[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100336664":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":28,"centralContacts":32,"locations":38,"responsibleParty":73,"collaborators":76,"id":80,"slug":81,"hasResults":82,"nctId":83,"briefTitle":84,"officialTitle":84,"acronym":24,"eligibilityCriteria":85,"healthyVolunteers":82,"sex":86,"minAge":87,"maxAge":88,"enrollmentInfo":89,"targetDuration":24,"studyType":92,"phases":93,"briefSummary":95,"conditions":96,"keywords":98,"overallStatus":40,"whyStopped":24,"lastUpdateSubmitDate":100,"lastUpdatePostDateStruct":101,"startDateStruct":104,"completionDateStruct":106,"leadSponsor":108,"locationsCount":109},{"fullName":5,"class":6},"University of Kentucky","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"SMART Intervention","EXPERIMENTAL","The SMART intervention will utilize the elements of the Standard of Care intervention, and will also include \"Sensorimotor Improvements\" and other specific additions that will focus on sensory inputs, motor outputs, and integration of the sensory and motor pathways.",[13],"Other: SMART Intervention",{"label":15,"type":16,"description":17,"interventionNames":18},"Standard of Care Intervention","ACTIVE_COMPARATOR","The Standard of Care intervention will include restoration of ankle joint range of motion, strength and functional movement.",[19],"Other: Standard of Care Intervention",[21,25],{"type":6,"name":9,"description":22,"armGroupLabels":23,"otherNames":24},"Ankle rehabilitation with the addition of sensorimotor components",[9],null,{"type":6,"name":15,"description":26,"armGroupLabels":27,"otherNames":24},"Ankle rehabilitation focused on restoring range of motion, strength and balance",[15],[29],{"name":30,"affiliation":5,"role":31},"Phillip Gribble, PhD","PRINCIPAL_INVESTIGATOR",[33],{"name":34,"role":35,"phone":36,"phoneExt":24,"email":37},"Kyle Kosik, PhD","CONTACT","859-323-9850","kyle.kosik@uky.edu",[39,58],{"facility":5,"status":40,"city":41,"state":42,"zip":43,"country":44,"countryCode":45,"cosmosGeoPoint":46,"geoPoint":51,"contacts":52},"RECRUITING","Lexington","Kentucky","40506","United States","US",{"type":47,"coordinates":48},"Point",[49,50],-84.47772,37.98869,{"lat":50,"lon":49},[53,57],{"name":54,"role":35,"phone":55,"phoneExt":24,"email":56},"Phillip Gribble","859-218-0885","phillip.gribble@uky.edu",{"name":30,"role":31,"phone":24,"phoneExt":24,"email":24},{"facility":59,"status":40,"city":60,"state":61,"zip":62,"country":44,"countryCode":45,"cosmosGeoPoint":63,"geoPoint":67,"contacts":68},"University of North Carolina at Chapel Hill","Chapel Hill","North Carolina","27599",{"type":47,"coordinates":64},[65,66],-79.05584,35.9132,{"lat":66,"lon":65},[69],{"name":70,"role":35,"phone":71,"phoneExt":24,"email":72},"Erik Wikstrom, PhD","919-962-2260","wikstrom@unc.edu",{"type":74,"investigatorFullName":54,"investigatorTitle":75,"investigatorAffiliation":5,"oldNameTitle":24,"oldOrganization":24},"SPONSOR_INVESTIGATOR","Professor",[77],{"name":78,"class":79},"United States Department of Defense","FED","100336664","addressing-neuromuscular-deficits-for-improved-outcomes-in-ankle-rehabilitation-100336664",false,"NCT03663361","Addressing Neuromuscular Deficits for Improved Outcomes in Ankle Rehabilitation","Inclusion Criteria:\n\n* initiating rehabilitation for a first time acute grade I, II, or III LAS\n* have sustained within 72 hours of study enrollment\n* diagnosed by a physician, medic, athletic trainer, physical therapist, or other providing medical coverage in operational environments as having sustained a LAS\n\nExclusion Criteria:\n\n* personal or familial history of epilepsy or seizures\n* history of migraine headaches\n* ocular foreign body, increased intracranial pressure, open head injury or significant closed head injury\n* cochlear implants\n* implanted brain stimulators, aneurysm clips or other metal in the head (except mouth)\n* implanted medication pumps, pacemakers or intracardiac lines\n* current medication with tricyclic anti-depressants, neuroleptic agents or other drugs that lower seizure threshold\n* history of diagnosed major psychiatric disorder\n* history of illicit drug use\n* current alcohol abuse or currently withdrawing from alcohol abuse\n* history of heart disease","ALL","18 Years","44 Years",{"count":90,"type":91},150,"ESTIMATED","INTERVENTIONAL",[94],"NA","The purpose of this project is to compare a novel sensorimotor ankle rehabilitation training (SMART) protocol for Lateral ankle sprains (LASs) against a standard of care (SOC) protocol to determine if it is more successful at producing successful one-year outcomes and lower rates of re-injury and improved health. This will address the identified needs for evidence-support and reintegration strategies to improve understanding of the management of patient rehabilitation strategies throughout the rehabilitation process following neuromusculoskeletal injury. The project will validate an innovative rehabilitation approach while providing metrics of success using a variety of clinical and innovative markers.",[97],"Ankle Sprains",[99],"ankle sprain, sensorimotor, rehabilitation, osteoarthritis","2026-02-18",{"date":102,"type":103},"2026-02-20","ACTUAL",{"date":105,"type":103},"2019-11-12",{"date":107,"type":91},"2026-07",{"name":54,"class":6},2]