[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100643768":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":10,"centralContacts":10,"locations":19,"responsibleParty":31,"collaborators":10,"id":35,"slug":36,"hasResults":37,"nctId":38,"briefTitle":39,"officialTitle":40,"acronym":10,"eligibilityCriteria":41,"healthyVolunteers":37,"sex":42,"minAge":43,"maxAge":10,"enrollmentInfo":44,"targetDuration":10,"studyType":47,"phases":10,"briefSummary":48,"conditions":49,"keywords":52,"overallStatus":61,"whyStopped":10,"lastUpdateSubmitDate":62,"lastUpdatePostDateStruct":63,"startDateStruct":66,"completionDateStruct":68,"leadSponsor":70,"locationsCount":71},{"fullName":5,"class":6},"Sohag University","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Patients with Acute Upper Gastrointestinal Bleeding",null,"Adult patients (≥18 years) presenting with acute upper gastrointestinal bleeding (UGIB) and admitted to Sohag University Hospitals. Patients will be followed prospectively to assess the incidence of acute kidney injury (AKI) and its predictors.",[13],"Other: Observational assessment",[15],{"type":6,"name":16,"description":17,"armGroupLabels":18,"otherNames":10},"Observational assessment","No therapeutic intervention is applied. Patients are managed according to standard hospital care, and data are collected observationally.",[9],[20],{"facility":21,"status":10,"city":22,"state":10,"zip":10,"country":23,"countryCode":24,"cosmosGeoPoint":25,"geoPoint":30,"contacts":10},"Sohag University Hospitals","Sohag","Egypt","EG",{"type":26,"coordinates":27},"Point",[28,29],31.69478,26.55695,{"lat":29,"lon":28},{"type":32,"investigatorFullName":33,"investigatorTitle":34,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"PRINCIPAL_INVESTIGATOR","Walaa Abdelrahim Abdelfattah","Resident of Internal Medicine","100643768","acute-kidney-injury-in-upper-gi-bleeding-patients-100643768",false,"NCT07636083","Acute Kidney Injury in Upper GI Bleeding Patients","Acute Kidney Injury Following Upper Gastrointestinal Bleeding: Incidence and Predictors","Inclusion Criteria:\n\n* Adult patients aged 18 years or older\n* Patients presenting with clinical features suggestive of acute upper gastrointestinal bleeding (UGIB), including hematemesis, coffee-ground vomiting, or melena\n* Diagnosis of UGIB confirmed by upper gastrointestinal endoscopy or strong clinical evidence when endoscopy is not immediately available\n* Patients admitted to Sohag University Hospitals (medical wards or intensive care unit)\n* Availability of renal function data, including at least one serum creatinine measurement at admission and serial measurements during hospitalization\n* Availability of baseline renal function (previous serum creatinine within 3-12 months) or estimable baseline during hospitalization\n\nExclusion Criteria:\n\n* Patients with end-stage renal disease (ESRD) on chronic dialysis\n* Patients with a history of renal transplantation\n* Patients with advanced chronic kidney disease stage 5 (eGFR \\\u003C15 mL\u002Fmin\u002F1.73 m²) not on dialysis\n* Patients with lower gastrointestinal bleeding\n* Patients with incomplete or missing essential renal function data\n* Patients discharged or deceased within 24 hours of hospital admission\n* Pregnant patients\n* Patients with acute kidney injury at presentation due to causes other than UGIB","ALL","18 Years",{"count":45,"type":46},200,"ESTIMATED","OBSERVATIONAL","This study aims to evaluate the incidence of acute kidney injury (AKI) among patients presenting with acute upper gastrointestinal bleeding (UGIB) at Sohag University Hospitals, and to identify predictors associated with renal impairment in these patients.",[50,51],"Upper Gastrointestinal Bleeding","Acute Kidney Injury",[53,54,55,56,57,58,59,60],"UGIB","AKI","Renal Impairment","Gastrointestinal Hemorrhage","Serum Creatinine","Kidney Function","Variceal Bleeding","Non-variceal Bleeding","NOT_YET_RECRUITING","2026-06-04",{"date":64,"type":65},"2026-06-09","ACTUAL",{"date":67,"type":46},"2026-05-15",{"date":69,"type":46},"2027-05-15",{"name":5,"class":6},1]