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Popescu, MD","STUDY_CHAIR",[40,46],{"name":41,"role":42,"phone":43,"phoneExt":44,"email":45},"Roland Tilz, Prof. Dr.","CONTACT","+49451500","44672","roland.tilz@uksh.de",{"name":47,"role":42,"phone":43,"phoneExt":44,"email":48},"Charlotte Eitel, Prof. Dr.","charlotte.eitel@uksh.de",[50,70,82],{"facility":51,"status":52,"city":53,"state":54,"zip":55,"country":56,"countryCode":57,"cosmosGeoPoint":58,"geoPoint":63,"contacts":64},"University Hospital Eppendorf, Hamburg, Germany","RECRUITING","Hamburg","Free and Hanseatic City of Hamburg","20251","Germany","DE",{"type":59,"coordinates":60},"Point",[61,62],9.99302,53.55073,{"lat":62,"lon":61},[65],{"name":66,"role":42,"phone":67,"phoneExt":68,"email":69},"Andreas Metzner, Prof. Dr.","0049407410","58320","a.metzner@uke.de",{"facility":71,"status":52,"city":53,"state":54,"zip":72,"country":56,"countryCode":57,"cosmosGeoPoint":73,"geoPoint":75,"contacts":76},"Asklepios Klinik Altona","22763",{"type":59,"coordinates":74},[61,62],{"lat":62,"lon":61},[77],{"name":78,"role":42,"phone":79,"phoneExt":80,"email":81},"Christian H. Heeger, Prof. Dr.","004940181881","1221","c.heeger@asklepios.com",{"facility":83,"status":52,"city":84,"state":85,"zip":86,"country":56,"countryCode":57,"cosmosGeoPoint":87,"geoPoint":91,"contacts":92},"Clinic for Rhythmologiy Luebeck, Schleswig-Holstein Germany","Lübeck","Schleswig-Holstein","23538",{"type":59,"coordinates":88},[89,90],10.68729,53.86893,{"lat":90,"lon":89},[93,96],{"name":41,"role":42,"phone":94,"phoneExt":95,"email":45},"0049451500","44511",{"name":47,"role":42,"phone":94,"phoneExt":95,"email":48},{"type":98,"investigatorFullName":99,"investigatorTitle":100,"investigatorAffiliation":5,"oldNameTitle":101,"oldOrganization":101},"PRINCIPAL_INVESTIGATOR","Roland Richard Tilz, MD","Head of Electrophysiology Department",null,[103],{"name":104,"class":6},"IHF GmbH - Institut für Herzinfarktforschung","100380959","additional-left-atrial-appendage-isolation-during-balloon-ablation-for-persistent-or-long-standing-persistent-atrial-fibrillation-100380959",false,"NCT04240366","Additional Left Atrial Appendage Isolation During Balloon Ablation for Persistent or Long-standing Persistent Atrial Fibrillation","LALA-LAND-AF","Inclusion Criteria:\n\n1. Persistent or long-standing persistent AF (i.e. continuous AF that was\u002Fis sustained \\>7 days or \\>12 months, respectively)\n2. Age ≥18 and ≤80 years\n3. Indication for AF ablation as per current guidelines\n\nExclusion Criteria:\n\n1. Missing informed consent\n2. LAA diameter \\>25mm 10mm distant from circumflex artery assessed by TEE\n3. Paroxysmal atrial fibrillation\n4. Long-standing persistent atrial fibrillation with a continuous AF duration of \\>4 years\n5. Previous pulmonary vein isolation or MAZE surgery\n6. Previous led atrial appendage closure or surgical excision\n7. Left atrial diameter \\>60 mm at baseline\n8. Left atrial thrombus at baseline","ALL","18 Years",{"count":115,"type":116},350,"ESTIMATED","INTERVENTIONAL",[119],"NA","Additional left atrial appendage isolation during balloon ablation for persistent or long-standing persistent atrial fibrillation can reduce atrial fibrillation reoccurrence within 3-12 months compared to balloon-based pulmonary vein isolation only.",[122],"Persistent or Long-standing Persistent Atrial Fibrillation","2024-08-28",{"date":125,"type":126},"2024-08-29","ACTUAL",{"date":128,"type":126},"2019-12-17",{"date":130,"type":116},"2028-08",{"name":5,"class":6},3]