[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100474662":3},{"organization":4,"armGroups":7,"interventions":25,"overallOfficials":34,"centralContacts":39,"locations":44,"responsibleParty":61,"collaborators":65,"id":67,"slug":68,"hasResults":69,"nctId":70,"briefTitle":71,"officialTitle":72,"acronym":24,"eligibilityCriteria":73,"healthyVolunteers":69,"sex":74,"minAge":75,"maxAge":76,"enrollmentInfo":77,"targetDuration":24,"studyType":80,"phases":81,"briefSummary":83,"conditions":84,"keywords":88,"overallStatus":92,"whyStopped":24,"lastUpdateSubmitDate":93,"lastUpdatePostDateStruct":94,"startDateStruct":97,"completionDateStruct":99,"leadSponsor":101,"locationsCount":102},{"fullName":5,"class":6},"Nanjing University of Traditional Chinese Medicine","OTHER",[8,14,20],{"label":9,"type":10,"description":11,"interventionNames":12},"Treatment group A","EXPERIMENTAL","Treatment group A was given endocrine and acupuncture treatment for 8 weeks (24 times in total, 3 times a week); followed up for 16 weeks, no acupuncture treatment.",[13],"Other: Acupuncture treatment",{"label":15,"type":16,"description":17,"interventionNames":18},"Treatment group B","SHAM_COMPARATOR","Treatment group B was given endocrine and sham acupuncture treatment for 8 weeks, followed up for 16 weeks, no acupuncture during the period, and after 16 weeks, received standardized acupuncture for 8 weeks (24 times in total, 3 times a week).",[19],"Other: Sham Acupuncture treatment",{"label":21,"type":22,"description":23,"interventionNames":24},"control","NO_INTERVENTION","The control group was given conventional adjuvant endocrine therapy, premenopausal patients received tamoxifen therapy, and postmenopausal patients received aromatase inhibitor or tamoxifen therapy.",null,[26,30],{"type":6,"name":27,"description":28,"armGroupLabels":29,"otherNames":24},"Acupuncture treatment","Acupoint selection: Hegu-Yinxi acupoint group (clearing heat and relieving sweat), Sanyinjiao-Fuliu acupoint group (nourishing yin and tonifying kidney), Tianshu-uteri acupoint group (special effect points) (12 acupoints on both sides).\n\nFrequency: 3 times a week (once every other day) for a total of 8 weeks of continuous treatment.\n\nOperation: Use a one-time sterile acupuncture needle (0.30×40mm, Huatuo brand), insert the needle 0.5 inch along the anatomical position, level up and relieve the qi, and keep the needle for 20 minutes.",[9],{"type":6,"name":31,"description":32,"armGroupLabels":33,"otherNames":24},"Sham Acupuncture treatment","Selecting acupoints: Select the side opening positions of the 6 acupuncture points in the real acupuncture group, and select non-meridian and non-points (points with less nerve distribution, sparseness, and rich muscles).\n\nFrequency: 3 times a week (once every other day) for a total of 8 weeks of continuous treatment.\n\nOperation: ① Shallow needling scheme: use a disposable sterile acupuncture needle, insert the needle 0.2 inch, without twisting, and keep the needle for 20 minutes. ②Non-invasive acupuncture plan: choose a special comfort needle with no needle tip at the top of the needle, paste a disposable sterile foam pad on the non-acupoint, and use a disposable sterile flat head The acupuncture needles were pierced into the foam pad, lightly touching but not piercing the skin, and not breathing; the needles were kept for 20 minutes.",[15],[35],{"name":36,"affiliation":37,"role":38},"Lijun Bai, phd","Xi'an Jiaotong University","STUDY_DIRECTOR",[40],{"name":36,"role":41,"phone":42,"phoneExt":24,"email":43},"CONTACT","0086-15129034948","bailijun@xjtu.edu.cn",[45],{"facility":46,"status":24,"city":47,"state":48,"zip":49,"country":50,"countryCode":51,"cosmosGeoPoint":52,"geoPoint":57,"contacts":58},"Jiangsu Province Hospital of Traditional Chinese Medcine","Nanjing","Jiangsu","210029","China","CN",{"type":53,"coordinates":54},"Point",[55,56],118.77778,32.06167,{"lat":56,"lon":55},[59],{"name":60,"role":41,"phone":42,"phoneExt":24,"email":43},"Lijun Bai, PHD",{"type":62,"investigatorFullName":63,"investigatorTitle":64,"investigatorAffiliation":5,"oldNameTitle":24,"oldOrganization":24},"PRINCIPAL_INVESTIGATOR","Qianyan Liu","Principal Investgator",[66],{"name":37,"class":6},"100474662","acupuncture-for-hot-flashes-in-patients-with-hormone-receptor-positive-breast-cancer-100474662",false,"NCT05460819","Acupuncture for Hot Flashes in Patients With Hormone Receptor-positive Breast Cancer.","A Randomized Controlled Trial Study of Acupuncture in the Treatment of Hot Flashes in Patients With Hormone Receptor-positive Breast Cancer.","Inclusion Criteria:\n\n* Aged 18-75 years old;\n* Adjuvant hormone therapy (eg, tamoxifen and\u002For aromatase inhibitors) with or without ovarian function suppression has been administered for at least 4 weeks and is currently on treatment;\n* Vasomotor syndrome for at least 6 weeks;\n* Premenopausal or postmenopausal patients;\n* Patients with persistent hot flashes for at least 4 weeks and with a frequency of more than 14 hot flashes per week (2 times per day) in the week before inclusion in the study, the weekly average hot flash composite score is 3-4;\n* Patients after surgery and after chemotherapy (if any);\n* Eastern Cooperative Oncology Group score of 0-1 points.\n* Sign the informed consent and voluntarily participate in this clinical observation.\n\nExclusion Criteria:\n\n* Tumor metastases, undergoing chemoradiotherapy or planning surgery;\n* Pharmacological intervention for hot flashes with hot flash treatment drugs such as selective serotonin reuptake inhibitors (SSRIs) and\u002For anticonvulsants for at least 4 weeks prior to study initiation;\n* Unstable heart disease or myocardial infarction within 6 months prior to study start;\n* Started or changed adjuvant hormone therapy within the past week, or who planned to start or change adjuvant hormone therapy in the past 14 weeks;\n* Seizures of unknown likelihood or history of seizures;\n* Have used acupuncture for hot flashes within 6 months prior to the start of the study;\n* Pregnant or breastfeeding patients;\n* Apparent uncontrolled infection;\n* Mental illness or family history; neurological disorder or family history.","FEMALE","18 Years","75 Years",{"count":78,"type":79},90,"ESTIMATED","INTERVENTIONAL",[82],"NA","This study intends to further evaluate the efficacy of acupuncture by comparing the intervention effects of different acupuncture treatment regimens on hot flashes in breast cancer ; and to explore the central effect regulation mechanism of acupuncture intervention on hot flashes based on functional magnetic resonance imaging technology.",[85,86,87],"Hot Flashes","Breast Cancer","Acupuncture",[89,87,90,91],"breast cancer","hot flashes","Functional MRI","NOT_YET_RECRUITING","2022-07-19",{"date":95,"type":96},"2022-07-20","ACTUAL",{"date":98,"type":79},"2022-08-01",{"date":100,"type":79},"2027-07-31",{"name":5,"class":6},1]