[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100518800":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":20,"centralContacts":25,"locations":31,"responsibleParty":257,"collaborators":261,"id":286,"slug":287,"hasResults":288,"nctId":289,"briefTitle":290,"officialTitle":291,"acronym":10,"eligibilityCriteria":292,"healthyVolunteers":288,"sex":293,"minAge":294,"maxAge":10,"enrollmentInfo":295,"targetDuration":10,"studyType":298,"phases":10,"briefSummary":299,"conditions":300,"keywords":304,"overallStatus":57,"whyStopped":10,"lastUpdateSubmitDate":309,"lastUpdatePostDateStruct":310,"startDateStruct":313,"completionDateStruct":315,"leadSponsor":317,"locationsCount":318},{"fullName":5,"class":6},"Chinese Academy of Sciences","OTHER_GOV",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Gastric Cancer Patients Undergoing Neoadjuvant Chemotherapy",null,"This group comprises participants diagnosed with advanced gastric cancer. The participants will be treated with standard neoadjuvant chemotherapy regimens recommended by clinical guidelines. Treatment details, including the generic name of the drugs, dosage form, dosage, frequency, and duration, will be recorded according to the specific regimen.",[13],"Drug: Neoadjuvant Chemotherapy",[15],{"type":16,"name":17,"description":18,"armGroupLabels":19,"otherNames":10},"DRUG","Neoadjuvant Chemotherapy","Participants in this group are diagnosed with gastric cancer and are scheduled to undergo neoadjuvant chemotherapy as a part of their treatment regimen. The specific chemotherapy drugs, dosages, and schedules will be determined according to established clinical guidelines and the participant's specific condition.",[9],[21],{"name":22,"affiliation":23,"role":24},"Yali Zang, Ph.D.","Institute of Automation, Chinese Academy of Sciences","STUDY_DIRECTOR",[26],{"name":27,"role":28,"phone":29,"phoneExt":10,"email":30},"Di Dong, Ph.D.","CONTACT","+86 13811833760","di.dong@ia.ac.cn",[32,47,55,64,72,83,94,102,113,121,129,137,148,159,170,181,192,203,214,225,233,244],{"facility":33,"status":34,"city":35,"state":10,"zip":10,"country":36,"countryCode":37,"cosmosGeoPoint":38,"geoPoint":43,"contacts":44},"Cancer Institute and Hospital, Chinese Academy of Medical Sciences","NOT_YET_RECRUITING","Beijing","China","CN",{"type":39,"coordinates":40},"Point",[41,42],116.39723,39.9075,{"lat":42,"lon":41},[45],{"name":46,"role":28,"phone":10,"phoneExt":10,"email":10},"Xinming Zhao",{"facility":48,"status":34,"city":35,"state":10,"zip":10,"country":36,"countryCode":37,"cosmosGeoPoint":49,"geoPoint":51,"contacts":52},"Peking Union Medical College Hospital",{"type":39,"coordinates":50},[41,42],{"lat":42,"lon":41},[53],{"name":54,"role":28,"phone":10,"phoneExt":10,"email":10},"Zhenyu Jin",{"facility":56,"status":57,"city":35,"state":10,"zip":10,"country":36,"countryCode":37,"cosmosGeoPoint":58,"geoPoint":60,"contacts":61},"Peking University Cancer Hospital & Institute","RECRUITING",{"type":39,"coordinates":59},[41,42],{"lat":42,"lon":41},[62],{"name":63,"role":28,"phone":10,"phoneExt":10,"email":10},"Lei Tang",{"facility":65,"status":34,"city":35,"state":10,"zip":10,"country":36,"countryCode":37,"cosmosGeoPoint":66,"geoPoint":68,"contacts":69},"Peking University People's Hospital",{"type":39,"coordinates":67},[41,42],{"lat":42,"lon":41},[70],{"name":71,"role":28,"phone":10,"phoneExt":10,"email":10},"Yi Wang",{"facility":73,"status":34,"city":74,"state":10,"zip":10,"country":36,"countryCode":37,"cosmosGeoPoint":75,"geoPoint":79,"contacts":80},"Xiangya