[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100633108":3},{"organization":4,"armGroups":7,"interventions":22,"overallOfficials":31,"centralContacts":38,"locations":48,"responsibleParty":68,"collaborators":43,"id":71,"slug":72,"hasResults":73,"nctId":74,"briefTitle":75,"officialTitle":76,"acronym":77,"eligibilityCriteria":78,"healthyVolunteers":79,"sex":80,"minAge":81,"maxAge":82,"enrollmentInfo":83,"targetDuration":43,"studyType":86,"phases":87,"briefSummary":89,"conditions":90,"keywords":97,"overallStatus":51,"whyStopped":43,"lastUpdateSubmitDate":104,"lastUpdatePostDateStruct":105,"startDateStruct":108,"completionDateStruct":110,"leadSponsor":112,"locationsCount":113},{"fullName":5,"class":6},"Hasselt University","OTHER",[8,14,18],{"label":9,"type":10,"description":11,"interventionNames":12},"Low-Fatigue Power Training (10% velocity loss)","EXPERIMENTAL","Participants perform a single supervised session of power training on a pneumatic leg press, consisting of 4 sets. During the exercise, movement speed is continuously monitored. In this arm, the exercise set will be stopped when movement speed decreases by 10% compared with the fastest repetition, which corresponds to a low level of fatigue (small amount of repetitions).",[13],"Behavioral: Power Training at Different Fatigue Levels",{"label":15,"type":10,"description":16,"interventionNames":17},"Moderate Fatigue Power Training (30% velocity loss)","Participants perform a single supervised session of power training on a pneumatic leg press, consisting of 4 sets. During the exercise, movement speed is continuously monitored. In this arm, the exercise set will be stopped when movement speed decreases by 30% compared with the fastest repetition, which corresponds to a moderate level of fatigue (more repetitions, performed closer to muscle failure).",[13],{"label":19,"type":10,"description":20,"interventionNames":21},"Cluster-Set Power Training (10% Velocity Loss)","Participants perform a single supervised session of power training on a pneumatic leg press. In this arm, the exercise is organized into 4 cluster sets. A cluster set consists of small groups of repetitions separated by short rest periods within the set. Participants will perform clusters of 3-4 repetitions with 20 seconds of rest between clusters.\n\nDuring the exercise, movement speed is continuously monitored. Each cluster will be performed within the range of 10% velocity loss compared with the fastest repetition, which corresponds to a low level of fatigue. Clusters will continue until the total number of repetitions matches the training volume (amount of total repetitions) reached in the 30% velocity loss condition.\n\nThis design allows participants to complete a similar total training volume as in the moderate fatigue condition, while maintaining lower fatigue, enabling researchers to separate the effects of exercise volume from the effects of fatigue.",[13],[23],{"type":24,"name":25,"description":26,"armGroupLabels":27,"otherNames":28},"BEHAVIORAL","Power Training at Different Fatigue Levels","Participants perform supervised power-training exercises on a pneumatic leg press. The sessions are designed to test different levels of fatigue:\n\n1. In one session, participants stop the exercise set when their movement speed drops by 10%.\n2. In another session, they stop when their movement speed drops by 30%.\n3. In a third session, participants perform the same total work as the 30% session, but stop at 10% velocity loss.\n\nEach session lasts a single training bout (4 sets), and is separated from the next session by one week. During and after each session, researchers measure immediate and post 24h responses to the training in neuromuscular function, physiological responses (e.g., blood markers, muscle oxygenation), functional performance, perceived effort, and muscle soreness.