[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100617468":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":10,"centralContacts":12,"locations":19,"responsibleParty":36,"collaborators":10,"id":38,"slug":39,"hasResults":40,"nctId":41,"briefTitle":42,"officialTitle":43,"acronym":10,"eligibilityCriteria":44,"healthyVolunteers":40,"sex":45,"minAge":46,"maxAge":10,"enrollmentInfo":47,"targetDuration":10,"studyType":50,"phases":10,"briefSummary":51,"conditions":52,"keywords":57,"overallStatus":22,"whyStopped":10,"lastUpdateSubmitDate":72,"lastUpdatePostDateStruct":73,"startDateStruct":76,"completionDateStruct":78,"leadSponsor":80,"locationsCount":81},{"fullName":5,"class":6},"Hospital Universitari Vall d'Hebron Research Institute","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":10},"Acute stroke patients",null,"Single cohort of adults with suspected acute stroke (\\\u003C48 hours from symptom onset), including both ischaemic and intracerebral haemorrhagic stroke. All participants will undergo standard diagnostic evaluation with computed tomography (CT). A research transcranial Doppler ultrasound (TCD) examination will then be performed using a standardized acquisition protocol. Coded sonographic data will be used to train and evaluate artificial intelligence (AI) models for the classification of intracerebral haemorrhage (\"ICH suspected\" vs. \"No ICH\"). No intervention or change in clinical management is introduced as part of the study.",[13],{"name":14,"role":15,"phone":16,"phoneExt":17,"email":18},"RENATO SIMONETTI, MD","CONTACT","+34934893000","6660","renato.simonetti@vallhebron.cat",[20],{"facility":21,"status":22,"city":23,"state":24,"zip":25,"country":26,"countryCode":27,"cosmosGeoPoint":28,"geoPoint":33,"contacts":34},"Hospital Universitario Vall D'Hebron","RECRUITING","Barcelona","Catalonia","08035","Spain","ES",{"type":29,"coordinates":30},"Point",[31,32],2.15899,41.38879,{"lat":32,"lon":31},[35],{"name":14,"role":15,"phone":16,"phoneExt":17,"email":18},{"type":37,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR","100617468","ai-assisted-transcranial-duplex-sonography-for-early-detection-of-intracerebral-haemorrhage-hyper-ai-scan-100617468",false,"NCT07319013","AI-assisted Transcranial Duplex Sonography for Early Detection of Intracerebral Haemorrhage: HYPER-AI-SCAN","HYPER-AI-SCAN: HYPER-acute AI-assisted Sonographic Cerebral Hemorrhage Assessment Network","Inclusion Criteria:\n\n* Adult patients (age ≥18 years).\n* Clinical diagnosis of acute stroke (ischemic or intracerebral hemorrhage).\n* Able to undergo transtemporal transcranial ultrasound according to the standardized protocol (no clinical instability)\n* Informed consent obtained from the patient or legally authorized representative, per local regulations.\n\nExclusion Criteria:\n\n* Infratentorial hemorrhage (e.g., cerebellar or brainstem hemorrhage), due to limitations of transtemporal insonation.\n* Isolated subarachnoid hemorrhage without parenchymal involvement.\n* Hemodynamic instability or medical conditions requiring immediate life-saving intervention that preclude safe ultrasound recording.\n* Known skull defects or prior craniectomy on the side required for contralateral insonation.\n* Any condition that, in the opinion of the investigators, would interfere with protocol adherence or data accuracy.","ALL","18 Years",{"count":48,"type":49},500,"ESTIMATED","OBSERVATIONAL","The goal of this observational study is to evaluate whether transcranial Doppler ultrasound, combined with artificial intelligence (AI), can help identify intracerebral haemorrhage (ICH) in people with acute stroke (both men and women, adults of all ages) within 48 hours of symptom onset.\n\nThe main questions it aims to answer are:\n\nIs it feasible to perform standardized protocol transcranial ultrasound in acute stroke patients? Can AI models trained on ultrasound images accurately distinguish haemorrhagic stroke (\"ICH suspected\") from non-haemorrhagic stroke? There is no comparison group, because all participants will undergo both CT (as standard care) and ultrasound (research imaging), and the AI models will compare their ultrasound-based predictions against CT-confirmed diagnoses.\n\nParticipants will:\n\nundergo a non-invasive transcranial ultrasound scan after CT confirms the type of stroke allow researchers to collect coded ultrasound images for AI model training provide clinical and imaging information (already collected as part of routine care) to help evaluate factors related to diagnostic accuracy No treatments or changes to clinical care will be introduced as part of the study.",[53,54,55,56],"Stroke","Intracerebral Hemorrhage","Intracerebral Hemorrhage Basal Ganglia","Intracerebral Haemorrhage",[58,59,60,61,62,63,64,65,66,67,68,69,70,71],"stroke","intracerebral hemorrage","Ischemic Stroke","Hemorrhagic Stroke","transcranial ultrasound","Transcranial Doppler","Portable Ultrasound","Neurosonology","Artificial Intelligence","Machine Learning","Diagnostic Accuracy","Prehospital Care","Feasibility Study","Deep Learning","2025-12-19",{"date":74,"type":75},"2026-01-06","ACTUAL",{"date":77,"type":75},"2025-03-14",{"date":79,"type":49},"2027-06",{"name":5,"class":6},1]