[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100623143":3},{"organization":4,"armGroups":7,"interventions":13,"overallOfficials":19,"centralContacts":23,"locations":32,"responsibleParty":75,"collaborators":18,"id":77,"slug":78,"hasResults":79,"nctId":80,"briefTitle":81,"officialTitle":82,"acronym":83,"eligibilityCriteria":84,"healthyVolunteers":79,"sex":85,"minAge":18,"maxAge":18,"enrollmentInfo":86,"targetDuration":18,"studyType":89,"phases":90,"briefSummary":92,"conditions":93,"keywords":97,"overallStatus":105,"whyStopped":18,"lastUpdateSubmitDate":106,"lastUpdatePostDateStruct":107,"startDateStruct":110,"completionDateStruct":112,"leadSponsor":114,"locationsCount":115},{"fullName":5,"class":6},"University Hospital, Bordeaux","OTHER",[8],{"label":9,"type":6,"description":10,"interventionNames":11},"Patients starting long-term parenteral nutrition","Observational follow-up of patients starting long-term parenteral nutrition",[12],"Other: Non-invasive skin AGE measurements",[14],{"type":6,"name":15,"description":16,"armGroupLabels":17,"otherNames":18},"Non-invasive skin AGE measurements","Non-invasive skin AGE measurements at baseline, 6 and 12 months; collection and analysis of parenteral nutrition bag samples; routine metabolic assessments; dietary records, glucose holter, plasma glycated hemoglobin and fructosamine assays.",[9],null,[20],{"name":21,"affiliation":5,"role":22},"Florian POULLENOT, MD","PRINCIPAL_INVESTIGATOR",[24,28],{"name":21,"role":25,"phone":26,"phoneExt":18,"email":27},"CONTACT","+335 57 65 64 40","florian.poullenot@chu-bordeaux.fr",{"name":29,"role":25,"phone":30,"phoneExt":18,"email":31},"Raphaël ENAUD, MD","+335 56 79 98 24","raphael.enaud@chu-bordeaux.fr",[33,48,63],{"facility":34,"status":18,"city":35,"state":18,"zip":36,"country":37,"countryCode":38,"cosmosGeoPoint":39,"geoPoint":44,"contacts":45},"CHU de Bordeaux-Hôpital des enfants GH Pellegrin","Bordeaux","33076","France","FR",{"type":40,"coordinates":41},"Point",[42,43],-0.58046,44.84124,{"lat":43,"lon":42},[46,47],{"name":29,"role":25,"phone":30,"phoneExt":18,"email":31},{"name":29,"role":22,"phone":18,"phoneExt":18,"email":18},{"facility":49,"status":18,"city":50,"state":18,"zip":51,"country":37,"countryCode":38,"cosmosGeoPoint":52,"geoPoint":56,"contacts":57},"AP-HP - Hopital Robert Debré","Paris","75935",{"type":40,"coordinates":53},[54,55],2.3488,48.85341,{"lat":55,"lon":54},[58,62],{"name":59,"role":25,"phone":60,"phoneExt":18,"email":61},"Emmanuelle ECOCHARD-DUGELAY, MD","+331.87.89.16.46","emmanuelle.dugelay@aphp.fr",{"name":59,"role":22,"phone":18,"phoneExt":18,"email":18},{"facility":64,"status":18,"city":65,"state":18,"zip":66,"country":37,"countryCode":38,"cosmosGeoPoint":67,"geoPoint":71,"contacts":72},"CHU de Bordeaux - Hôpital Haut Lévêque","Pessac","33600",{"type":40,"coordinates":68},[69,70],-0.6324,44.80565,{"lat":70,"lon":69},[73,74],{"name":21,"role":25,"phone":26,"phoneExt":18,"email":27},{"name":21,"role":22,"phone":18,"phoneExt":18,"email":18},{"type":76,"investigatorFullName":18,"investigatorTitle":18,"investigatorAffiliation":18,"oldNameTitle":18,"oldOrganization":18},"SPONSOR","100623143","age-accumulation-in-patients-on-long-term-parenteral-nutrition-100623143",false,"NCT07392801","AGE Accumulation in Patients on Long-term Parenteral Nutrition","Study of Advanced Glycation End-products Accumulation in Patients Under Long-Term Parenteral Nutrition (NUPARAGE2)","NUPARAGE2","Inclusion Criteria:\n\n* Patients (adults and children, all ages) initiating long-term parenteral nutrition\n* Followed at CHU de Bordeaux or Robert Debré Hospital (APHP)\n* Covered by French Social Security system\n* Written informed consent obtained from patient (if adult) or legal guardian (if minor)\n\nExclusion Criteria:\n\n* Fitzpatrick skin type ≥ V (darker skin tones)\n* Forearm tattoos at the site of measurement\n* For patients included under 1 year of age: patients born prematurely (before 37 weeks of amenorrhea)\n* Pregnant or breastfeeding women.","ALL",{"count":87,"type":88},50,"ESTIMATED","INTERVENTIONAL",[91],"NA","This prospective and observational study aims to evaluate the accumulation of advanced glycation end-products (AGEs) in adult and pediatric patients starting long-term parenteral nutrition, by non-invasive skin AGE measurements over a 12-month follow-up.",[94,95,96],"Chronic Intestinal Insufficiency","Advanced Glycation and Products","Parenteral Nutrition",[98,99,100,101,102,103,104],"parenteral nutrition","Advanced Glycation End Products","Oxidative Stress","Metabolic Diseases","Cardiovascular Diseases","Short Bowel Syndrome","chronic intestinal insufficiency","NOT_YET_RECRUITING","2026-04-30",{"date":108,"type":109},"2026-05-06","ACTUAL",{"date":111,"type":88},"2026-05",{"date":113,"type":88},"2028-05",{"name":5,"class":6},3]