[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100614095":3},{"organization":4,"armGroups":7,"interventions":28,"overallOfficials":40,"centralContacts":41,"locations":47,"responsibleParty":83,"collaborators":85,"id":93,"slug":94,"hasResults":95,"nctId":96,"briefTitle":97,"officialTitle":98,"acronym":40,"eligibilityCriteria":99,"healthyVolunteers":95,"sex":100,"minAge":101,"maxAge":102,"enrollmentInfo":103,"targetDuration":40,"studyType":106,"phases":107,"briefSummary":109,"conditions":110,"keywords":112,"overallStatus":139,"whyStopped":40,"lastUpdateSubmitDate":140,"lastUpdatePostDateStruct":141,"startDateStruct":144,"completionDateStruct":146,"leadSponsor":148,"locationsCount":149},{"fullName":5,"class":6},"Universidade da Coruña","OTHER",[8,14,18,23],{"label":9,"type":10,"description":11,"interventionNames":12},"BFR40%","EXPERIMENTAL","BFR set at 40% of the participant's arterial occlusion pressure (AOP).",[13],"Behavioral: Walking",{"label":15,"type":10,"description":16,"interventionNames":17},"BFR80%","BFR set at 80% of the participant's AOP.",[13],{"label":19,"type":20,"description":21,"interventionNames":22},"BFR0%","SHAM_COMPARATOR","BFR set at 0% of the participant's AOP.",[13],{"label":24,"type":25,"description":26,"interventionNames":27},"CON","ACTIVE_COMPARATOR","No BFR cuffs.",[13],[29],{"type":30,"name":31,"description":32,"armGroupLabels":33,"otherNames":34},"BEHAVIORAL","Walking","Participants will perform two continuous 10-minute walking bouts, separated by a 3-minute seated recovery period to allow reperfusion following BFR or pause, along a rectangular 40-meter walking circuit (15×5 m). Walking cadence will be standardized at 112 steps per minute.",[19,9,15,24],[35,36,37,38,39],"Physical activity","Aerobic exercise","Cardio exercise","Endurance exercise","Functional movement",null,[42],{"name":43,"role":44,"phone":45,"phoneExt":40,"email":46},"Marta Sevilla-Sanchez, Postdoctoral research","CONTACT","34 637 235 257","marta.sevilla@udc.es",[48,66],{"facility":49,"status":40,"city":50,"state":51,"zip":52,"country":53,"countryCode":54,"cosmosGeoPoint":55,"geoPoint":60,"contacts":61},"Faculty of Sport of University of Porto","Porto","Porto District","4200-450","Portugal","PT",{"type":56,"coordinates":57},"Point",[58,59],-8.61097,41.1485,{"lat":59,"lon":58},[62],{"name":63,"role":44,"phone":64,"phoneExt":40,"email":65},"Lucimere Bohn, Researcher","351 917 028 600","lucimerebohn@fade.up.pt",{"facility":67,"status":40,"city":68,"state":69,"zip":70,"country":71,"countryCode":72,"cosmosGeoPoint":73,"geoPoint":77,"contacts":78},"Faculty of Education of University of La Laguna","San Cristóbal de La Laguna","Santa Cruz de Tenerife","38204","Spain","ES",{"type":56,"coordinates":74},[75,76],-16.32014,28.4853,{"lat":76,"lon":75},[79],{"name":80,"role":44,"phone":81,"phoneExt":40,"email":82},"Eduardo Carballeira, PhD","0034-634-476-577","ecarball@ull.edu.es",{"type":84,"investigatorFullName":40,"investigatorTitle":40,"investigatorAffiliation":40,"oldNameTitle":40,"oldOrganization":40},"SPONSOR",[86,89,91],{"name":87,"class":88},"Ministry of Work and Welfare - Xunta de Galicia","OTHER_GOV",{"name":90,"class":6},"Universidade do Porto",{"name":92,"class":6},"University of La Laguna","100614095","acute-cardiovascular-and-neuromuscular-responses-to-walking-with-blood-flow-restriction-bfr-in-older-adults-100614095",false,"NCT07275138","Acute Cardiovascular and Neuromuscular Responses to Walking With Blood Flow Restriction (BFR) in Older Adults","Acute Cardiovascular and Neuromuscular Responses to Walking With Blood Flow Restriction in Older Adults: a Study Protocol for a Randomized Crossover Trial","Inclusion Criteria:\n\n• Aged between 60 and 90 years.\n\nExclusion Criteria:\n\n* Being institutionalized.\n* Peripheral vascular disease, defined by an ankle-brachial index (ABI) outside the normal range (0.9-1.4).\n* Uncontrolled arterial hypertension (\\>180\u002F110 mmHg).\n* Any contraindication to exercise, based on self-reported medical history and PAR-Q+.","ALL","60 Years","90 Years",{"count":104,"type":105},20,"ESTIMATED","INTERVENTIONAL",[108],"NA","The goal of this clinical trial is to explore how walking combined with different levels of partial blood flow restriction (BFR) affects cardiovascular, neuromuscular, and movement (kinematic) variables in older adults.\n\nThe main questions it aims to answer are:\n\nDoes walking with BFR increase internal effort, as shown by cardiovascular changes, and is this effect proportional to the level of restriction?\n\nDoes walking with BFR temporarily reduce neuromuscular control, and is this reduction greater at higher restriction levels?\n\nDoes walking with BFR change gait movement patterns?\n\nThis study uses a crossover design, meaning that each participant will complete all four conditions and serve as their own control.\n\nParticipants will:\n\nTake part in walking sessions under four conditions with different levels of restriction: BFR40%, BFR80%, SHAM (0% BFR), and CON (without BFR).\n\nHave their cardiovascular responses, muscle performance, and gait movement patterns measured.\n\nReport their perceptions of the sessions, including Rate of Perceived Exertion (RPE), satisfaction, and possible side effects.",[111],"Healthy Older Adults",[113,114,115,116,117,118,119,120,121,122,123,36,35,124,125,126,127,128,129,130,131,132,133,134,135,136,137,138],"Blood Flow Restriction (BFR)","walking exercise","older adults","Gait Kinematic","Cardiovascular Response","Neuromuscular Performance","Crossover Study","Physical Function","safety","Endurance training","Low-impact exercise","functionality","Elderly","Senior","Age 60+","Community-dwelling","Non-institutionalized","Partial Blood Flow Restriction","Limb Occlusion Training","Vascular Occlusion Training","KAATSU Training","Low-load resistance training with BFR","Occlusion exercise","walking","walking training","exercise training","NOT_YET_RECRUITING","2025-11-28",{"date":142,"type":143},"2025-12-10","ACTUAL",{"date":145,"type":105},"2025-12-08",{"date":147,"type":105},"2026-01",{"name":5,"class":6},2]