolinska Institutet and Karolinska University Hospital","PRINCIPAL_INVESTIGATOR",[35],{"name":36,"role":37,"phone":38,"phoneExt":12,"email":39},"Luigi Belcatro, Res.Nurse","CONTACT","0046-735060907","luigi.belcastro@regionstockholm.se",{"type":33,"investigatorFullName":41,"investigatorTitle":42,"investigatorAffiliation":5,"oldNameTitle":12,"oldOrganization":12},"Paul Ackermann","Professor",[44],{"name":45,"class":6},"Danderyd Hospital","100562278","achilles-tendon-rupture---intervention-with-electrical-stimulation-100562278",false,"NCT06601088","Achilles Tendon Rupture - Intervention With Electrical Stimulation","Acute Achilles Tendon Rupture - Intervention With Neuromuscular Electrical Stimulation","C-NMES-ATR","Inclusion Criteria:\n\n* Diagnosed with acute unilateral Achilles tendon rupture\n* Included within 10 days after injury.\n\nExclusion Criteria:\n\n* Inability to give consent to participate,\n* ongoing treatment with anticoagulants,\n* known allergy to contrast agents,\n* planned follow-up at another hospital,\n* inability to follow instructions,\n* known renal failure,\n* heart failure with pitting edema,\n* thrombophlebitis,\n* thromboembolic disease within the last 3 months,\n* previous surgery of the tendon,\n* known malignancy,\n* hemophilia,\n* pregnancy,\n* treatment with high doses of acetylsalicylic acid.","ALL","18 Years","75 Years",{"count":58,"type":59},220,"ESTIMATED","INTERVENTIONAL",[62],"NA","Acute Achilles tendon rupture (ATR) is an injury that is commonly associated with complications, such as blood clotting, muscle loss and tendon lengthening, all of which affect the long-term outcome and return to sports. These complication are related to the treatment of ATR with lower leg immobilization in a boot.\n\nThe investigators aim to demonstrate that an intervention with calf neuromuscular electrical stimulation (C-NMES) during leg immobilization after ATR can 1) reduce blood clots, 2) lower the degree of muscle loss, 3) decrease tendon lengthening and 4) improve long-term outcome.",[65,66,67,68],"Achilles Tendon Ruptures","Immobilization","Venous Thromboembolism (VTE)","Muscle Atrophy",[70,71],"neuromuscular electrical stimulation","duplex ultrasound","NOT_YET_RECRUITING","2024-09-15",{"date":75,"type":76},"2024-09-19","ACTUAL",{"date":78,"type":59},"2025-01-15",{"date":80,"type":59},"2026-12-30",{"name":5,"class":6}]