[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100498660":3},{"organization":4,"armGroups":7,"interventions":32,"overallOfficials":43,"centralContacts":54,"locations":59,"responsibleParty":110,"collaborators":113,"id":117,"slug":118,"hasResults":119,"nctId":120,"briefTitle":121,"officialTitle":121,"acronym":122,"eligibilityCriteria":123,"healthyVolunteers":119,"sex":124,"minAge":125,"maxAge":38,"enrollmentInfo":126,"targetDuration":38,"studyType":129,"phases":130,"briefSummary":132,"conditions":133,"keywords":38,"overallStatus":62,"whyStopped":38,"lastUpdateSubmitDate":135,"lastUpdatePostDateStruct":136,"startDateStruct":139,"completionDateStruct":141,"leadSponsor":143,"locationsCount":144},{"fullName":5,"class":6},"AdventHealth Translational Research Institute","OTHER",[8,14,20,24,28],{"label":9,"type":10,"description":11,"interventionNames":12},"Attention control","SHAM_COMPARATOR","Static stretching",[13],"Behavioral: Progressive stretching",{"label":15,"type":16,"description":17,"interventionNames":18},"75 min\u002Fwk aerobic exercise","EXPERIMENTAL","Aerobic exercise at a dose of 75 minutes per week",[19],"Behavioral: Aerobic exercise",{"label":21,"type":16,"description":22,"interventionNames":23},"150 min\u002Fwk aerobic exercise","Aerobic exercise at a dose of 150 minutes per week",[19],{"label":25,"type":16,"description":26,"interventionNames":27},"225 min\u002Fwk aerobic exercise","Aerobic exercise at a dose of 225 minutes per week",[19],{"label":29,"type":16,"description":30,"interventionNames":31},"300 min\u002Fwk aerobic exercise","Aerobic exercise at a dose of 300 minutes per week",[19],[33,39],{"type":34,"name":35,"description":36,"armGroupLabels":37,"otherNames":38},"BEHAVIORAL","Aerobic exercise","Moderate- to vigorous-intensity aerobic exercise",[21,25,29,15],null,{"type":34,"name":40,"description":41,"armGroupLabels":42,"otherNames":38},"Progressive stretching","Static stretching of eight major muscle groups",[9],[44,48,51],{"name":45,"affiliation":46,"role":47},"Justin C. Brown, Ph.D.","AdventHealth","PRINCIPAL_INVESTIGATOR",{"name":49,"affiliation":50,"role":47},"Jeffrey A. Meyerhardt, M.D., M.P.H.","Dana-Farber Cancer Institute",{"name":52,"affiliation":53,"role":47},"Bette J. Caan, Dr.P.H.","Kaiser Permanente",[55],{"name":45,"role":56,"phone":57,"phoneExt":38,"email":58},"CONTACT","4076095000","Justin.Brown4@AdventHealth.com",[60,80,95],{"facility":61,"status":62,"city":63,"state":64,"zip":65,"country":66,"countryCode":67,"cosmosGeoPoint":68,"geoPoint":73,"contacts":74},"Kaiser Permanente Northern California","RECRUITING","Oakland","California","94612","United States","US",{"type":69,"coordinates":70},"Point",[71,72],-122.2708,37.80437,{"lat":72,"lon":71},[75,78],{"name":76,"role":56,"phone":38,"phoneExt":38,"email":77},"Michelle Ross","Michelle.C.Ross@kp.org",{"name":79,"role":47,"phone":38,"phoneExt":38,"email":38},"Bette J Caan, Dr.P.H.",{"facility":46,"status":62,"city":81,"state":82,"zip":83,"country":66,"countryCode":67,"cosmosGeoPoint":84,"geoPoint":88,"contacts":89},"Orlando","Florida","32804",{"type":69,"coordinates":85},[86,87],-81.37924,28.53834,{"lat":87,"lon":86},[90,93],{"name":91,"role":56,"phone":38,"phoneExt":38,"email":92},"Abigail Tice, Ph.D.","Abigail.Tice@AdventHealth.com",{"name":94,"role":47,"phone":38,"phoneExt":38,"email":38},"Justin Brown, Ph.D.",{"facility":50,"status":62,"city":96,"state":97,"zip":98,"country":66,"countryCode":67,"cosmosGeoPoint":99,"geoPoint":103,"contacts":104},"Boston","Massachusetts","02215",{"type":69,"coordinates":100},[101,102],-71.05977,42.35843,{"lat":102,"lon":101},[105,108],{"name":106,"role":56,"phone":38,"phoneExt":38,"email":107},"Christine Lu, M.P.H.","christine_lu@dfci.harvard.edu",{"name":109,"role":47,"phone":38,"phoneExt":38,"email":38},"Jeffrey A Meyerhardt, M.D.",{"type":47,"investigatorFullName":111,"investigatorTitle":112,"investigatorAffiliation":5,"oldNameTitle":38,"oldOrganization":38},"Justin Brown","Senior Investigator",[114],{"name":115,"class":116},"National Cancer Institute (NCI)","NIH","100498660","adaptive-randomization-of-aerobic-exercise-during-chemotherapy-in-colon-cancer-100498660",false,"NCT05773144","Adaptive Randomization of Aerobic Exercise During Chemotherapy in Colon Cancer","ACTION","Inclusion Criteria:\n\n* Age ≥18 years\n* Histologically confirmed stage II or III colon cancer\n* Completed surgical resection with curative intent\n* Plan to initiate chemotherapy\n* Engage in \\\u003C60 minutes per week of moderate- to vigorous-intensity structured aerobic exercise\n* No planned major surgery during the study period\n* Readiness to exercise, as determined by a modified version of the Physical Activity Readiness Questionnaire\n* Can walk 400 meters\n* Can read and speak English\n* Ability to provide written informed consent\n* Provide written approval by qualified healthcare professional\n* Willing to be randomized\n\nExclusion Criteria:\n\n* Evidence of metastatic colon cancer\n* Concurrently actively treated other (non-colon) cancer\n* Currently pregnant, breastfeeding, or planning to become pregnant within the next 24 weeks\n* Currently participating in another study with competing outcomes\n* Any other condition that, in the opinion of the investigator, would preclude participation or successful compliance with the protocol\n* Any other situation that, in the opinion of the investigator, would negatively impact subject safety or successful compliance with the protocol","ALL","18 Years",{"count":127,"type":128},219,"ESTIMATED","INTERVENTIONAL",[131],"NA","To goal of this clinical trial is to quantify the dose-response effects of aerobic exercise training compared to attention control on chemotherapy relative dose intensity in colon cancer survivors.",[134],"Colonic Neoplasms","2026-01-05",{"date":137,"type":138},"2026-01-07","ACTUAL",{"date":140,"type":138},"2023-06-01",{"date":142,"type":128},"2027-05-01",{"name":5,"class":6},3]