[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100600931":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":11,"centralContacts":27,"locations":33,"responsibleParty":53,"collaborators":11,"id":55,"slug":56,"hasResults":57,"nctId":58,"briefTitle":59,"officialTitle":60,"acronym":11,"eligibilityCriteria":61,"healthyVolunteers":57,"sex":62,"minAge":63,"maxAge":64,"enrollmentInfo":65,"targetDuration":11,"studyType":68,"phases":69,"briefSummary":71,"conditions":72,"keywords":74,"overallStatus":36,"whyStopped":11,"lastUpdateSubmitDate":78,"lastUpdatePostDateStruct":79,"startDateStruct":82,"completionDateStruct":84,"leadSponsor":86,"locationsCount":87},{"fullName":5,"class":6},"Yale University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Moderate-Intensity Exercise","EXPERIMENTAL",null,[13],"Behavioral: Moderate-Intensity Exercise",{"label":15,"type":6,"description":16,"interventionNames":17},"Low-Intensity Exercise","Control",[18],"Behavioral: Low-Intensity Exercise",[20,24],{"type":21,"name":9,"description":22,"armGroupLabels":23,"otherNames":11},"BEHAVIORAL","Participants will engage in 20 minutes of cycling at approximately 70% max heart rate with a 2.5 minute warm up and a 2.5 minute cool down.",[9],{"type":21,"name":15,"description":25,"armGroupLabels":26,"otherNames":11},"Participants will engage in 20 minutes of cycling at approximately 40-50% max heart rate with a 2.5 minute warm up and a 2.5 minute cool down.",[15],[28],{"name":29,"role":30,"phone":31,"phoneExt":11,"email":32},"Emily Weiss, PhD","CONTACT","203-858-1225","emily.weiss@yale.edu",[34],{"facility":35,"status":36,"city":37,"state":38,"zip":39,"country":40,"countryCode":41,"cosmosGeoPoint":42,"geoPoint":47,"contacts":48},"Temple Medical Center","RECRUITING","New Haven","Connecticut","06511","United States","US",{"type":43,"coordinates":44},"Point",[45,46],-72.92816,41.30815,{"lat":46,"lon":45},[49,50],{"name":29,"role":30,"phone":11,"phoneExt":11,"email":32},{"name":51,"role":52,"phone":11,"phoneExt":11,"email":11},"Thomas Adams, PhD","PRINCIPAL_INVESTIGATOR",{"type":52,"investigatorFullName":51,"investigatorTitle":54,"investigatorAffiliation":5,"oldNameTitle":11,"oldOrganization":11},"Associate Professor","100600931","aerobic-exercise-and-obsessive-compulsive-disorder-symptoms-100600931",false,"NCT07103902","Aerobic Exercise and Obsessive-Compulsive Disorder Symptoms","Effects of Aerobic Exercise on Obsessive-Compulsive Disorder Symptoms and Cognitive Flexibility","Inclusion Criteria:\n\n* Adults, age 18 to 64 years\n* Meet diagnostic criteria for OCD (per the DIAMOND)\n* Stable psychiatric or medication treatment (if ≥4-weeks), or if no active treatment. Psychotropic medications will be reviewed with the study psychiatrist on a case by case basis.\n\nExclusion Criteria:\n\n* Active or unmanaged psychotic disorders, pervasive developmental disorders, bipolar disorder, current substance use disorder (moderate-to-severe), or high risk for suicide (defined as attempt, plan, or intent within past 3 months)\n* Documented motor impairments and medical condition(s) that prohibit physical exercise\n* Those who are pregnant or trying to become pregnant","ALL","18 Years","64 Years",{"count":66,"type":67},50,"ESTIMATED","INTERVENTIONAL",[70],"NA","The purpose of this study is to examine the acute effects of exercise on cognitive flexibility and symptom reactivity. The main questions it aims to answer are:\n\nDoes moderate intensity physical activity reduce subjective distress, compulsive urges, and intrusions- and increase cognitive flexibility- in adults with obsessive-compulsive disorder compared to low-intensity physical activity?\n\nResearchers will compare low- to moderate-intensity exercise to see if moderate physical activity increases cognitive flexibility and reduces symptom reactivity in adults with obsessive-compulsive disorder (OCD).\n\nParticipants will:\n\nComplete self-report surveys, psychiatric interviews, and cognitive tasks.\n\nBe assigned to either a low- or moderate-intensity exercise condition and complete physical activity.\n\nRepeat cognitive and symptom measures following the exercise intervention.",[73],"Obsessive-Compulsive Disorder (OCD)",[75,76,77],"Anxiety Disorders","Mental Disorders","Obsessive-Compulsive Disorder","2026-06-30",{"date":80,"type":81},"2026-07-02","ACTUAL",{"date":83,"type":81},"2026-02-16",{"date":85,"type":67},"2026-09-01",{"name":5,"class":6},1]