Hospital of Central South University","Changsha",{"type":39,"coordinates":76},[77,78],112.97087,28.19874,{"lat":78,"lon":77},[81],{"name":82,"role":28,"phone":10,"phoneExt":10,"email":10},"Weihua Liao",{"facility":84,"status":34,"city":85,"state":10,"zip":10,"country":36,"countryCode":37,"cosmosGeoPoint":86,"geoPoint":90,"contacts":91},"Fujian Cancer Hospital","Fuzhou",{"type":39,"coordinates":87},[88,89],119.30611,26.06139,{"lat":89,"lon":88},[92],{"name":93,"role":28,"phone":10,"phoneExt":10,"email":10},"Yangming Li",{"facility":95,"status":57,"city":85,"state":10,"zip":10,"country":36,"countryCode":37,"cosmosGeoPoint":96,"geoPoint":98,"contacts":99},"Fujian Medical University Union Hospital",{"type":39,"coordinates":97},[88,89],{"lat":89,"lon":88},[100],{"name":101,"role":28,"phone":10,"phoneExt":10,"email":10},"Changming Huang",{"facility":103,"status":34,"city":104,"state":10,"zip":10,"country":36,"countryCode":37,"cosmosGeoPoint":105,"geoPoint":109,"contacts":110},"Affiliated Cancer Hospital & Institute of Guangzhou Medical University","Guangzhou",{"type":39,"coordinates":106},[107,108],113.25,23.11667,{"lat":108,"lon":107},[111],{"name":112,"role":28,"phone":10,"phoneExt":10,"email":10},"Shuzhong Cui",{"facility":114,"status":34,"city":104,"state":10,"zip":10,"country":36,"countryCode":37,"cosmosGeoPoint":115,"geoPoint":117,"contacts":118},"First Affiliated Hospital, Sun Yat-Sen University",{"type":39,"coordinates":116},[107,108],{"lat":108,"lon":107},[119],{"name":120,"role":28,"phone":10,"phoneExt":10,"email":10},"Shenping Yu",{"facility":122,"status":34,"city":104,"state":10,"zip":10,"country":36,"countryCode":37,"cosmosGeoPoint":123,"geoPoint":125,"contacts":126},"Nanfang Hospital of Southern Medical University",{"type":39,"coordinates":124},[107,108],{"lat":108,"lon":107},[127],{"name":128,"role":28,"phone":10,"phoneExt":10,"email":10},"Guoxin Li",{"facility":130,"status":57,"city":104,"state":10,"zip":10,"country":36,"countryCode":37,"cosmosGeoPoint":131,"geoPoint":133,"contacts":134},"Sixth Affiliated Hospital, Sun Yat-sen University",{"type":39,"coordinates":132},[107,108],{"lat":108,"lon":107},[135],{"name":136,"role":28,"phone":10,"phoneExt":10,"email":10},"Xiaochun Meng",{"facility":138,"status":57,"city":139,"state":10,"zip":10,"country":36,"countryCode":37,"cosmosGeoPoint":140,"geoPoint":144,"contacts":145},"Yunnan Cancer Hospital","Kunming",{"type":39,"coordinates":141},[142,143],102.71833,25.03889,{"lat":143,"lon":142},[146],{"name":147,"role":28,"phone":10,"phoneExt":10,"email":10},"Zhenhui Li",{"facility":149,"status":34,"city":150,"state":10,"zip":10,"country":36,"countryCode":37,"cosmosGeoPoint":151,"geoPoint":155,"contacts":156},"Cancer Hospital of Guangxi Medical University","Nanning",{"type":39,"coordinates":152},[153,154],108.31667,22.81667,{"lat":154,"lon":153},[157],{"name":158,"role":28,"phone":10,"phoneExt":10,"email":10},"Guanqiao Jin",{"facility":160,"status":34,"city":161,"state":10,"zip":10,"country":36,"countryCode":37,"cosmosGeoPoint":162,"geoPoint":166,"contacts":167},"The Affiliated Hospital of Qingdao University","Qingdao",{"type":39,"coordinates":163},[164,165],120.38042,36.06488,{"lat":165,"lon":164},[168],{"name":169,"role":28,"phone":10,"phoneExt":10,"email":10},"Hexiang Wang",{"facility":171,"status":34,"city":172,"state":10,"zip":10,"country":36,"countryCode":37,"cosmosGeoPoint":173,"geoPoint":177,"contacts":178},"Ruijin