[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100606404":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":26,"centralContacts":31,"locations":37,"responsibleParty":54,"collaborators":58,"id":61,"slug":26,"hasResults":62,"nctId":63,"briefTitle":64,"officialTitle":65,"acronym":26,"eligibilityCriteria":66,"healthyVolunteers":62,"sex":67,"minAge":68,"maxAge":69,"enrollmentInfo":70,"targetDuration":26,"studyType":73,"phases":74,"briefSummary":76,"conditions":77,"keywords":26,"overallStatus":40,"whyStopped":26,"lastUpdateSubmitDate":82,"lastUpdatePostDateStruct":83,"startDateStruct":86,"completionDateStruct":88,"leadSponsor":90,"locationsCount":91},{"fullName":5,"class":6},"University of Seville","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Experimental - Chlorhexidine gluconate-impregnated dressing","EXPERIMENTAL","Participants receive advanced transparent dressings impregnated with chlorhexidine gluconate at the CVC insertion site.",[13],"Device: 3M™ Tegaderm™ Antimicrobial Transparent Dressing (chlorhexidine gluconate-impregnated)",{"label":15,"type":16,"description":17,"interventionNames":18},"Control - Conventional transparent dressing","ACTIVE_COMPARATOR","Participants receive standard transparent polyurethane dressing without antimicrobial activity at the CVC insertion site.",[19],"Device: Conventional transparent polyurethane dressing",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"DEVICE","3M™ Tegaderm™ Antimicrobial Transparent Dressing (chlorhexidine gluconate-impregnated)","Individually applied transparent dressing containing chlorhexidine gluconate (0.5-1 mg\u002Fcm²) for antimicrobial protection at the central venous catheter insertion site. The dressing maintains site visibility, reduces catheter manipulation frequency, and provides sustained release of chlorhexidine to lower colonisation and bloodstream infection risk.",[9],null,{"type":22,"name":28,"description":29,"armGroupLabels":30,"otherNames":26},"Conventional transparent polyurethane dressing","Transparent polyurethane dressing without antimicrobial impregnation, applied at the central venous catheter insertion site. This dressing allows site inspection and is widely used in standard paediatric intensive care protocols but provides no antimicrobial activity.",[15],[32],{"name":33,"role":34,"phone":35,"phoneExt":26,"email":36},"Manuel Pabón-Carrasco","CONTACT","+34 669709548","mpabon2@us.es",[38],{"facility":39,"status":40,"city":41,"state":42,"zip":43,"country":44,"countryCode":45,"cosmosGeoPoint":46,"geoPoint":51,"contacts":52},"Hospital Universitario Virgen del Rocío - Hospital Infantil","RECRUITING","Seville","Sevilla","41004","Spain","ES",{"type":47,"coordinates":48},"Point",[49,50],-5.97317,37.38283,{"lat":50,"lon":49},[53],{"name":33,"role":34,"phone":26,"phoneExt":26,"email":36},{"type":55,"investigatorFullName":56,"investigatorTitle":57,"investigatorAffiliation":5,"oldNameTitle":26,"oldOrganization":26},"PRINCIPAL_INVESTIGATOR","MANUEL PABON CARRASCO","Principal Investigator, Faculty of Nursing, Physiotherapy and Podiatry, University of Seville",[59],{"name":60,"class":6},"Hospitales Universitarios Virgen del Rocío","100606404",false,"NCT07175116","Advanced Dressings for CVC Infection Prevention in PICU","Use of Advanced Fixation Dressings in Reducing Central Venous Catheter-related Bloodstream Infections in a Paediatric Intensive Care Unit","Inclusion Criteria:\n\n* Admission to paediatric intensive care unit (PICU)\n* Central venous catheter placement (central or peripherally inserted)\n* Informed consent obtained from parent\u002Flegal guardian\n\nExclusion Criteria:\n\n* Known immunological disorders\n* Neutropenia (\\\u003C500\u002Fmm³)\n* Pre-existing colonisation or infection with multidrug-resistant organisms","ALL","2 Months","18 Years",{"count":71,"type":72},250,"ESTIMATED","INTERVENTIONAL",[75],"NA","Randomised, single-blind clinical trial comparing chlorhexidine gluconate-impregnated transparent dressings versus conventional transparent dressings in the prevention of central venous catheter-related bloodstream infections (CVC-BSI) in paediatric patients admitted to a tertiary hospital PICU. Outcomes include incidence of BRCVC, catheter colonisation, dressing-related skin complications, and number of dressing changes.",[78,79,80,81],"Catheter-Related Infections","Central Venous Catheters","Bloodstream Infection","Pediatric Intensive Care Units","2025-09-11",{"date":84,"type":85},"2025-09-16","ACTUAL",{"date":87,"type":85},"2024-05-01",{"date":89,"type":72},"2025-11-15",{"name":5,"class":6},1]