[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100580490":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":24,"centralContacts":28,"locations":34,"responsibleParty":68,"collaborators":24,"id":70,"slug":71,"hasResults":72,"nctId":73,"briefTitle":74,"officialTitle":75,"acronym":24,"eligibilityCriteria":76,"healthyVolunteers":72,"sex":77,"minAge":78,"maxAge":79,"enrollmentInfo":80,"targetDuration":24,"studyType":83,"phases":84,"briefSummary":86,"conditions":87,"keywords":89,"overallStatus":94,"whyStopped":24,"lastUpdateSubmitDate":95,"lastUpdatePostDateStruct":96,"startDateStruct":99,"completionDateStruct":101,"leadSponsor":103,"locationsCount":104},{"fullName":5,"class":6},"Union Hospital, Tongji Medical College, Huazhong University of Science and Technology","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"AI guided TIPS","EXPERIMENTAL","TIPS procedure will be conducted under the guidance of AI model",[13],"Other: AI guided TIPS",{"label":15,"type":16,"description":17,"interventionNames":18},"Artificially blinded TIPS","PLACEBO_COMPARATOR","TIPS will be conducted based on the experience of operators.",[19],"Other: Artificially blinded TIPS",[21,25],{"type":6,"name":9,"description":22,"armGroupLabels":23,"otherNames":24},"The TIPS procedure will be conducted under the guidance of AI model which was constructed based on the pre-operation enhanced CT images and intra-operation DSA images.",[9],null,{"type":6,"name":15,"description":26,"armGroupLabels":27,"otherNames":24},"The TIPS procedure will be conducted based on the experience of operators.",[15],[29],{"name":30,"role":31,"phone":32,"phoneExt":24,"email":33},"Lei Chen","CONTACT","+8615971480677","chan0812@126.com",[35,53,63],{"facility":36,"status":24,"city":37,"state":38,"zip":39,"country":40,"countryCode":41,"cosmosGeoPoint":42,"geoPoint":47,"contacts":48},"Wuhan Union Hospital","Wuhan","Hubei","430022","China","CN",{"type":43,"coordinates":44},"Point",[45,46],114.26667,30.58333,{"lat":46,"lon":45},[49],{"name":50,"role":31,"phone":51,"phoneExt":24,"email":52},"Chuansheng Zheng","13329702158","hqzcsxh@sina.com",{"facility":54,"status":24,"city":37,"state":38,"zip":39,"country":40,"countryCode":41,"cosmosGeoPoint":55,"geoPoint":57,"contacts":58},"Wuhan Union Jinyinhu Hospital",{"type":43,"coordinates":56},[45,46],{"lat":46,"lon":45},[59],{"name":60,"role":31,"phone":61,"phoneExt":24,"email":62},"Huangxuan Zhao, PhD","18971676985","zhao_huangxuan@sina.com",{"facility":64,"status":24,"city":37,"state":38,"zip":39,"country":40,"countryCode":41,"cosmosGeoPoint":65,"geoPoint":67,"contacts":24},"Wuhan Union West Hospital",{"type":43,"coordinates":66},[45,46],{"lat":46,"lon":45},{"type":69,"investigatorFullName":24,"investigatorTitle":24,"investigatorAffiliation":24,"oldNameTitle":24,"oldOrganization":24},"SPONSOR","100580490","ai-guided-tips-procedure-100580490",false,"NCT06837974","AI-guided TIPS Procedure","Construction and Application of an AI Model for Guided TIPS Surgical Puncture: a Prospective Multicenter Randomized Controlled Trial","Inclusion Criteria:\n\n* Participants who require transjugular intrahepatic portosystemic shunt (TIPS) and meet the clinical indications for the procedure.\n* Participants whose physical condition is suitable for TIPS.\n\nExclusion Criteria:\n\n* Participants with a history of allergy or serious adverse reactions to iodine contrast media or other related drugs.\n* Participants are pregnant or breastfeeding.\n* Participants are unwilling or unable to sign informed consent.","ALL","18 Years","80 Years",{"count":81,"type":82},180,"ESTIMATED","INTERVENTIONAL",[85],"NA","The goal of this clinical trial is to learn if transjugular intrahepatic portosystemic shunt (TIPS)-guided AI model can guide TIPS procedure in adults better than conventional TIPS procedure (artificially blinded TIPS). TIPS surgical outcomes and intraoperative and postoperative complications will also be observed. The main questions it aims to answer are:\n\n* Does the AI model lower the number of punctures, radiation dose, and complications of participants undergo TIPS?\n* Does the AI model improve the efficacy of TIPS for participants?\n\nParticipants will:\n\n* Take the TIPS by the guidance of the AI model or conventional manually blinded penetration (placebo)\n* The number of punctures, the success rate of the procedure, the radiation dose, intraoperative complications and postoperative complications within 3 months will be recorded\n* Intraoperative portal pressure gradient drop values, symptoms of ascites and rebleeding within 3 months after TIPS will be reported",[88],"Portal Hypertension Related to Cirrhosis",[90,91,92,93],"TIPS","AI","Efficacy","Complications","NOT_YET_RECRUITING","2025-02-16",{"date":97,"type":98},"2025-02-20","ACTUAL",{"date":100,"type":82},"2025-07-01",{"date":102,"type":82},"2026-10-31",{"name":5,"class":6},3]