[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100503667":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":20,"centralContacts":24,"locations":32,"responsibleParty":47,"collaborators":19,"id":49,"slug":50,"hasResults":51,"nctId":52,"briefTitle":53,"officialTitle":54,"acronym":55,"eligibilityCriteria":56,"healthyVolunteers":51,"sex":57,"minAge":58,"maxAge":59,"enrollmentInfo":60,"targetDuration":19,"studyType":63,"phases":64,"briefSummary":66,"conditions":67,"keywords":19,"overallStatus":35,"whyStopped":19,"lastUpdateSubmitDate":69,"lastUpdatePostDateStruct":70,"startDateStruct":73,"completionDateStruct":75,"leadSponsor":77,"locationsCount":78},{"fullName":5,"class":6},"University Hospital, Toulouse","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"6 month adapted physical activity","EXPERIMENTAL","The various assessments will be carried out during 2 visits at 6 months interval as part of the usual follow-up at the Toulouse University Hospital. Standard cardiopulmonary exercise test assessment will be coupled with an assessment by an APA coach on the same day.\n\nThe APA program built from the initial assessment will be returned to the child and his family during a videoconference.\n\nIn addition, a regular reassessment and adjustment of this program will be made every 15 days during phone calls by the APA coach.",[13],"Other: Adapted Physical Activity program",[15],{"type":6,"name":16,"description":17,"armGroupLabels":18,"otherNames":19},"Adapted Physical Activity program","The Adaptated Physical Activity program will consist of a Personalized Training Program",[9],null,[21],{"name":22,"affiliation":5,"role":23},"Thomas EDOUARD, MD","PRINCIPAL_INVESTIGATOR",[25,29],{"name":22,"role":26,"phone":27,"phoneExt":19,"email":28},"CONTACT","05 34 54 91 95","edouard.t@chu-toulouse.fr",{"name":30,"role":26,"phone":19,"phoneExt":19,"email":31},"Fernanda BAJANCA","bajanca.f@chu-toulouse.fr",[33],{"facility":34,"status":35,"city":36,"state":19,"zip":19,"country":37,"countryCode":38,"cosmosGeoPoint":39,"geoPoint":44,"contacts":45},"CHU Toulouse","RECRUITING","Toulouse","France","FR",{"type":40,"coordinates":41},"Point",[42,43],1.44367,43.60426,{"lat":43,"lon":42},[46],{"name":22,"role":26,"phone":19,"phoneExt":19,"email":28},{"type":48,"investigatorFullName":19,"investigatorTitle":19,"investigatorAffiliation":19,"oldNameTitle":19,"oldOrganization":19},"SPONSOR","100503667","adapted-physical-activity-program-apa-for-effort-rehabilitation-of-children-and-teenagers-with-marfan-syndrome-100503667",false,"NCT05838235","Adapted Physical Activity Program (APA) for Effort Rehabilitation of Children and Teenagers With Marfan Syndrome","Marfan&Moves (M&M's) : an Adapted Physical Activity Program (APA) for Effort Rehabilitation of Children and Teenagers With Marfan Syndrome: an Interventional, Prospective, Monocentric Study.","M&M's","Inclusion Criteria:\n\n* Genetically confirmed Marfan syndrome or related syndrome\n* Girl or boy aged 7 to 17\n* Informed and written consent signed by at least one of the two holders of parental authority\n* Patient affiliated to a social security scheme or equivalent\n\nExclusion Criteria:\n\n* Cardiac contraindications to the APA program:\n\n  * Severe aortic dilation (aortic diameter \\> 45 mm)\n  * and\u002For left ventricular failure (left ventricular ejection fraction \\\u003C45%)\n  * and\u002For severe mitral leakage ≥ grade 3\n* Pregnancy","ALL","7 Years","17 Years",{"count":61,"type":62},30,"ESTIMATED","INTERVENTIONAL",[65],"NA","This research study aims to evaluate the effect of a 6-month adapted physical activity program (APA) on the endurance capacities (evaluated as the maximum oxygen consumption \\[VO2 peak\\] on a cardiopulmonary exercise test) of children and adolescents with Marfan syndrome or related.",[68],"Marfan Syndrome","2026-03-02",{"date":71,"type":72},"2026-03-03","ACTUAL",{"date":74,"type":72},"2023-04-24",{"date":76,"type":62},"2028-10",{"name":5,"class":6},1]