[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100626493":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":25,"centralContacts":29,"locations":35,"responsibleParty":52,"collaborators":54,"id":58,"slug":59,"hasResults":60,"nctId":61,"briefTitle":62,"officialTitle":62,"acronym":25,"eligibilityCriteria":63,"healthyVolunteers":60,"sex":64,"minAge":65,"maxAge":25,"enrollmentInfo":66,"targetDuration":25,"studyType":69,"phases":70,"briefSummary":72,"conditions":73,"keywords":77,"overallStatus":38,"whyStopped":25,"lastUpdateSubmitDate":82,"lastUpdatePostDateStruct":83,"startDateStruct":86,"completionDateStruct":88,"leadSponsor":90,"locationsCount":91},{"fullName":5,"class":6},"Thomas Jefferson University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Immediate Treatment","EXPERIMENTAL","These participants will receive access to the toolkit immediately and use it as instructed for the next six weeks.",[13],"Behavioral: ACT with CF Self-Help Toolkit",{"label":15,"type":6,"description":16,"interventionNames":17},"Waitlist","These participants will wait six weeks and be compared to the immediate treatment arm at six weeks before then receiving the treatment over the next six weeks.",[13,18],"Other: Waitlist",[20,26],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"BEHAVIORAL","ACT with CF Self-Help Toolkit","The ACT with CF Self-Help Toolkit will include 6 main modules, each with 3 or 4 kernels, which will be short videos, in which participants will learn new ways to manage uncomfortable experiences and feelings (e.g., anxiety, depression) and to engage in positive behaviors. These videos are based on the main interventions in our ACT with CF individual therapy protocol. For example, the first main module focuses on how the participant wants to live their life (Values Clarification Intervention), and the kernels in this module are 1-3 minute video clips demonstrating different ways to figure this out (Card Sort, 70th Birthday exercise, accessing barriers). This intervention is directly adapted from the ACT with CF manual, which has been studied previously in several forms and studies.",[9,15],null,{"type":6,"name":15,"description":27,"armGroupLabels":28,"otherNames":25},"Participants in the waitlist condition will wait for six weeks before receiving the ACT with CF Self-Help Toolkit",[15],[30],{"name":31,"role":32,"phone":33,"phoneExt":25,"email":34},"Virginia O'Hayer, PhD","CONTACT","919-943-6738","virginia.ohayer@jefferson.edu",[36],{"facility":37,"status":38,"city":39,"state":40,"zip":41,"country":42,"countryCode":43,"cosmosGeoPoint":44,"geoPoint":49,"contacts":50},"Thomas Jefferson University Hospital","RECRUITING","Philadelphia","Pennsylvania","19107","United States","US",{"type":45,"coordinates":46},"Point",[47,48],-75.16362,39.95238,{"lat":48,"lon":47},[51],{"name":31,"role":32,"phone":33,"phoneExt":25,"email":34},{"type":53,"investigatorFullName":25,"investigatorTitle":25,"investigatorAffiliation":25,"oldNameTitle":25,"oldOrganization":25},"SPONSOR",[55],{"name":56,"class":57},"Boomer Esiason Foundation","UNKNOWN","100626493","act-with-cf-self-help-toolkit-100626493",false,"NCT07436351","ACT With CF Self-Help Toolkit","Inclusion Criteria:\n\n* 18 years or older\n* Existing diagnosis of cystic fibrosis\n* PHQ-9 score \\>4 or GAD-7 score \\>4\n\nExclusion Criteria:\n\n* History of suicide attempts or acute suicidal ideation on clinical assessment\n* Presence of psychotic disorder or symptoms\n* Presence of psychiatric disorders that interfere with participation in the study, judged by the study or treating clinician\n* Presence of other medical conditions that interfere with participation in the study, judged by the study or treating clinician","ALL","18 Years",{"count":67,"type":68},60,"ESTIMATED","INTERVENTIONAL",[71],"NA","Acceptance and Commitment Therapy (ACT) tailored to meet the needs of adults living with cystic fibrosis (ACT with CF) is a newer form of talk therapy that has been shown to reduce anxiety \\& depression and improve psychological flexibility, and value-based living. The investigators are now trying to find out whether a self-help version of this treatment (ACT with CF - Self Help Toolkit) is also effective in reducing anxiety and depression and improving psychological flexibility and value-based living in adults with CF.\n\nAdults with cystic fibrosis are at increased risk for anxiety and depression. This study examines whether a patient-facing therapy, ACT with CF - Self Help Toolkit can help to reduce anxiety and depression among adults with CF. This treatment can be accessed on the participant's smartphone.",[74,75,76],"Cystic Fibrosis (CF)","Depressive and Anxiety Disorders","Psychological Flexibility",[78,79,80,81],"cystic fibrosis","ACT","CF","chronic illness","2026-02-27",{"date":84,"type":85},"2026-03-03","ACTUAL",{"date":87,"type":85},"2026-01-20",{"date":89,"type":68},"2027-04",{"name":5,"class":6},1]