[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100624821":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":23,"centralContacts":28,"locations":39,"responsibleParty":54,"collaborators":23,"id":58,"slug":23,"hasResults":59,"nctId":60,"briefTitle":61,"officialTitle":62,"acronym":23,"eligibilityCriteria":63,"healthyVolunteers":59,"sex":64,"minAge":65,"maxAge":66,"enrollmentInfo":67,"targetDuration":23,"studyType":70,"phases":71,"briefSummary":73,"conditions":74,"keywords":77,"overallStatus":41,"whyStopped":23,"lastUpdateSubmitDate":83,"lastUpdatePostDateStruct":84,"startDateStruct":87,"completionDateStruct":89,"leadSponsor":91,"locationsCount":92},{"fullName":5,"class":6},"Bezmialem Vakif University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Complex Decongestive Physiotherapy (CDP)","EXPERIMENTAL","Participants will receive Complex Decongestive Physiotherapy (CDP) according to the standard clinical protocol.",[13],"Other: Complex Decongestive Physiotherapy (CDP)",{"label":15,"type":10,"description":16,"interventionNames":17},"CDP + Aerobic Exercise","Participants will receive Complex Decongestive Physiotherapy combined with a structured aerobic exercise program.",[13,18],"Other: Aerobic Training",[20,24],{"type":6,"name":9,"description":21,"armGroupLabels":22,"otherNames":23},"Participants will receive Complex Decongestive Physiotherapy five days per week for six weeks, including manual lymphatic drainage, compression bandaging, skin care, and therapeutic exercises.\n\nThe exercise program will consist of diaphragmatic breathing exercises, hip flexion-extension, hip abduction-adduction, knee flexion-extension (heel slides), ankle pumps, ankle circumduction, isometric quadriceps contractions, and isometric hip adduction.\n\nAll exercises will be performed in a slow and controlled manner under the supervision of a physiotherapist while compression bandaging is applied. Each exercise will be performed for 10 repetitions in one set during each treatment session.",[15,9],null,{"type":6,"name":25,"description":26,"armGroupLabels":27,"otherNames":23},"Aerobic Training","Participants will complete 20 minutes of aerobic training on a recumbent cycle ergometer. Training intensity will be prescribed at 40-59% of heart rate reserve, calculated using the Karvonen method. Each aerobic training session will conclude with a 5-minute cool-down period on the cycle ergometer at low intensity (≤40% of heart rate reserve).",[15],[29,35],{"name":30,"role":31,"phone":32,"phoneExt":33,"email":34},"Deniz Tuncer, PhD, PT","CONTACT","+902124012600","4647","dtuncer@bezmialem.edu.tr",{"name":36,"role":31,"phone":37,"phoneExt":23,"email":38},"Serra Undil-Erdogmus, PT","+90 541 214 15 43","serraundil@gmail.com",[40],{"facility":5,"status":41,"city":42,"state":23,"zip":23,"country":43,"countryCode":23,"cosmosGeoPoint":44,"geoPoint":49,"contacts":50},"RECRUITING","Istanbul","Turkey (Türkiye)",{"type":45,"coordinates":46},"Point",[47,48],28.94966,41.01384,{"lat":48,"lon":47},[51],{"name":52,"role":31,"phone":53,"phoneExt":23,"email":38},"Serra Undil, PT","+902125232288",{"type":55,"investigatorFullName":56,"investigatorTitle":57,"investigatorAffiliation":5,"oldNameTitle":23,"oldOrganization":23},"PRINCIPAL_INVESTIGATOR","Deniz Tuncer","Assistant Professor","100624821",false,"NCT07414615","Aerobic Training in Lower Extremity Lymphedema","The Effect of Aerobic Training on Gait, Postural Control, Lower Extremity Muscle Strength and Functionality in Patients With Lower Extremity Lymphedema","Inclusion Criteria:\n\n* Aged between 20 and 60 years\n* Diagnosed with bilateral lower extremity lymphedema\n* Completion of chemotherapy, radiotherapy, or other oncological treatments, with no oncological contraindication to participation\n* Signed written informed consent\n* Willingness to participate in the study\n\nExclusion Criteria:\n\n* Presence of uncontrolled cardiac or pulmonary disease\n* Presence of renal insufficiency\n* Presence of musculoskeletal or neurological disorders affecting mobility or balance\n* Presence of systemic or local infection in the lower extremity\n* Impaired independent ambulation or use of assistive walking devices\n* Pregnancy\n* Presence of visual, cognitive, or intellectual impairment that may interfere with participation in assessment or intervention procedures","ALL","20 Years","60 Years",{"count":68,"type":69},24,"ESTIMATED","INTERVENTIONAL",[72],"NA","This randomized controlled study aims to evaluate the effects of aerobic exercise training on gait, postural control, lower extremity muscle strength, and functional status in individuals with bilateral lower extremity lymphedema. A total of 24 participants aged between 20 and 60 years with a diagnosis of bilateral lower extremity lymphedema will be randomly assigned to either an aerobic exercise group or a control group. The aerobic exercise group will receive aerobic exercise training in addition to Complex Decongestive Therapy (CDT), while the control group will receive CDT alone.\n\nLower extremity edema will be assessed using circumferential measurements taken from the ankle to the inguinal region. Gait function will be evaluated through angular and spatiotemporal analysis using Kinovea software, including parameters such as step length, walking speed, and double support time. Postural control will be assessed using the Balance Error Scoring System (BESS) and the Timed Up and Go Test. Lower extremity muscle strength and endurance will be evaluated using Manual Muscle Testing and the 30-Second Sit-to-Stand Test. Functional status of the lower extremities will be assessed using the Lower Extremity Functional Scale (LEFS).",[75,76],"Lymphedema","Lymphedema Lower Extremity",[75,78,79,80,81,82],"Lower Extremity","Gait","Postural Control","Muscle Strength","Functionality","2026-02-17",{"date":85,"type":86},"2026-02-19","ACTUAL",{"date":88,"type":86},"2026-02-16",{"date":90,"type":69},"2026-04-10",{"name":5,"class":6},1]