[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100586066":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":24,"centralContacts":28,"locations":34,"responsibleParty":51,"collaborators":24,"id":55,"slug":56,"hasResults":57,"nctId":58,"briefTitle":59,"officialTitle":60,"acronym":24,"eligibilityCriteria":61,"healthyVolunteers":57,"sex":62,"minAge":63,"maxAge":24,"enrollmentInfo":64,"targetDuration":24,"studyType":67,"phases":68,"briefSummary":70,"conditions":71,"keywords":74,"overallStatus":37,"whyStopped":24,"lastUpdateSubmitDate":78,"lastUpdatePostDateStruct":79,"startDateStruct":82,"completionDateStruct":84,"leadSponsor":86,"locationsCount":87},{"fullName":5,"class":6},"Chinese University of Hong Kong","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Acu-TENS","EXPERIMENTAL","Acu-TENS treatment",[13],"Other: Acu-TENS",{"label":15,"type":16,"description":17,"interventionNames":18},"Sham acu-TENS","SHAM_COMPARATOR","Sham acu-TENS without electric current",[19],"Other: Sham acu-TENS",[21,25],{"type":6,"name":9,"description":22,"armGroupLabels":23,"otherNames":24},"This protocol makes use of the acu-TENS treatment on the acupoints Hegu (LI4), Zusanli (ST36), Sanyinjiao (SP6), and Taichong (LR3). After cleaning the acupoints with alcohol, electrode pads (HC-ROUND-32 2.0) will be placed on the acupoints according to the locations described in the Standard International Acupuncture Nomenclature. The electrode pads will be connected to a TENS machine (MTR+ Myolito Multifunctional Stimulator MTRP-00003), in which ipsilateral LI4 and SP36, SP6 and LR3 serve a pair. A pulse rate of 120 Hz, current of 3-5 mA, and pulse width of 300µS will be delivered continually during TUGOR.",[9],null,{"type":6,"name":15,"description":26,"armGroupLabels":27,"otherNames":24},"In the sham acu-TENS, within the same time interval, TENS pads will be placed on the same acupoints, connected to the machine, but without electric current.",[15],[29],{"name":30,"role":31,"phone":32,"phoneExt":24,"email":33},"Pui Wah Jacqueline Chung","CONTACT","+852 3505 1537","jacquelinechung@cuhk.edu.hk",[35],{"facility":36,"status":37,"city":38,"state":24,"zip":24,"country":39,"countryCode":40,"cosmosGeoPoint":41,"geoPoint":46,"contacts":47},"Chung Pui Wah, Jacqueline","RECRUITING","Hong Kong","China","CN",{"type":42,"coordinates":43},"Point",[44,45],114.17469,22.27832,{"lat":45,"lon":44},[48],{"name":49,"role":31,"phone":50,"phoneExt":24,"email":33},"Chung PW Jacqueline","35053489",{"type":52,"investigatorFullName":53,"investigatorTitle":54,"investigatorAffiliation":5,"oldNameTitle":24,"oldOrganization":24},"PRINCIPAL_INVESTIGATOR","Chung Pui Wah Jacqueline","Associate Professor (Clinical)","100586066","acu-tens-on-pain-and-stress-reduction-before-and-during-tugor-100586066",false,"NCT06910540","ACU-TENS on Pain and Stress Reduction Before and During TUGOR","Acupuncture-type Transcutaneous Electrical Nerve Stimulation on Pain and Stress Reduction Before and During Transvaginal Ultrasound-guided Oocyte Retrieval: a Randomized Controlled Trial","Inclusion Criteria:\n\n* Women undergoing IVF-ET cycles are to be recruited from the Assisted Reproduction Technology unit in the Prince of Wales Hospital\n\nExclusion Criteria:\n\n* Patient not eligible for acu-TENS\n* Patient with severe cardiac and respiratory disease history\n* Smoker or drinker\n* Refuse or incompetence for informed consent","FEMALE","18 Years",{"count":65,"type":66},144,"ESTIMATED","INTERVENTIONAL",[69],"NA","Objectives: To demonstrate the use of acupuncture-type transcutaneous electrical nerve stimulation (acu-TENS) during transvaginal ultrasound-guided oocyte retrieval (TUGOR) will reduce 50% of the intensity of pain experienced by women.\n\nHypothesis to be tested: Does the use of acu-TENS reduce 50% of pain in TUGOR? Design and subjects: A prospective randomized control trial will be carried out at the Department of Obstetrics and Gynaecology, Prince of Wales Hospital. 144 women undergoing TUGOR will be randomized to receive acu-TENS or sham acu-TENS for pain control during TUGOR.\n\nStudy instruments: During the TUGOR procedure, ultrasound of the pelvis will be performed by Aloka ProSound SSD-3500SX device (Japan). Each follicle will be pierced using a single lumen ovum aspiration needle or a double lumen ovum aspiration catheter (COOK Medical, UK) under ultrasound guidance. Acu-TENS will be done using MTR+ Myolito Multifunctional Stimulator.\n\nMain outcome measures: Primary outcome is the pain score before and during TUGOR. Secondary outcomes include (1) other pain level parameters including pain control satisfaction, surgeon's assessment of the patient co-operation score and patient intraoperative pain; (2) stress and anxiety levels, Stait Trait Anxiety Inventory, General Health Questionnaire, Beck Depression Inventory, and saliva cortisol; (3) patient's satisfaction measured by Client Satisfaction Questionnaire and satisfaction score on pain control; (4) difficulty in retrieving oocytes; (5) IVF parameters; (6) safety profile; and (7) bias assessment.\n\nData analysis: Data analysis will be performed using Statistical Packages of Social Sciences for Windows.\n\nExpected results: The investigators expect that acu-TENS will reduce 50% of pain in TUGOR.",[72,73],"Oocyte Retrieival and Post Operative Pain Control","Acupuncture",[75,76,77],"Transvaginal ultrasound-guided oocyte retrieval","Acupuncture-type transcutaneous electrical nerve stimulation","Pain control","2025-12-19",{"date":80,"type":81},"2025-12-22","ACTUAL",{"date":83,"type":81},"2025-09-01",{"date":85,"type":66},"2028-12-31",{"name":5,"class":6},1]