[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100371494":3},{"organization":4,"armGroups":7,"interventions":26,"overallOfficials":32,"centralContacts":37,"locations":47,"responsibleParty":66,"collaborators":10,"id":69,"slug":70,"hasResults":71,"nctId":72,"briefTitle":73,"officialTitle":73,"acronym":74,"eligibilityCriteria":75,"healthyVolunteers":71,"sex":76,"minAge":77,"maxAge":10,"enrollmentInfo":78,"targetDuration":81,"studyType":82,"phases":10,"briefSummary":83,"conditions":84,"keywords":10,"overallStatus":49,"whyStopped":10,"lastUpdateSubmitDate":88,"lastUpdatePostDateStruct":89,"startDateStruct":92,"completionDateStruct":94,"leadSponsor":96,"locationsCount":97},{"fullName":5,"class":6},"Centre hospitalier de l'Université de Montréal (CHUM)","OTHER",[8,14,18,22],{"label":9,"type":10,"description":11,"interventionNames":12},"Endoscopic mucosal resection (EMR)",null,"It has become the standard treatment for superficial tumors of the gastrointestinal tract, either flat or sessile: precancerous lesions and superficial cancers with no or low ganglionic risk. The pre-injection of physiological serum detaches the lesion from the deep plane and allows, with great security, the resection of the mucosa, muscularis mucosae with part of the submucosa, whatever the size and location of the lesion. Compared to other techniques, it allows a histological analysis which dictates the subsequent conduct and the possible need for a complementary surgery.",[13],"Procedure: Polypectomy or myotomy",{"label":15,"type":10,"description":16,"interventionNames":17},"Endoscopic mucosal dissection (ESD)","This technique uses submucosal injection and special knives to make a peri-lesional circumferential incision, followed by dissection through the submucosal sub-lesion.",[13],{"label":19,"type":10,"description":20,"interventionNames":21},"Radio Frequency Ablation (RFA) and Argon Plasma Ablation (APC)","This is a mucosal thermo-destruction technique. It uses a generator that delivers a sinusoidal current of high frequency to a probe covered with bipolar electrodes in tight network ensuring a uniform diffusion of the thermal effect. The tissue penetration is superficial on 1mm, intended to eradicate the epithelium up to the muscularis mucosae. Circumferential or focal probes are used as a function of the length of the segment to be treated.",[13],{"label":23,"type":10,"description":24,"interventionNames":25},"Per Oral Endoscopic Myotomy (POEM)","This technique allows a myotomy on the 8 cm of the lower esophagus extended on the gastric side of the cardia, totally endoscopically, after having approached and tunneled the esophageal submucosa.\n\nLess invasive, it gradually replaces the pneumatic dilatation and surgical myotomy of Heller.\n\nIt requires a general anesthesia, an expert operator and a trained nursing team, ESD instruments, carbone dioxide insufflation.",[13],[27],{"type":28,"name":29,"description":30,"armGroupLabels":31,"otherNames":10},"PROCEDURE","Polypectomy or myotomy","Advanced therapeutic endoscopy can replace surgery for treatment of benign and malign GI diseases and the aim of this registry-based study to improve quality related to advanced therapeutic endoscopy because the trial will provides a quantitative method to assess advanced therapeutic practise at the CHUM and may identify practices of low quality (possible intervention) or high quality (desired). Advanced therapeutic endoscopy procedures included for this registry-based study are EMR, ESD, Assessment of polypectomy quality for colorectal adenomas\u002Fpolyps, Radio Frequency Ablation (RFA) and Argon Plasma Ablation (APC), and Per Oral endoscopic Myotomy (POEM).",[15,9,23,19],[33],{"name":34,"affiliation":35,"role":36},"Daniel von Renteln, MD,PhD","Centre Hospitalier Universitaire de Montréal (CHUM)","PRINCIPAL_INVESTIGATOR",[38,43],{"name":39,"role":40,"phone":41,"phoneExt":10,"email":42},"Daniel von Renteln, MD, PhD","CONTACT","514-890-8000","daniel.von.renteln.med@ssss.gouv.qc.ca",{"name":44,"role":40,"phone":41,"phoneExt":45,"email":46},"Samira Hanin","30916","samira.hanin.chum@ssss.gouv.qc.ca",[48],{"facility":35,"status":49,"city":50,"state":51,"zip":10,"country":52,"countryCode":53,"cosmosGeoPoint":54,"geoPoint":59,"contacts":60},"RECRUITING","Montreal","Quebec","Canada","CA",{"type":55,"coordinates":56},"Point",[57,58],-73.58781,45.50884,{"lat":58,"lon":57},[61,63,64],{"name":39,"role":40,"phone":41,"phoneExt":62,"email":42},"30655",{"name":44,"role":40,"phone":41,"phoneExt":45,"email":46},{"name":65,"role":36,"phone":10,"phoneExt":10,"email":10},"Daniel von Renteln, MD",{"type":36,"investigatorFullName":67,"investigatorTitle":68,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"Daniel Von Renteln","Gastroenterologist, Principal Scientist, MD, PhD","100371494","advanced-endo-therapeutic-procedure--registry-based-observational-study-100371494",false,"NCT04117100","Advanced Endo-therapeutic Procedure : Registry-based Observational Study","AE Registry","Inclusion Criteria:\n\n* Age \\>18 years\n* Presenting for an elective advanced therapeutic endoscopy (ESD, EMR, advanced polypectomy, POEM or Zenker treatment)\n* Signed informed consent form\n\nExclusion Criteria:\n\n* Patients that are not capable understanding the trial and patients without consent.\n* Patients with coagulopathy\n* Patient with poor general health defined as an American Society of Anesthesiologists class greater than three\n* Pregnancy","ALL","18 Years",{"count":79,"type":80},500,"ESTIMATED","20 Years","OBSERVATIONAL","Advanced therapeutic endoscopy procedures are of increasing importance to provide minimal invasive treatment for GI diseases. The Centre Hospitalier de l'Université de Montréal as tertiary university center is dedicated to increase the availability of therapeutic endoscopy procedures for our population in Montreal and Quebec. Advanced endotherapeutic endoscopy can replace surgery for treatment of benign and malign GI diseases and the aim of this registry-based study is to improve quality related to advanced endotherapeutic endoscopy, as it will provide quantitative means to assess advanced endotherapeutic practice and may identify practices of low quality (possible intervention) or high quality (desired).",[85,86,87],"Zenker Diverticulum","Polyp of Colon","Colo-rectal Cancer","2025-02-28",{"date":90,"type":91},"2025-03-05","ACTUAL",{"date":93,"type":91},"2018-06-01",{"date":95,"type":80},"2025-12-31",{"name":5,"class":6},1]