[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100600152":3},{"organization":4,"armGroups":7,"interventions":8,"overallOfficials":7,"centralContacts":7,"locations":7,"responsibleParty":12,"collaborators":7,"id":16,"slug":17,"hasResults":18,"nctId":19,"briefTitle":20,"officialTitle":21,"acronym":7,"eligibilityCriteria":22,"healthyVolunteers":18,"sex":23,"minAge":24,"maxAge":7,"enrollmentInfo":25,"targetDuration":7,"studyType":28,"phases":7,"briefSummary":29,"conditions":30,"keywords":7,"overallStatus":33,"whyStopped":7,"lastUpdateSubmitDate":34,"lastUpdatePostDateStruct":35,"startDateStruct":38,"completionDateStruct":40,"leadSponsor":42,"locationsCount":7},{"fullName":5,"class":6},"Gangnam Severance Hospital","OTHER",null,[9],{"type":6,"name":10,"description":11,"armGroupLabels":7,"otherNames":7},"Tumor grade (I or II vs. III)","We compared the prognosis according to the tumor grade stratified by 21-gene recurrence score",{"type":13,"investigatorFullName":14,"investigatorTitle":15,"investigatorAffiliation":5,"oldNameTitle":7,"oldOrganization":7},"PRINCIPAL_INVESTIGATOR","Sung Gwe Ahn","Professor","100600152","additional-prognostic-value-of-tumor-grade-beyond-the-21-gene-recurrence-score-100600152",false,"NCT07093775","Additional Prognostic Value of Tumor Grade Beyond the 21-gene Recurrence Score","Prognostic Implication of Tumor Grade in Patients With Node-negative Breast Cancer Aged ≤ 50 Years With 21-gene Recurrence Scores of 11-25","Inclusion Criteria:\n\n* Patients with hormone receptor-positive, HER2-negative early-stage breast cancer\n* Patients treated between January 2011 and December 2023\n* Patients with available clinicopathologic data and 21-gene Oncotype DX assay results confirmed through electronic medical records\n\nExclusion Criteria:\n\n* Patients with breast cancer under the age of 20\n* Patients diagnosed with stage IV breast cancer\n* Patients for whom clinicopathologic data cannot be retrieved from electronic medical records","ALL","20 Years",{"count":26,"type":27},4000,"ESTIMATED","OBSERVATIONAL","To evaluated the prognostic significance of tumor grade in patients with node-negative, hormone receptor-positive, and human epidermal growth factor receptor 2-negative breast cancers treated according to RS-guided strategies.",[31,32],"Breast Cancer","Tumor Grade","NOT_YET_RECRUITING","2025-07-22",{"date":36,"type":37},"2025-07-30","ACTUAL",{"date":39,"type":27},"2025-07",{"date":41,"type":27},"2026-03",{"name":5,"class":6}]