[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100583321":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":26,"centralContacts":31,"locations":37,"responsibleParty":57,"collaborators":26,"id":61,"slug":62,"hasResults":63,"nctId":64,"briefTitle":65,"officialTitle":66,"acronym":67,"eligibilityCriteria":68,"healthyVolunteers":63,"sex":69,"minAge":70,"maxAge":71,"enrollmentInfo":72,"targetDuration":26,"studyType":75,"phases":76,"briefSummary":78,"conditions":79,"keywords":81,"overallStatus":40,"whyStopped":26,"lastUpdateSubmitDate":87,"lastUpdatePostDateStruct":88,"startDateStruct":91,"completionDateStruct":93,"leadSponsor":95,"locationsCount":96},{"fullName":5,"class":6},"Guang'anmen Hospital of China Academy of Chinese Medical Sciences","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Acupuncture and Moxibustion Group (AM)","EXPERIMENTAL","Participants in this group will receive acupuncture and moxibustion therapy alongside standard Parkinson's disease (PD) medication. Acupuncture at Shuifen (CV9), bilateral Yinlingquan (SP9), bilateral Zhongliao (BL33), and bilateral Weiyang (BL39), combined with moxibustion at Shuifen (CV9) and Zhongliao (BL33). Each participant will undergo treatment three times per week for eight weeks (24 total sessions). Standard PD medication will remain unchanged throughout the study.",[13],"Procedure: Acupuncture and Moxibustion (AM)",{"label":15,"type":16,"description":17,"interventionNames":18},"Sham Acupuncture and Moxibustion Group (Sham-AM)","SHAM_COMPARATOR","Participants in this group will receive sham acupuncture and sham moxibustion alongside standard PD medication. Acupuncture at non-acuipoints of bilateral Hegu (LI4) and bilateral Zusanli (ST36), with fake moxibustion at Shuifen (CV9) and bilateral Zhongliao (BL33). Treatments will be conducted three times per week for eight weeks (24 total sessions). Standard PD medication will remain unchanged.",[19],"Procedure: Sham Acupuncture and Moxibustion (Sham-AM)",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"PROCEDURE","Acupuncture and Moxibustion (AM)","Acupuncture and moxibustion group (AM): Acupuncture at Shuifen (CV9), bilateral Yinlingquan (SP9), bilateral Zhongliao (BL33), and bilateral Weiyang (BL39), combined with moxibustion at Shuifen (CV9) and Zhongliao (BL33).",[9],null,{"type":22,"name":28,"description":29,"armGroupLabels":30,"otherNames":26},"Sham Acupuncture and Moxibustion (Sham-AM)","Sham acupuncture and moxibustion group (sham-AM): Acupuncture at non-acuipoints of bilateral Hegu (LI4) and bilateral Zusanli (ST36), with fake moxibustion at Shuifen (CV9) and bilateral Zhongliao (BL33).",[15],[32],{"name":33,"role":34,"phone":35,"phoneExt":26,"email":36},"Yu Liu, MD","CONTACT","8572650199","yliu133@mgh.harvard.edu",[38],{"facility":39,"status":40,"city":41,"state":42,"zip":43,"country":44,"countryCode":45,"cosmosGeoPoint":46,"geoPoint":51,"contacts":52},"Guang'anmen Hospita, China Academy of Chinese Medical Sciences","RECRUITING","Beijing","Beijing Municipality","100000","China","CN",{"type":47,"coordinates":48},"Point",[49,50],116.39723,39.9075,{"lat":50,"lon":49},[53],{"name":54,"role":34,"phone":55,"phoneExt":26,"email":56},"Jiaming Cui","86+18340077036","Jiaming.cui@foxmail.com",{"type":58,"investigatorFullName":59,"investigatorTitle":60,"investigatorAffiliation":5,"oldNameTitle":26,"oldOrganization":26},"SPONSOR_INVESTIGATOR","Jiani Wu","Associate Chief Physician","100583321","acupuncture-and-moxibustion-for-motor-symptoms-in-early-parkinsons-disease-100583321",false,"NCT06874803","Acupuncture and Moxibustion for Motor Symptoms in Early Parkinson's Disease","Effect of \"Qi-Tonifying, Yang-Warming, and Water-Resolving\" Acupuncture and Moxibustion for Motor Symptom Improvement in Early Parkinson's Disease (WARMED): A Randomized Controlled Trial","WARMED","Inclusion Criteria:\n\nParticipants must meet all of the following criteria:\n\n1\\. Diagnosed with Parkinson's disease (PD) according to the 2016 Chinese 2. Diagnostic Criteria for Parkinson's Disease.\n\n3\\. Hoehn-Yahr stage \\\u003C3 (mild to moderate PD). 4. Age between 30 and 80 years (inclusive). 5. Signed informed consent indicating voluntary participation.\n\nExclusion Criteria:\n\nParticipants meeting any of the following criteria will be excluded:\n\n1. Diagnosed with Parkinson-plus syndromes or other secondary parkinsonism.\n2. Prior history of deep brain stimulation (DBS) surgery.\n3. Severe cerebrovascular disease, brain trauma, or history of craniotomy.\n4. Severe dementia or psychiatric disorders that prevent cooperation with study procedures.\n5. Severe coagulation disorders.\n6. Presence of severe systemic organ dysfunction (cardiac, pulmonary, hepatic, renal, endocrine, or metabolic disorders).\n7. Pregnant or breastfeeding women.\n8. History of allergic reaction to acupuncture or moxibustion.\n9. Prior treatment with acupuncture or moxibustion within the past three months.\n10. Participation in another clinical trial within the past three months.","ALL","30 Years","80 Years",{"count":73,"type":74},60,"ESTIMATED","INTERVENTIONAL",[77],"NA","This study evaluates the clinical effect and safety of acupuncture combined with moxibustion in improving motor symptoms of early-stage Parkinson's Disease (PD) patients, by assessing the changes in UPDRS scores. It also explores objective factors affecting the acupuncture effect and investigates the functional MRI mechanisms of acupuncture in PD treatment.",[80],"Parkinson's Disease (PD)",[82,83,84,85,86],"Acupuncture","Moxibustion","Parkinson's Disease","Motor Symptoms","Rigidity","2025-07-16",{"date":89,"type":90},"2025-07-20","ACTUAL",{"date":92,"type":90},"2024-08-01",{"date":94,"type":74},"2026-08-31",{"name":59,"class":6},1]