[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100621300":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":19,"centralContacts":20,"locations":26,"responsibleParty":44,"collaborators":19,"id":48,"slug":49,"hasResults":50,"nctId":51,"briefTitle":52,"officialTitle":53,"acronym":19,"eligibilityCriteria":54,"healthyVolunteers":50,"sex":55,"minAge":56,"maxAge":19,"enrollmentInfo":57,"targetDuration":19,"studyType":60,"phases":61,"briefSummary":63,"conditions":64,"keywords":68,"overallStatus":29,"whyStopped":19,"lastUpdateSubmitDate":72,"lastUpdatePostDateStruct":73,"startDateStruct":76,"completionDateStruct":78,"leadSponsor":80,"locationsCount":81},{"fullName":5,"class":6},"Ruijin Hospital","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Autonomous registration group","EXPERIMENTAL","All participants in this arm will undergo robotic navigational bronchoscopy and pulmonary nodule localization performed using the Langhe Bronchoscopy Robot System. The key intervention is the use of artificial intelligence (AI)-driven autonomous registration technology to automatically align the pre-operative chest CT images with the real-time bronchoscopic anatomy prior to the procedure. This process aims to reduce reliance on the conventional, operator-dependent manual registration. Physicians will supervise the entire process and perform necessary manual intervention if the AI registration is unsatisfactory or for safety reasons.",[13],"Device: AI-driven autonomous registration",[15],{"type":16,"name":17,"description":11,"armGroupLabels":18,"otherNames":19},"DEVICE","AI-driven autonomous registration",[9],null,[21],{"name":22,"role":23,"phone":24,"phoneExt":19,"email":25},"Hecheng Li, M.D., Ph.D.","CONTACT","+021 64370045","lihecheng2000@hotmail.com",[27],{"facility":28,"status":29,"city":30,"state":31,"zip":32,"country":33,"countryCode":34,"cosmosGeoPoint":35,"geoPoint":40,"contacts":41},"Ruijin Hospital Affiliated to Shanghai Jiao Tong University School of Medicine","RECRUITING","Shanghai","Shanghai Municipality","200025","China","CN",{"type":36,"coordinates":37},"Point",[38,39],121.45806,31.22222,{"lat":39,"lon":38},[42],{"name":43,"role":23,"phone":24,"phoneExt":19,"email":25},"Hecheng Li",{"type":45,"investigatorFullName":46,"investigatorTitle":47,"investigatorAffiliation":5,"oldNameTitle":19,"oldOrganization":19},"PRINCIPAL_INVESTIGATOR","Hecheng Li M.D., Ph.D","Director, Department of Thoracic Surgery, Ruijin Hospital","100621300","ai-driven-autonomous-registration-in-robotic-bronchoscopy-100621300",false,"NCT07368829","AI-Driven Autonomous Registration in Robotic Bronchoscopy","Feasibility and Safety of Artificial Intelligence-Driven Autonomous Registration in Robotic Navigational Bronchoscopy","Inclusion Criteria:\n\n* Age ≥ 18 years.\n* Radiologically confirmed pulmonary nodules requiring preoperative localization.\n* Scheduled for robotic navigational bronchoscopy using the Bronchoscopy Robot System.\n* Willing to provide written informed consent.\n\nExclusion Criteria:\n\n* Severe cardiopulmonary dysfunction (e.g., FEV1 \\\u003C 30% predicted).\n* Coagulopathy or anticoagulation therapy that cannot be safely interrupted.\n* Pregnancy or lactation.\n* Inability to tolerate bronchoscopy under general anesthesia.","ALL","18 Years",{"count":58,"type":59},20,"ESTIMATED","INTERVENTIONAL",[62],"NA","This study aims to evaluate the feasibility and safety of an artificial intelligence (AI)-driven autonomous registration technology in robotic navigational bronchoscopy. A total of 20 patients with pulmonary nodules requiring localization will be enrolled. The Langhe Bronchoscopy Robot System equipped with AI-based autonomous registration software will be used. Primary outcomes include the success rate of autonomous registration and the rate of manual intervention during the process. Secondary outcomes encompass registration time, complication rates, and nodule localization success.",[65,66,67],"Lung Nodules","Bronchoscopy","Localization Efficiency",[69,70,71],"Artificial Intelligence","Robotic Bronchoscopy","Pulmonary Nodule","2026-04-09",{"date":74,"type":75},"2026-04-13","ACTUAL",{"date":77,"type":75},"2026-03-01",{"date":79,"type":59},"2026-06-30",{"name":5,"class":6},1]