[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100630696":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":33,"centralContacts":38,"locations":48,"responsibleParty":59,"collaborators":61,"id":75,"slug":76,"hasResults":77,"nctId":78,"briefTitle":79,"officialTitle":80,"acronym":43,"eligibilityCriteria":81,"healthyVolunteers":77,"sex":82,"minAge":83,"maxAge":43,"enrollmentInfo":84,"targetDuration":43,"studyType":87,"phases":88,"briefSummary":90,"conditions":91,"keywords":94,"overallStatus":102,"whyStopped":43,"lastUpdateSubmitDate":103,"lastUpdatePostDateStruct":104,"startDateStruct":107,"completionDateStruct":109,"leadSponsor":111,"locationsCount":112},{"fullName":5,"class":6},"NEUROPHET","INDUSTRY",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Experimental: AI-Based Customized tDCS","EXPERIMENTAL","Participants receive customized stimulation obtained from an individualized T1 MRI-based simulation of transcranial direct current stimulation for 30 minutes, once a day for 2 weeks, for a total of 10 sessions.",[13],"Device: AI-based Customized transcranial Direct Current Stimulation",{"label":15,"type":16,"description":17,"interventionNames":18},"Sham Comparator: sham tDCS","SHAM_COMPARATOR","Participants receive sham stimulation for 30 minutes once daily for 2 weeks (10 sessions total). Electrodes are placed according to the AI-based customized montage, but no current is delivered (0 mA).",[19],"Device: Sham transcranial Direct Current Stimulation",[21,28],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"DEVICE","AI-based Customized transcranial Direct Current Stimulation","Transcranial direct current stimulation (2 mA for 30 minutes) will be delivered using electrode positions optimized by an AI-based simulation based on each participant's MR images to target the motor cortex.",[9],[27],"NEUROPHET tES LAB, NEUROPHET innk01-DW",{"type":22,"name":29,"description":30,"armGroupLabels":31,"otherNames":32},"Sham transcranial Direct Current Stimulation","Transcranial direct current stimulation (0 mA for 30 minutes) will be delivered using electrode positions optimized by an AI-based simulation based on each participant's MR images.",[15],[27],[34],{"name":35,"affiliation":36,"role":37},"Deog Young Kim","Department and Research Institute of Rehabilitation Medicine, Yonsei University College of Medicine, Seoul, Republic of Korea","STUDY_CHAIR",[39,45],{"name":40,"role":41,"phone":42,"phoneExt":43,"email":44},"TaeYeong Kim","CONTACT","827051678882",null,"ty.kim@neurophet.com",{"name":46,"role":41,"phone":43,"phoneExt":43,"email":47},"Soo Young Whang","sywhang@neurophet.com",[49],{"facility":50,"status":43,"city":51,"state":43,"zip":43,"country":52,"countryCode":43,"cosmosGeoPoint":53,"geoPoint":58,"contacts":43},"Severance Hospital","Seoul","South Korea",{"type":54,"coordinates":55},"Point",[56,57],126.9784,37.566,{"lat":57,"lon":56},{"type":60,"investigatorFullName":43,"investigatorTitle":43,"investigatorAffiliation":43,"oldNameTitle":43,"oldOrganization":43},"SPONSOR",[62,64,66,68,70,73],{"name":50,"class":63},"OTHER",{"name":65,"class":63},"Asan Medical Center",{"name":67,"class":63},"Bucheon St. Mary's Hospital",{"name":69,"class":63},"Samsung Medical Center",{"name":71,"class":72},"National Rehabilitation Center, Seoul, Korea","OTHER_GOV",{"name":74,"class":63},"National Health Insurance Service Ilsan Hospital","100630696","ai-based-customized-tdcs-for-finger-motor-recovery-after-subacute-stroke-100630696",false,"NCT07491029","AI-based Customized tDCS for Finger Motor Recovery After Subacute Stroke","A Multi-center, Randomized, Double-blind, Prospective, Superiority Clinical Trial to Evaluate the Safety and Effectiveness of Artificial Intelligence-based Customized Transcranial Direct Current Stimulation Using MR Images for Improving Finger Motor Function in Patients With Finger Paralysis Due to Subacute Stroke","Inclusion Criteria:\n\nParticipants must meet all of the following criteria to be eligible for this clinical trial:\n\n1. Adults aged 19 years or older\n2. Patients with stroke confirmed by brain imaging\n3. Subacute stroke patients within 2 weeks to 3 months after stroke onset\n4. Patients with unilateral upper-extremity paralysis\n5. Upper-extremity Fugl-Meyer Assessment (FMA-UE, maximum score 66) score between 20 and 56\n6. Participants who voluntarily provide written informed consent after receiving and understanding the study procedures and requirements\n\nExclusion Criteria:\n\nParticipants will be excluded if they meet any of the following criteria:\n\n1. History of a condition affecting the function of the paralyzed arm\n2. Inability to follow instructions or complete the study due to cognitive impairment or aphasia\n3. Evidence of delirium, confusion, or other disorders of consciousness\n4. Presence of uncontrolled medical or surgical conditions\n5. Severe neurological disorders associated with major psychiatric conditions (e.g., major depressive disorder, schizophrenia, bipolar disorder, or dementia)\n6. History of uncontrolled epilepsy (seizure disorder)\n7. Contraindications to transcranial direct current stimulation (tDCS), including:\n\n   * Scalp disease or metal materials at the electrode attachment site\n   * Presence of a cardiac pacemaker or cochlear implant\n8. Medical contraindications to MRI examination\n9. Pregnant or breastfeeding women, or those planning pregnancy during the study period\n10. Use of a stimulation device similar to the investigational device or participation in a related clinical study within the past 1 year\n11. Individuals judged by the investigator to be medically or ethically unsuitable for participation in this clinical study","ALL","19 Years",{"count":85,"type":86},116,"ESTIMATED","INTERVENTIONAL",[89],"NA","The goal of this clinical study is to evaluate whether AI-based customized transcranial direct current stimulation (tDCS) using MR images is more effective than sham stimulation in improving finger motor function in patients with finger paralysis caused by subacute stroke. The main questions it aims to answer are:\n\n* Does AI-based customized tDCS improve finger motor function compared with sham stimulation?\n* What medical problems or adverse events occur when participants receive AI-based customized tDCS?\n\nResearchers will compare AI-based customized tDCS with sham stimulation (a look-alike stimulation that delivers no electrical current) to determine whether the intervention improves finger motor recovery in patients with subacute stroke.",[92,93],"Subacute Stroke","Upper Extremity Function",[95,96,97,98,99,100,101],"tDCS","stroke","rehabilitation","finger paralysis","upper extremity","transcranial direct current stimulation","upper limb motor function","NOT_YET_RECRUITING","2026-03-19",{"date":105,"type":106},"2026-03-24","ACTUAL",{"date":108,"type":86},"2026-04-30",{"date":110,"type":86},"2027-12-31",{"name":5,"class":6},1]