[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100563407":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":25,"centralContacts":29,"locations":25,"responsibleParty":35,"collaborators":25,"id":39,"slug":40,"hasResults":41,"nctId":42,"briefTitle":43,"officialTitle":44,"acronym":25,"eligibilityCriteria":45,"healthyVolunteers":41,"sex":46,"minAge":47,"maxAge":48,"enrollmentInfo":49,"targetDuration":25,"studyType":52,"phases":53,"briefSummary":55,"conditions":56,"keywords":58,"overallStatus":63,"whyStopped":25,"lastUpdateSubmitDate":64,"lastUpdatePostDateStruct":65,"startDateStruct":68,"completionDateStruct":70,"leadSponsor":72,"locationsCount":25},{"fullName":5,"class":6},"Guang'anmen Hospital of China Academy of Chinese Medical Sciences","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Acupuncture group","EXPERIMENTAL","Acupuncture sessions will use sterile, disposable stainless-steel needles (0.3 mm × 40 mm and 0.3 mm × 75 mm). Each session has two phases:\n\nSupine Position:\n\nNeedles (0.35 mm × 75 mm) are inserted into ST25, ST15, and SP14, reaching the abdominal muscle layer.\n\nNeedles (0.30 mm × 40 mm) are inserted into CV12, CV4, ST36, ST37, and SP6. Electroacupuncture (EA) at ST25, SP15, and ST36 uses a continuous 5 Hz wave, 0.1 to 2.0 mA.\n\nProne Position:\n\nNeedles are inserted into BL32, BL33, and BL35 with precise angles and depths. EA at BL32, BL33, and BL35 uses a continuous 5 Hz wave, 2.0 to 6.5 mA. Sessions occur three times a week for the first 4 weeks, then twice a week for weeks 5 to 8, each lasting 40 minutes, totaling 20 sessions.",[13],"Other: Acupuncture",{"label":15,"type":16,"description":17,"interventionNames":18},"Sham acupuncture group","SHAM_COMPARATOR","Sterile, disposable stainless-steel needles (0.30 mm × 25 mm) will be used. After skin sterilization, needles will be inserted into the same points as the acupuncture group but to a shallow depth of 2 to 3 mm and lightly manipulated for blinding. Paired alligator clips will be attached to the same points, but the sham EA apparatus will have no current output, though it mimics the active EA apparatus in appearance and sound. Sham sessions will follow the same schedule as the acupuncture group: three times a week for the first 4 weeks and twice a week for weeks 5 to 8, each lasting 40 minutes, totaling 20 sessions.",[19],"Other: Sham acupuncture",[21,26],{"type":6,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"Acupuncture","Acupuncture sessions will use sterile, disposable stainless-steel needles (0.3 mm × 40 mm and 0.3 mm × 75 mm). Each session has two phases:\n\nSupine Position:\n\n* Needles (0.35 mm × 75 mm) are inserted into ST25, ST15, and SP14, reaching the abdominal muscle layer.\n* Needles (0.30 mm × 40 mm) are inserted into CV12, CV4, ST36, ST37, and SP6.\n* Electroacupuncture (EA) at ST25, SP15, and ST36 uses a continuous 5 Hz wave, 0.1 to 2.0 mA.\n\nProne Position:\n\n* Needles are inserted into BL32, BL33, and BL35 with precise angles and depths.\n* EA at BL32, BL33, and BL35 uses a continuous 5 Hz wave, 2.0 to 6.5 mA. Sessions occur three times a week for the first 4 weeks, then twice a week for weeks 5 to 8, each lasting 40 minutes, totaling 20 sessions.",[9],null,{"type":6,"name":27,"description":17,"armGroupLabels":28,"otherNames":25},"Sham acupuncture",[15],[30],{"name":31,"role":32,"phone":33,"phoneExt":25,"email":34},"He Chen, bachelor of medicine","CONTACT","+86 19927523321","chenhenick@gmail.com",{"type":36,"investigatorFullName":37,"investigatorTitle":38,"investigatorAffiliation":5,"oldNameTitle":25,"oldOrganization":25},"PRINCIPAL_INVESTIGATOR","He Chen","Researcher, Department of Acupuncture, Guang'anmen Hospital, China Academy of Chinese Medical Sciences, Principal Investigator","100563407","acupuncture-for-symptom-relief-in-adults-with-mild-to-moderate-ulcerative-colitis-100563407",false,"NCT06615765","Acupuncture for Symptom Relief in Adults with Mild to Moderate Ulcerative Colitis","Efficacy and Safety of Two-step Acupuncture Therapy for Symptom Relief in Adults with Mild to Moderate Ulcerative Colitis","Inclusion Criteria:\n\nEligible participants are those aged 18 to 70 years who meet the diagnostic criteria for mild to moderate UC, have a PRO2 score of ≥ 2 points, and provide written informed consent. Patients currently receiving oral and\u002For topical 5-aminosalicylic acid (such as mesalamine) may continue their treatment during the study period.\n\nExclusion Criteria:\n\nParticipants will be excluded if they meet any of the following criteria:\n\n1. Diagnosis of Crohn's disease, intestinal tuberculosis, chronic intestinal infections, or intestinal malignancies.\n2. Current treatment with corticosteroids, thiopurines, biologics, or oral small molecules.\n3. Severe skin conditions or infections.\n4. Presence of severe underlying medical conditions, including but not limited to cardiovascular diseases, hepatobiliary diseases, kidney diseases, hematologic disorders, autoimmune diseases, communicable diseases, severe malnutrition, or malignancies.\n5. Mental illness, cognitive dysfunction, or language disorders.\n6. Receipt of acupuncture therapy for UC within the past month.\n7. Substance abuse issues.\n8. Pregnancy, plans to become pregnant within the next year, lactation, or being within 12 months postpartum.","ALL","18 Years","70 Years",{"count":50,"type":51},64,"ESTIMATED","INTERVENTIONAL",[54],"NA","Ulcerative colitis (UC) is one of the two primary forms of inflammatory bowel disease. This condition is characterized by continuous mucosal inflammation that begins in the rectum and extends proximally throughout the colon. Common intestinal symptoms also include rectal bleeding, increased stool frequency, tenesmus, nocturnal bowel movements, and crampy abdominal pain. Acupuncture has been suggested as a potential intervention to alleviate clinical symptoms of UC. This single-center, parallel-group, two-arm, randomized, sham-controlled trial aims to evaluate the effects and safety of acupuncture for UC.",[57],"Ulcerative Colitis",[22,59,60,61,62],"Ulcerative colitis","Patient-reported outcome 2","Inflammatory bowel disease","Randomized controlled trial","NOT_YET_RECRUITING","2024-09-24",{"date":66,"type":67},"2024-09-27","ACTUAL",{"date":69,"type":51},"2024-11-01",{"date":71,"type":51},"2026-10-31",{"name":5,"class":6}]