[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100546369":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":10,"centralContacts":10,"locations":19,"responsibleParty":38,"collaborators":10,"id":42,"slug":43,"hasResults":44,"nctId":45,"briefTitle":46,"officialTitle":47,"acronym":10,"eligibilityCriteria":48,"healthyVolunteers":44,"sex":49,"minAge":50,"maxAge":51,"enrollmentInfo":52,"targetDuration":55,"studyType":56,"phases":10,"briefSummary":57,"conditions":58,"keywords":10,"overallStatus":61,"whyStopped":10,"lastUpdateSubmitDate":62,"lastUpdatePostDateStruct":63,"startDateStruct":66,"completionDateStruct":68,"leadSponsor":70,"locationsCount":71},{"fullName":5,"class":6},"Fudan University","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Observation",null,"Active surveillance",[13],"Procedure: Active surveillance",[15],{"type":16,"name":11,"description":17,"armGroupLabels":18,"otherNames":10},"PROCEDURE","Conduct thoracic computed tomography scans every 12 months. If progression occurs, the treamtent approach would involve surgery.",[9],[20],{"facility":21,"status":10,"city":22,"state":10,"zip":10,"country":23,"countryCode":24,"cosmosGeoPoint":25,"geoPoint":30,"contacts":31},"Fudan University Shanghai Cancer Center","Shanghai","China","CN",{"type":26,"coordinates":27},"Point",[28,29],121.45806,31.22222,{"lat":29,"lon":28},[32],{"name":33,"role":34,"phone":35,"phoneExt":36,"email":37},"Haoxuan Wu","CONTACT","86-64175590","63189","haoxuanwu@hotmail.com",{"type":39,"investigatorFullName":40,"investigatorTitle":41,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"PRINCIPAL_INVESTIGATOR","Haiquan Chen","Director in the Department of Thoracic Surgery, FUSCC","100546369","active-surveillance-for-limited-ggns-100546369",false,"NCT06394037","Active Surveillance for Limited GGNs","Active Surveillance for Patients with Limited Ground-glass Nodules in China: a Prospective Multi-center Single-arm Trial (ECTOP-1028)","Patients eligible for enrollment in the study are required to meet all the following criteria.\n\n1. Demonstrates the following on thin-section computed tomography (TSCT) scan:\n\n   1. Presence of one or two GGNs (bilateral lesions are permitted).\n   2. All lesions have remained stable without regression or enlargement for at least 3 months.\n   3. The dominant lesion (the lesion with the largest maximum tumor diameter) has a maximum tumor diameter ≥0.6cm and ≤2cm.\n   4. CTR ≤0.25 in lesions.\n   5. No lymph node with a diameter \\>1cm in the mediastinal view.\n   6. Not adjacent to the pleura in dominant lesion and no sign of pleural retraction in any lesions.\n2. Has not previously undergo any anti-tumor drug or radiation therapy for the lung lesions.\n3. Aged 18-75 years.\n4. Eastern Cooperative Oncology Group (ECOG) performance status of 0 or 1.\n5. Written informed consent.\n\nPatients will be excluded if they meet any of the following criteria.\n\n1. History of any prior malignancies within the past 5 years.\n2. History of lung surgery.\n3. History of interstitial pneumonia, pulmonary fibrosis or other severe pulmonary diseases.\n4. Presence of severe or uncontrolled diseases that may possibly reduce the 10-year life expectancy.","ALL","18 Years","75 Years",{"count":53,"type":54},387,"ESTIMATED","10 Years","OBSERVATIONAL","This study is a single-arm, multi-center, phase III trial conducted under the Eastern Cooperative Thoracic Oncoloy Project (ECTOP) . The primary objective of the study is to assess the 5-year overall survival of patients with one or two ground-glass opacities by employing an active surveillance approach rather than immediate surgical resection.",[59,60],"Lung Ground-glass Opacities","Active Surveillance","NOT_YET_RECRUITING","2025-01-29",{"date":64,"type":65},"2025-01-31","ACTUAL",{"date":67,"type":54},"2025-05-01",{"date":69,"type":54},"2038-05-01",{"name":5,"class":6},1]