\n\nThis intervention is different from other exercise studies because it focuses on how varying fatigue levels during power training affect immediate performance and recovery in healthy older adults.",[19,9,15],[29,30],"Power Training at Different Velocity Loss Thresholds","Power Training at Different Velocity-Based Training Doses",[32,36],{"name":33,"affiliation":34,"role":35},"Evelien Van Roie, PhD","Hasselt University, Faculty of Rehabilitation Sciences","PRINCIPAL_INVESTIGATOR",{"name":37,"affiliation":34,"role":35},"Bruno Tassignon, PhD",[39,45],{"name":40,"role":41,"phone":42,"phoneExt":43,"email":44},"Max Riesbeck, Master of Science","CONTACT","+32 11 26 84 93",null,"max.riesbeck@uhasselt.be",{"name":33,"role":41,"phone":46,"phoneExt":43,"email":47},"+3211269062","evelien.vanroie@uhasselt.be",[49],{"facility":50,"status":51,"city":52,"state":53,"zip":54,"country":55,"countryCode":56,"cosmosGeoPoint":57,"geoPoint":62,"contacts":63},"REVAL - Faculty of Rehabilitation Sciences","RECRUITING","Diepenbeek","Flanders","3590","Belgium","BE",{"type":58,"coordinates":59},"Point",[60,61],5.41875,50.90769,{"lat":61,"lon":60},[64],{"name":65,"role":41,"phone":66,"phoneExt":43,"email":67},"Faculteit Revalidatiewetenschappen","+32(0)11 26 93 11","reval.rws@uhasselt.be",{"type":35,"investigatorFullName":69,"investigatorTitle":70,"investigatorAffiliation":5,"oldNameTitle":43,"oldOrganization":43},"Evelien Van Roie","Prof. Dr. Evelien Van Roie","100633108","acute-power-training-effects-in-older-adults-100633108",false,"NCT07522398","Acute Power Training Effects in Older Adults","Acute Neuromuscular and Physiological Responses to Different Velocity Loss Thresholds During Power Training in Older Adults","APTE-OA","Inclusion criteria:\n\nParticipants must:\n\n* Be 65 to 85 years old.\n* Be able to live independently and perform everyday activities without help.\n* Not have regularly done resistance or strength training in the past year.\n* Be able to understand study instructions and communicate in the study language.\n* Have a recent statement from their treating physician confirming that their heart and blood vessels are healthy enough to safely take part in this study.\n\nExclusion criteria\n\nParticipants will not be eligible if they have any of the following:\n\n* Unstable heart disease, neurological disease, acute infection, or fever.\n* Use of non-steroidal anti-inflammatory drugs (NSAIDs), such as ibuprofen, in the 5 days before the study.\n* Use of whey protein, casein, or amino acid supplements in the month before the study.\n* Acute or chronic injuries to the legs or lower body muscles.\n* Any injury or condition that prevents safe leg extension exercises.\n* Recent lower-limb joint replacement (less than 6 months ago).\n* Dependence on walking aids.\n* Current participation in another interventional trial.",true,"ALL","65 Years","85 Years",{"count":84,"type":85},42,"ESTIMATED","INTERVENTIONAL",[88],"NA","The goal of this clinical trial is to learn how older adults respond to power training when the level of fatigue during exercise is different. Power training means performing fast movements with moderate loads to improve strength, power and mobility.\n\nThe main questions the study aims to answer are:\n\n* How does the level of fatigue during power training acutely affect strength, movement, and muscle function?\n* How does it affect recovery, muscle soreness, and how hard the exercise feels?\n\nResearchers will compare three power-training sessions with different fatigue levels to see which approach may be safest and most effective for older adults.\n\nParticipants will be healthy older adults aged 65 to 85 years. Each participant will complete three supervised exercise sessions on a leg press machine. The sessions will take place about one week apart.\n\nDuring the study, participants will:\n\n* Perform power training on a pneumatic leg press machine\n* Complete strength and mobility tests before and after exercise\n* Provide small blood samples to measure body responses to exercise\n* Rate how hard the exercise feels\n* Report muscle soreness for up to two days after exercise\n\nThe results may help researchers design safer and more effective power-training programs to improve strength, mobility, and recovery in older adults.",[91,92,93,94,95,96],"Muscle Power","Functional Performance","Older Adults (65 Years and Older)","Neuromuscular Function","Physiological Responses","Healthy Older Adults",[98,99,100,91,101,102,94,92,95,103],"Power Training","Older Adults","Aging","Velocity Loss","Resistance Training","Exercise Fatigue","2026-04-03",{"date":106,"type":107},"2026-04-13","ACTUAL",{"date":109,"type":85},"2026-04-20",{"date":111,"type":85},"2027-01",{"name":5,"class":6},1]