[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100607119":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":30,"centralContacts":34,"locations":42,"responsibleParty":64,"collaborators":66,"id":70,"slug":71,"hasResults":72,"nctId":73,"briefTitle":74,"officialTitle":75,"acronym":76,"eligibilityCriteria":77,"healthyVolunteers":72,"sex":78,"minAge":79,"maxAge":80,"enrollmentInfo":81,"targetDuration":25,"studyType":84,"phases":85,"briefSummary":87,"conditions":88,"keywords":90,"overallStatus":45,"whyStopped":25,"lastUpdateSubmitDate":94,"lastUpdatePostDateStruct":95,"startDateStruct":98,"completionDateStruct":100,"leadSponsor":102,"locationsCount":103},{"fullName":5,"class":6},"Baylor University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Activities-based locomotor training (AB-LT)","EXPERIMENTAL","Child will participate in a 3-week intensive AB-LT training program. The child will attend the AB-LT session for a total of 3 hours, 5 days a week for 3 weeks. The AB-LT session will consist of 1 hour of walking and standing in a harness on a treadmill, followed by an hour of play-based physical therapy, then followed by a final 1 hour of walking and standing in a harness on a treadmill. All sessions will be run by a licensed physical therapist who is trained in AB-LT.",[13],"Other: Activities-based locomotor training",{"label":15,"type":16,"description":17,"interventionNames":18},"Usual care","ACTIVE_COMPARATOR","During this arm, the child will resume or continue their usual therapy schedule, which may include physical therapy, occupational therapy, and\u002For speech language pathology. No restrictions will be placed on the type or amount of therapy in which the child can participate.",[19],"Other: physical therapy",[21,26],{"type":6,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"Activities-based locomotor training","Activities-based locomotor training involves placing the child in a partial body-weight supported (PBWS) system over a treadmill. The child is given assistance by trained clinicians to attempt standing and walking on the treadmill for 1 hour. The child then participates in play-based activities aimed to foster independence in an overground (regular) environment for 1 hour. The final hour of the 3-hour session is conducted in the PBWS system with a focus on standing and walking.",[9],null,{"type":6,"name":27,"description":28,"armGroupLabels":29,"otherNames":25},"physical therapy","In this intervention, the child will attend their usual physical therapy sessions.",[15],[31],{"name":32,"affiliation":5,"role":33},"Elizabeth Ardolino, PhD, PT","PRINCIPAL_INVESTIGATOR",[35,39],{"name":32,"role":36,"phone":37,"phoneExt":25,"email":38},"CONTACT","215-605-9319","liz_ardolino@baylor.edu",{"name":40,"role":36,"phone":25,"phoneExt":25,"email":41},"Megan Flores, PhD, PT","megan_flores@baylor.edu",[43],{"facility":44,"status":45,"city":46,"state":47,"zip":48,"country":49,"countryCode":50,"cosmosGeoPoint":51,"geoPoint":56,"contacts":57},"Fortis Therapy Center","RECRUITING","Dripping Springs","Texas","78620","United States","US",{"type":52,"coordinates":53},"Point",[54,55],-98.08668,30.19021,{"lat":55,"lon":54},[58,60,63],{"name":59,"role":36,"phone":37,"phoneExt":25,"email":38},"Elizabeth M Ardolino, PhD",{"name":61,"role":36,"phone":62,"phoneExt":25,"email":41},"Megan Flores, PhD","512-529-4421",{"name":59,"role":33,"phone":25,"phoneExt":25,"email":25},{"type":65,"investigatorFullName":25,"investigatorTitle":25,"investigatorAffiliation":25,"oldNameTitle":25,"oldOrganization":25},"SPONSOR",[67],{"name":68,"class":69},"Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)","NIH","100607119","activities-based-locomotor-training-in-children-with-cerebral-palsy-100607119",false,"NCT07184411","Activities-based Locomotor Training in Children With Cerebral Palsy","Efficacy of Activities-based Locomotor Training in Children With Cerebral Palsy.","ENGAGE-CP","Inclusion Criteria: To be eligible for this study, the child must be:\n\n* • Able to hold their head upright for 5 seconds when supported at the trunk in sitting (the minimal amount of head control necessary for safe walking on the partial body weight support system during the AB-LT intervention);\n\n  * Non-ambulatory or not walking as primary means of mobility;\n  * Willing to attend the AB-LT intervention at Fortis Therapy Center in Dripping Springs, Texas for 3 hours\u002F day, 5 days\u002Fweek, for 3 weeks; and\n  * Willing to commit to a total of 7 weeks of the study, and to continue their usual care during the time period in which they are not enrolled in the AB-LT intervention.\n\nExclusion Criteria: The child must not have:\n\n* • Surgery or botulinum toxin injections in the previous 6 months;\n\n  * Uncontrolled epilepsy; and\n  * Uncontrolled cardiovascular disease","ALL","2 Years","6 Years",{"count":82,"type":83},19,"ESTIMATED","INTERVENTIONAL",[86],"NA","This project aims to improve the quality of life and functional outcomes for young non-ambulatory children with Cerebral Palsy (CP) by investigating the efficacy of an Activities-Based Locomotor Training (AB-LT) program compared to usual care. By targeting the body structures, activities, and participation components of the World Health Organization's International Classification of Functioning, Disability, and Health (ICF) framework, this study seeks to enhance our understanding of neuroplasticity and motor learning in this population, offering a novel approach to rehabilitation. Results from this research will lead to more effective, individualized therapies that improve motor function, reduce disability, and ultimately lower the long-term healthcare needs associated with CP.",[89],"Cerebral Palsy (CP)",[91,92,93],"Cerebral Palsy","Locomotor Training","Physical Therapy","2025-12-01",{"date":96,"type":97},"2025-12-03","ACTUAL",{"date":99,"type":83},"2026-01-11",{"date":101,"type":83},"2028-08-31",{"name":5,"class":6},1]