[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100568244":3},{"organization":4,"armGroups":7,"interventions":30,"overallOfficials":36,"centralContacts":36,"locations":49,"responsibleParty":70,"collaborators":74,"id":78,"slug":79,"hasResults":80,"nctId":81,"briefTitle":82,"officialTitle":83,"acronym":36,"eligibilityCriteria":84,"healthyVolunteers":80,"sex":85,"minAge":86,"maxAge":87,"enrollmentInfo":88,"targetDuration":36,"studyType":91,"phases":92,"briefSummary":94,"conditions":95,"keywords":97,"overallStatus":52,"whyStopped":36,"lastUpdateSubmitDate":101,"lastUpdatePostDateStruct":102,"startDateStruct":105,"completionDateStruct":107,"leadSponsor":109,"locationsCount":110},{"fullName":5,"class":6},"Universidade Federal de Sao Carlos","OTHER",[8,14,20,25],{"label":9,"type":10,"description":11,"interventionNames":12},"Panel Group","EXPERIMENTAL","Participants who will receive full-body photobiomodulation irradiation, from a panel of LEDs",[13],"Device: Panel Effective Photobiomodulation Therapy",{"label":15,"type":16,"description":17,"interventionNames":18},"Panel Sham Group","SHAM_COMPARATOR","Participants who will receive full-body photobiomodulation irradiation, with the device turned-off",[19],"Device: Sham Panel Photobiomodulation Therapy",{"label":21,"type":10,"description":22,"interventionNames":23},"Modified ILIB Group","Participants who will receive photobiomodulation irradiation with the transcutaneous ILIB method",[24],"Device: Modified ILIB Photobiomodulation Therapy",{"label":26,"type":16,"description":27,"interventionNames":28},"Modified ILIB Sham Group","Participants who will received photobiomodulation irradiation with the transcutaneous ILIB method, with the device turned-off",[29],"Device: Modified ILIB Sham Photobiomodulation Therapy",[31,37,41,45],{"type":32,"name":33,"description":34,"armGroupLabels":35,"otherNames":36},"DEVICE","Panel Effective Photobiomodulation Therapy","Photobiomodulation therapy is the use of low-power light in biological tissues through a non-ionizing source of light (600 to 1.100 nm), with variable power between 1 and 500 mW and therapeutic goals.\n\nThis group will receive photobiomodulation from a whole-body panel of low intensity LEDs",[9],null,{"type":32,"name":38,"description":39,"armGroupLabels":40,"otherNames":36},"Sham Panel Photobiomodulation Therapy","Use of common red lamp to perform the sham photobiomodulation for the panel group",[15],{"type":32,"name":42,"description":43,"armGroupLabels":44,"otherNames":36},"Modified ILIB Sham Photobiomodulation Therapy","ILIB Therapy device turned off for the sham ILIB therapy",[26],{"type":32,"name":46,"description":47,"armGroupLabels":48,"otherNames":36},"Modified ILIB Photobiomodulation Therapy","Common laser used in ILIB mode for modified ILIB therapy",[21],[50],{"facility":51,"status":52,"city":53,"state":54,"zip":55,"country":56,"countryCode":57,"cosmosGeoPoint":58,"geoPoint":63,"contacts":64},"Federal University of São Carlos","RECRUITING","São Carlos","São Paulo","13565-905","Brazil","BR",{"type":59,"coordinates":60},"Point",[61,62],-47.89083,-22.0175,{"lat":62,"lon":61},[65],{"name":66,"role":67,"phone":68,"phoneExt":36,"email":69},"Lara Espósito, PT","CONTACT","+551633518985","larabataglia@estudante.ufscar.br",{"type":71,"investigatorFullName":72,"investigatorTitle":73,"investigatorAffiliation":5,"oldNameTitle":36,"oldOrganization":36},"PRINCIPAL_INVESTIGATOR","Lara Maria Bataglia Espósito","Physical Therapist, Master's student",[75],{"name":76,"class":77},"Fundação de Amparo à Pesquisa do Estado de São Paulo","OTHER_GOV","100568244","acute-effect-of-photobiomodulation-in-individuals-with-hypertension-100568244",false,"NCT06678698","Acute Effect of Photobiomodulation in Individuals with Hypertension","Acute Effect of Photobiomodulation on Blood Pressure, Endothelial Function and Arterial Stiffness in Individuals with Hypertension: a Randomized Controlled Trial","Inclusion Criteria:\n\n* Sedentary or irregularly inactive individuals (IPAQ)\n* Both sexes\n* Age between 40 to 60 years old\n* Clinical diagnosis of hypertension for at least 3 months with difficulty in blood pressure control\n* Hypertension classification up to stage 2\n* Individuals who have a prescription for hypertension control drugs and have been using these drugs for at least 3 months\n\nExclusion Criteria:\n\n* Diabetes diagnosis\n* Smokers\n* BMI \\> 30 kg\u002Fm²\n* Cardiac pacemaker use\n* Presence of arrhythmias or other decompensated cardiovascular diseases\n* Musculoskeletal, orthopedic or neurological conditions that make it unable to participate in the procedures\n* Presence of cognitive deficits that make it difficult to understand the assessments\n* Presence of active neoplasia, under suspicion or after 5 years in remission period\n* Presence of tattoos (covering a large body area, or the anterior wrist region)\n* Photosensitive drugs use\n* Pregnant women or under suspicion\n* Presence of epilepsy or seizures\n* Participants who present a systolic blood pressure ≥ 180 mmHg and\u002For diastolic blood pressure ≥ 110 mmHg on the day of the intervention","ALL","40 Years","60 Years",{"count":89,"type":90},48,"ESTIMATED","INTERVENTIONAL",[93],"NA","This is a randomized, double-blind and sham-controlled clinical trial that aims to evaluate and compare the acute effect of full-body photobiomodulation (PBM) and modified ILIB (Intravascular laser irradiation of blood) on blood pressure, endothelial function and arterial stiffness in individuals with hypertension. Participants (n=48) will be equally, randomly and secretly allocated into one of 4 groups: Panel Group; Panel Sham Group; Modified ILIB group; and Modified ILIB Sham Group. Participants aged 40 to 60 years old, diagnosed with hypertension and using control drugs for at least 3 months will be included. Participants will be assessed at pre- and post-intervention for: BP; endothelial function; arterial stiffness; blood nitrite; and thermography. In the post-intervention period, the ambulatory blood pressure monitoring will also be carried out. Participants will receive a single application of PBM, which, depending on the group, may be full-body irradiation from an LED panel (660 nm; 25.34 J\u002Fcm²; 42.24 mW\u002Fcm²), modified ILIB (660 nm; 42,462 J\u002Fcm²; 35.385 W\u002Fcm²), or the respective sham therapies. Data homogeneity and normality will be verified by the Levene and Shapiro-Wilk tests, which will determine the choice of subsequent tests. A statistical significance of 5% will be considered.",[96],"Hypertension",[98,99,100],"hypertension","photobiomodulation","low-level light therapy","2024-11-06",{"date":103,"type":104},"2024-11-08","ACTUAL",{"date":106,"type":104},"2024-05-01",{"date":108,"type":90},"2025-01-30",{"name":5,"class":6},1]