[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100458200":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":26,"centralContacts":31,"locations":37,"responsibleParty":55,"collaborators":26,"id":59,"slug":60,"hasResults":61,"nctId":62,"briefTitle":63,"officialTitle":63,"acronym":26,"eligibilityCriteria":64,"healthyVolunteers":65,"sex":66,"minAge":67,"maxAge":68,"enrollmentInfo":69,"targetDuration":26,"studyType":72,"phases":73,"briefSummary":75,"conditions":76,"keywords":26,"overallStatus":40,"whyStopped":26,"lastUpdateSubmitDate":78,"lastUpdatePostDateStruct":79,"startDateStruct":82,"completionDateStruct":84,"leadSponsor":86,"locationsCount":87},{"fullName":5,"class":6},"University Hospital, Bonn","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Exercise","EXPERIMENTAL","30 min of cycling on a stationary ergometer, guided by a video of a professional cycling instructor.\n\n* Half of the patients (n=30) and their respective matched healthy controls (n=30) will perform moderate-intensity exercise: continuous cycling at 64-76% of the individual HRmax).\n* The other half will perform a high-intensity interval training (HIIT) protocol: 5 min warm-up phase, followed by bursts of high-intensity cycling interspersed with varied recovery times (21 min in total), 4 min cool-down. Excluding warm-up and cool-down, intensities will remain \\>77% of individual HRmax during the whole routine.\n\nHeart rate will be continuously recorded using a chest strap heart rate monitor and monitored by the patients themselves and the experimenter.",[13],"Behavioral: Physical Exercise",{"label":15,"type":16,"description":17,"interventionNames":18},"Control condition","ACTIVE_COMPARATOR","30 min of watching a documentary about the benefits of physical activity on health. Heart rate will be recorded also during the control condition.",[19],"Behavioral: Control Intervention",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"BEHAVIORAL","Physical Exercise","30 min of cycling on an ergometer, moderate or high intensity",[9],null,{"type":22,"name":28,"description":29,"armGroupLabels":30,"otherNames":26},"Control Intervention","30 min of watching a movie",[15],[32],{"name":33,"role":34,"phone":35,"phoneExt":26,"email":36},"Aylin Mehren, Dr.","CONTACT","+4922828731370","aylin.mehren@ukbonn.de",[38],{"facility":39,"status":40,"city":41,"state":42,"zip":43,"country":44,"countryCode":45,"cosmosGeoPoint":46,"geoPoint":51,"contacts":52},"University Hospital Bonn","RECRUITING","Bonn","North Rhine-Westphalia","53127","Germany","DE",{"type":47,"coordinates":48},"Point",[49,50],7.09549,50.73438,{"lat":50,"lon":49},[53],{"name":33,"role":34,"phone":54,"phoneExt":26,"email":36},"+22828731370",{"type":56,"investigatorFullName":57,"investigatorTitle":58,"investigatorAffiliation":5,"oldNameTitle":26,"oldOrganization":26},"PRINCIPAL_INVESTIGATOR","Aylin Mehren","Dr., Principal Investigator","100458200","acute-effects-of-physical-exercise-in-patients-with-borderline-personality-disorder-100458200",false,"NCT05246527","Acute Effects of Physical Exercise in Patients with Borderline Personality Disorder","Inclusion Criteria:\n\n* estimated verbal intelligence quotient \\>80 (MWT-B; Lehrl 2005)\n* patients: diagnosis of borderline personality disorder according to DSM-5\n\nExclusion Criteria:\n\n* neurological disorders\n* health conditions interfering with exercise safety, e.g. coronary heart disease\n* visual impairments that may interfere with performance of the cognitive tasks\n* endocrine disorders, e.g. hyperthyreosis or diabetes mellitus;\n* following psychiatric disorders: psychosis or affective disorders with psychotic symptoms, schizophrenia, substance abuse or dependence, autism spectrum disorders, anorexia nervosa;\n* healthy controls: BPD, intake of psychotropic drugs",true,"ALL","18 Years","50 Years",{"count":70,"type":71},120,"ESTIMATED","INTERVENTIONAL",[74],"NA","The aim of the proposed project is to investigate the effects of a single session of physical exercise on stress regulation, cognitive and emotional functioning, and associated neurophysiological processes (saliva and blood samples) in patients with borderline personality disorder. A further aim is to identify the optimal exercise intensity (moderate vs. high intensity). The investigatiors expect that acute exercise will lead to positive effects on behavioral and biomarker level.",[77],"Borderline Personality Disorder","2024-12-06",{"date":80,"type":81},"2024-12-11","ACTUAL",{"date":83,"type":81},"2022-02-08",{"date":85,"type":71},"2025-12-31",{"name":5,"class":6},1]