[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100599928":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":29,"centralContacts":34,"locations":40,"responsibleParty":71,"collaborators":74,"id":77,"slug":78,"hasResults":79,"nctId":80,"briefTitle":81,"officialTitle":82,"acronym":25,"eligibilityCriteria":83,"healthyVolunteers":79,"sex":84,"minAge":85,"maxAge":25,"enrollmentInfo":86,"targetDuration":25,"studyType":89,"phases":90,"briefSummary":92,"conditions":93,"keywords":95,"overallStatus":99,"whyStopped":25,"lastUpdateSubmitDate":100,"lastUpdatePostDateStruct":101,"startDateStruct":104,"completionDateStruct":106,"leadSponsor":108,"locationsCount":109},{"fullName":5,"class":6},"Harvard Medical School (HMS and HSDM)","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Additive manufacturing","EXPERIMENTAL","additively manufactured implant-supported prostheses",[13],"Device: AM manufacturing method",{"label":15,"type":16,"description":17,"interventionNames":18},"Subtractive manufacturing","ACTIVE_COMPARATOR","subtractively manufactured implant-supported prostheses",[19],"Device: SM manufacturing method",[21,26],{"type":22,"name":23,"description":11,"armGroupLabels":24,"otherNames":25},"DEVICE","AM manufacturing method",[9],null,{"type":22,"name":27,"description":17,"armGroupLabels":28,"otherNames":25},"SM manufacturing method",[15],[30],{"name":31,"affiliation":32,"role":33},"German O Gallucci, Professor","Harvard School of Dental Medicine","PRINCIPAL_INVESTIGATOR",[35],{"name":36,"role":37,"phone":38,"phoneExt":25,"email":39},"Kevser Pala, Dr.med.dent","CONTACT","+41764084037","kevser.pala@zzm.uzh.ch",[41,57],{"facility":32,"status":25,"city":42,"state":43,"zip":44,"country":45,"countryCode":46,"cosmosGeoPoint":47,"geoPoint":52,"contacts":53},"Boston","Massachusetts","02115","United States","US",{"type":48,"coordinates":49},"Point",[50,51],-71.05977,42.35843,{"lat":51,"lon":50},[54],{"name":31,"role":37,"phone":55,"phoneExt":25,"email":56},"617-432-5764","german_gallucci@hsdm.harvard.edu",{"facility":58,"status":25,"city":59,"state":60,"zip":61,"country":62,"countryCode":63,"cosmosGeoPoint":64,"geoPoint":68,"contacts":69},"Center of Dental Medicine, University of Zurich","Zurich","Canton of Zurich","8032","Switzerland","CH",{"type":48,"coordinates":65},[66,67],8.55,47.36667,{"lat":67,"lon":66},[70],{"name":36,"role":37,"phone":38,"phoneExt":25,"email":39},{"type":33,"investigatorFullName":72,"investigatorTitle":73,"investigatorAffiliation":5,"oldNameTitle":25,"oldOrganization":25},"German O. Gallucci","Professor",[75],{"name":76,"class":6},"University of Zurich","100599928","additively-versus-subtractively-manufactured-implant-supported-fixed-dental-prostheses-100599928",false,"NCT07090863","Additively Versus Subtractively Manufactured Implant Supported Fixed Dental Prostheses","Additively (AM) Versus Subtractively (SM) Manufactured Implant Supported Fixed Dental Prostheses (iFDPs)","Inclusion Criteria:\n\n* Signed Informed Consent Form in English language\n* ≥ 20 years of age\n* In need of at least one definitive screw retained premolar or molar iFDP on an existing dental implant (Straumann AG)\n* Presence of at least one adjacent tooth at the implant site\n* Adequate oral hygiene\n* Capability to comply with the study procedures\n\nExclusion Criteria:\n\n* Pregnant or lactating women\n* Known or suspected non-compliance, drug or alcohol abuse\n* Severe periodontal and peri-implant disease","ALL","20 Years",{"count":87,"type":88},50,"ESTIMATED","INTERVENTIONAL",[91],"NA","This research is being done to evaluate the clinical, technical, biological, and aesthetic results of two different fabrication methods (additive and subtractive) for creating implant-supported fixed dental prostheses (iFDPs). Patients will receive an iFDP, meaning an implant-supported crown, according to regular treatment protocols. The fabrication method used to create the implant-supported crown will be decided in a randomised way. Clinical and radiological examinations will be performed prior to and when receiving the implant-supported crown and during a follow-up period of 3 years. Furthermore, technician- and patient-reported outcomes will be evaluated used questionnaires.",[94],"Dental Prosthesis, Implant-Supported",[96,97,98],"3D-printing","implant-supported prostheses","additive manufacturing","NOT_YET_RECRUITING","2025-07-31",{"date":102,"type":103},"2025-08-05","ACTUAL",{"date":105,"type":88},"2025-07-30",{"date":107,"type":88},"2029-07-20",{"name":5,"class":6},2]