[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100572853":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":25,"centralContacts":30,"locations":36,"responsibleParty":52,"collaborators":25,"id":56,"slug":57,"hasResults":58,"nctId":59,"briefTitle":60,"officialTitle":61,"acronym":25,"eligibilityCriteria":62,"healthyVolunteers":63,"sex":64,"minAge":65,"maxAge":66,"enrollmentInfo":67,"targetDuration":25,"studyType":70,"phases":71,"briefSummary":73,"conditions":74,"keywords":76,"overallStatus":81,"whyStopped":25,"lastUpdateSubmitDate":82,"lastUpdatePostDateStruct":83,"startDateStruct":86,"completionDateStruct":88,"leadSponsor":90,"locationsCount":91},{"fullName":5,"class":6},"Beijing Hospital of Traditional Chinese Medicine","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"acupuncture","EXPERIMENTAL","Patients in the acupuncture group will receive treatment at specified acupoints, performed by acupuncturists with at least five years of experience. The acupoints include bilateral Hegu (LI4), Yanglingquan (GB34), and affected-side Jiache (ST6), Xiaguan (ST7), and Tinggong (SI19).",[13],"Other: Acupuncture",{"label":15,"type":16,"description":17,"interventionNames":18},"sham acupuncture","SHAM_COMPARATOR","Patients in the sham group will receive noninvasive acupuncture at the same acupoints as the acupuncture group. Sham needles, which resemble real needles but are blunt and slide within their handles, will be applied using the Park Sham device, secured to the skin with a self-adhesive pad. The procedure of manipulation is the same as for acupuncture, but without Deqi.",[19],"Other: Sham treatment",[21,26],{"type":6,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"Acupuncture","Patients in the acupuncture group will receive treatment at specified acupoints, performed by acupuncturists with at least five years of experience. The acupoints include bilateral Hegu (LI4), Yanglingquan (GB34), and affected-side Jiache (ST6), Xiaguan (ST7), and Tinggong (SI19). Participants will lie supine, and the skin will be sterilized. Sterile stainless-steel needles (0.25 mm diameter, 40 mm length) will be inserted using a guide device and a self-adhesive pad. Needles will be manipulated for at least 10 seconds to induce Deqi. Participants will receive 30 minutes of acupuncture for twelve sessions (3 per week for 4 weeks).",[9],null,{"type":6,"name":27,"description":28,"armGroupLabels":29,"otherNames":25},"Sham treatment","The Park Sham device will be used for the sham acupuncture group. To maintain blinding, the acupuncture ritual will be identical in both groups, with the following exceptions: patients in the sham group will receive noninvasive acupuncture at the same acupoints as the acupuncture group. Sham needles, which resemble real needles but are blunt and slide within their handles, will be applied using the Park Sham device, secured to the skin with a self-adhesive pad. The procedure of manipulation is the same as for acupuncture, but without Deqi.",[15],[31],{"name":32,"role":33,"phone":34,"phoneExt":25,"email":35},"Bin Li, Dr","CONTACT","0086-18910781852","libin@bjzhongyi.com",[37],{"facility":5,"status":25,"city":38,"state":39,"zip":40,"country":41,"countryCode":42,"cosmosGeoPoint":43,"geoPoint":48,"contacts":49},"Beijing","Beijing Municipality","100010","China","CN",{"type":44,"coordinates":45},"Point",[46,47],116.39723,39.9075,{"lat":47,"lon":46},[50],{"name":51,"role":33,"phone":34,"phoneExt":25,"email":35},"Bin Li, MD",{"type":53,"investigatorFullName":54,"investigatorTitle":55,"investigatorAffiliation":5,"oldNameTitle":25,"oldOrganization":25},"PRINCIPAL_INVESTIGATOR","Li bin","Professor","100572853","acupuncture-for-painful-temporomandibular-disorder-100572853",false,"NCT06738667","Acupuncture for Painful Temporomandibular Disorder","Study on Imaging Characteristics and Predictive Radiology of Brain Network Regulation by Acupuncture in Patients with Painful Temporomandibular Disorders","Inclusion Criteria:\n\n1. Having a history of pain-related TMD for at least three months;\n2. Aged between 18 and 70 years;\n3. Voluntary participation in the trial with signed informed consent.\n\nExclusion Criteria:\n\n1. Having received occlusal splint, injection therapy, acupuncture, biofeedback, transcutaneous nerve stimulation, or TMD-specific medication (e.g., corticosteroids, benzodiazepines, sedative hypnotics, muscle relaxants, opioids, antidepressants, or anticonvulsants) for managing facial pain within one month before the screening period;\n2. Having suffered from pain of dental origin, trauma, sinus pathology, neuropathic origin, inflammatory systemic diseases and cancer;\n3. Having a history of rheumatoid arthritis;\n4. Presence of mental illness or substance abuse;\n5. Pregnant, lactating, or planning to become pregnant;\n6. Participants with common contra-indications for MRI such as claustrophobia or metal implants.",true,"ALL","18 Years","70 Years",{"count":68,"type":69},48,"ESTIMATED","INTERVENTIONAL",[72],"NA","Temporomandibular disorder (TMD) is a common musculoskeletal pain condition affecting the jaw, and acupuncture is often used for treatment, though its neurological mechanisms are unclear. This study investigates the neural mechanisms of acupuncture in TMD using functional MRI (fMRI), structural MRI (sMRI), and diffusion tensor imaging (DTI), alongside machine learning to predict treatment outcomes. This study aims to enhance understanding of acupuncture's effects on TMD and improve personalized treatment approaches.",[75],"Temporomandibular Disorders (TMD)",[77,22,78,79,80],"Temporomandibular disorders","Magnetic resonance imaging","Randomized controlled trial","Protocol","NOT_YET_RECRUITING","2024-12-13",{"date":84,"type":85},"2024-12-18","ACTUAL",{"date":87,"type":69},"2025-06-01",{"date":89,"type":69},"2026-12-31",{"name":5,"class":6},1]