[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100590925":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":26,"centralContacts":30,"locations":36,"responsibleParty":57,"collaborators":26,"id":60,"slug":61,"hasResults":62,"nctId":63,"briefTitle":64,"officialTitle":65,"acronym":26,"eligibilityCriteria":66,"healthyVolunteers":62,"sex":67,"minAge":68,"maxAge":69,"enrollmentInfo":70,"targetDuration":26,"studyType":73,"phases":74,"briefSummary":76,"conditions":77,"keywords":79,"overallStatus":39,"whyStopped":26,"lastUpdateSubmitDate":83,"lastUpdatePostDateStruct":84,"startDateStruct":87,"completionDateStruct":89,"leadSponsor":91,"locationsCount":92},{"fullName":5,"class":6},"Chinese University of Hong Kong","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Bright light therapy group","EXPERIMENTAL","Blue-enriched white light",[13],"Device: Bright light therapy",{"label":15,"type":16,"description":17,"interventionNames":18},"Dim red light group","PLACEBO_COMPARATOR","Dim red light",[19],"Device: Dim red light",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"DEVICE","Bright light therapy","Exposure to blue-enriched white light for 15-30 minutes a day for 8 weeks",[9],null,{"type":22,"name":17,"description":28,"armGroupLabels":29,"otherNames":26},"Exposure to dim red light for 15-30 minutes a day for 8 weeks.",[15],[31],{"name":32,"role":33,"phone":34,"phoneExt":26,"email":35},"Joey WY Chan","CONTACT","+852 39197647","joeywychan@cuhk.edu.hk",[37],{"facility":38,"status":39,"city":40,"state":40,"zip":41,"country":40,"countryCode":42,"cosmosGeoPoint":43,"geoPoint":48,"contacts":49},"The Chinese University of Hong Kong","RECRUITING","Hong Kong","999077","HK",{"type":44,"coordinates":45},"Point",[46,47],114.17469,22.27832,{"lat":47,"lon":46},[50,53],{"name":51,"role":33,"phone":52,"phoneExt":26,"email":35},"Joey WY Chan, FHKAM(Psych)","+862 39197647",{"name":54,"role":33,"phone":55,"phoneExt":26,"email":56},"Xingle Gao","+852 92916602","xinglegao@link.cuhk.edu.hk",{"type":58,"investigatorFullName":32,"investigatorTitle":59,"investigatorAffiliation":5,"oldNameTitle":26,"oldOrganization":26},"PRINCIPAL_INVESTIGATOR","Clinical Associate Professor","100590925","adjunctive-bright-light-therapy-in-adolescents-with-depression-and-eveningness-100590925",false,"NCT06973759","Adjunctive Bright Light Therapy in Adolescents With Depression and Eveningness","Bright Light Therapy for Adolescents With Depression and Eveningness - a Randomized, Placebo-controlled, Assessor-blinded Study","Inclusion Criteria:\n\n1. Chinese, aged 12-19 years old;\n2. Written informed assent\u002Fconsent of participation into the study is given by the participant and his\u002Fher parent or guardian (for those aged under 18), respectively;\n3. Having a DSM-5 diagnosis of unipolar non-seasonal depression as confirmed by the Chinese version of the Kiddie-Schedule for Affective Disorders and Schizophrenia (K-SADS) psychiatric interview, DSM-5 Seasonal specifier, AND having a score on Children's Depression Rating Scale (CDRS-R) at least 40;\n4. Being classified as evening chronotype according to the score on the reduced Horne-Östberg Morning-Eveningness Questionnaire (rMEQ), i.e. \\\u003C12.\n\nExclusion Criteria:\n\n1. A current diagnosis of substance abuse or dependence; a current or past history of manic or hypomanic episode, schizophrenia spectrum disorders, organic mental disorders, or intellectual disabilities;\n2. Having a clinically significant suicidality (presence of suicidal ideation with a plan or an attempt) as assessed by K-SADS;\n3. Having been enrolled in any other clinical trial investigational products within one month at the entry of the study;\n4. Initiation of or change in antidepressant medication within past 4 weeks;\n5. Having been or is currently receiving any structured psychotherapy;\n6. With hearing or speech deficit;\n7. Night shift worker;\n8. Trans-meridian flight across at least two time zones in the past 3 months and during the study;\n9. Presence of an eye disease, e.g., retinal blindness, severe cataract, glaucoma.","ALL","12 Years","19 Years",{"count":71,"type":72},90,"ESTIMATED","INTERVENTIONAL",[75],"NA","This study examines the efficacy of bright light therapy as a treatment for adolescents diagnosed with unipolar non-seasonal depression who exhibit an evening chronotype.",[78],"Depression, Unipolar",[80,81,23,82],"Depression","Eveningness","Adolescents","2026-03-18",{"date":85,"type":86},"2026-03-19","ACTUAL",{"date":88,"type":86},"2025-11-01",{"date":90,"type":72},"2028-06-30",{"name":5,"class":6},1]