[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100340930":3},{"organization":4,"armGroups":7,"interventions":7,"overallOfficials":8,"centralContacts":16,"locations":22,"responsibleParty":41,"collaborators":44,"id":52,"slug":53,"hasResults":54,"nctId":55,"briefTitle":56,"officialTitle":57,"acronym":7,"eligibilityCriteria":58,"healthyVolunteers":54,"sex":59,"minAge":60,"maxAge":7,"enrollmentInfo":61,"targetDuration":7,"studyType":64,"phases":7,"briefSummary":65,"conditions":66,"keywords":70,"overallStatus":25,"whyStopped":7,"lastUpdateSubmitDate":75,"lastUpdatePostDateStruct":76,"startDateStruct":79,"completionDateStruct":81,"leadSponsor":83,"locationsCount":84},{"fullName":5,"class":6},"Icahn School of Medicine at Mount Sinai","OTHER",null,[9,12,14],{"name":10,"affiliation":5,"role":11},"Silvia De Rubeis, Ph.D.","PRINCIPAL_INVESTIGATOR",{"name":13,"affiliation":5,"role":11},"Paige Siper, Ph.D.",{"name":15,"affiliation":5,"role":11},"Alexander Kolevzon, MD",[17],{"name":18,"role":19,"phone":20,"phoneExt":7,"email":21},"Tess Levy","CONTACT","212-241-5290","tess.levy@mssm.edu",[23],{"facility":24,"status":25,"city":26,"state":26,"zip":27,"country":28,"countryCode":29,"cosmosGeoPoint":30,"geoPoint":35,"contacts":36},"The Seaver Autism Center for Research and Treatment","RECRUITING","New York","10029","United States","US",{"type":31,"coordinates":32},"Point",[33,34],-74.00597,40.71427,{"lat":34,"lon":33},[37],{"name":38,"role":19,"phone":39,"phoneExt":7,"email":40},"Samantha Bright, BA","212-241-0961","samantha.bright@mssm.edu",{"type":11,"investigatorFullName":42,"investigatorTitle":43,"investigatorAffiliation":5,"oldNameTitle":7,"oldOrganization":7},"Alexander Kolevzon","Clinical Director of the Seaver Autism Center for Research and Treatment, Professor of Psychiatry and Pediatrics and Director of Child and Adolescent Psychiatry",[45,48,50],{"name":46,"class":47},"The Seaver Foundation","UNKNOWN",{"name":49,"class":6},"Autism Science Foundation",{"name":51,"class":6},"Research Foundation for Mental Hygiene, Inc.","100340930","adnp-syndrome-the-seaver-autism-center-for-research-and-treatment-is-characterizing-adnp-related-neurodevelopmental-disorders-using-genetic-medical-and-neuropsychological-measures-100340930",false,"NCT03718936","ADNP Syndrome: The Seaver Autism Center for Research and Treatment is Characterizing ADNP-related Neurodevelopmental Disorders Using Genetic, Medical, and Neuropsychological Measures.","The Seaver Autism Center for Research and Treatment - Assessment Core","Inclusion Criteria:\n\n* Eligible participants must have a documented variant affecting the ADNP gene that the research team determines to be likely or definitely pathogenic.\n* Eligible participants must be at least 2 years of age.\n\nExclusion Criteria:\n\n* none","ALL","2 Years",{"count":62,"type":63},30,"ESTIMATED","OBSERVATIONAL","ADNP, also known as Activity Dependent Neuroprotective Protein, is a rare neurodevelopmental disorder caused by mutations encompassing the ADNP gene on chromosome 20. Clinically, ADNP syndrome is characterized by intellectual disability and global developmental delay. This study seeks to characterize ADNP-related neurodevelopmental disorders using a number of genetic, medical and neuropsychological measures.",[67,68,69],"ADNP","Helsmoortel-Van Der Aa Syndrome","Autism Spectrum Disorder",[67,71,69,72,73,74],"Intellectual Disability","Global Developmental Delay","Neurodevelopmental Deficits","Developmental Disability","2025-05-06",{"date":77,"type":78},"2025-05-09","ACTUAL",{"date":80,"type":78},"2017-11-14",{"date":82,"type":63},"2027-03",{"name":5,"class":6},1]