Hospital","Shanghai",{"type":39,"coordinates":174},[175,176],121.45806,31.22222,{"lat":176,"lon":175},[179],{"name":180,"role":28,"phone":10,"phoneExt":10,"email":10},"Jun Zhang",{"facility":182,"status":34,"city":183,"state":10,"zip":10,"country":36,"countryCode":37,"cosmosGeoPoint":184,"geoPoint":188,"contacts":189},"First Hospital of China Medical University","Shenyang",{"type":39,"coordinates":185},[186,187],123.43278,41.79222,{"lat":187,"lon":186},[190],{"name":191,"role":28,"phone":10,"phoneExt":10,"email":10},"Zhenning Wang",{"facility":193,"status":34,"city":194,"state":10,"zip":10,"country":36,"countryCode":37,"cosmosGeoPoint":195,"geoPoint":199,"contacts":200},"The First Affiliated Hospital of Soochow University","Suzhou",{"type":39,"coordinates":196},[197,198],120.59538,31.30408,{"lat":198,"lon":197},[201],{"name":202,"role":28,"phone":10,"phoneExt":10,"email":10},"Jie Bao",{"facility":204,"status":34,"city":205,"state":10,"zip":10,"country":36,"countryCode":37,"cosmosGeoPoint":206,"geoPoint":210,"contacts":211},"Tianjin Medical University Cancer Institute and Hospital","Tianjin",{"type":39,"coordinates":207},[208,209],117.17667,39.14222,{"lat":209,"lon":208},[212],{"name":213,"role":28,"phone":10,"phoneExt":10,"email":10},"Zhaoxiang Ye",{"facility":215,"status":57,"city":216,"state":10,"zip":10,"country":36,"countryCode":37,"cosmosGeoPoint":217,"geoPoint":221,"contacts":222},"Henan Cancer Hospital","Zhengzhou",{"type":39,"coordinates":218},[219,220],113.64861,34.75778,{"lat":220,"lon":219},[223],{"name":224,"role":28,"phone":10,"phoneExt":10,"email":10},"Jing Li",{"facility":226,"status":57,"city":216,"state":10,"zip":10,"country":36,"countryCode":37,"cosmosGeoPoint":227,"geoPoint":229,"contacts":230},"The First Affiliated Hospital of Zhengzhou University",{"type":39,"coordinates":228},[219,220],{"lat":220,"lon":219},[231],{"name":232,"role":28,"phone":10,"phoneExt":10,"email":10},"Jianbo Gao",{"facility":234,"status":57,"city":235,"state":10,"zip":10,"country":36,"countryCode":37,"cosmosGeoPoint":236,"geoPoint":240,"contacts":241},"Zhenjiang First People's Hospital","Zhenjiang",{"type":39,"coordinates":237},[238,239],119.45508,32.21086,{"lat":239,"lon":238},[242],{"name":243,"role":28,"phone":10,"phoneExt":10,"email":10},"Xiuhong Shan",{"facility":245,"status":57,"city":246,"state":10,"zip":10,"country":247,"countryCode":248,"cosmosGeoPoint":249,"geoPoint":253,"contacts":254},"San Raffaele University Hospital, Italy","Milan","Italy","IT",{"type":39,"coordinates":250},[251,252],9.18951,45.46427,{"lat":252,"lon":251},[255],{"name":256,"role":28,"phone":10,"phoneExt":10,"email":10},"Francesco De Cobelli",{"type":258,"investigatorFullName":259,"investigatorTitle":260,"investigatorAffiliation":23,"oldNameTitle":10,"oldOrganization":10},"PRINCIPAL_INVESTIGATOR","Di Dong","Professor",[262,264,265,266,267,268,269,270,271,272,273,275,276,277,278,279,280,281,282,283,284,285],{"name":56,"class":263},"OTHER",{"name":33,"class":263},{"name":138,"class":263},{"name":215,"class":6},{"name":234,"class":263},{"name":182,"class":263},{"name":149,"class":263},{"name":65,"class":263},{"name":204,"class":263},{"name":226,"class":263},{"name":274,"class":263},"Nanfang Hospital, Southern Medical University",{"name":160,"class":263},{"name":171,"class":263},{"name":130,"class":263},{"name":48,"class":263},{"name":73,"class":263},{"name":103,"class":263},{"name":193,"class":263},{"name":114,"class":263},{"name":95,"class":263},{"name":84,"class":6},{"name":245,"class":263},"100518800","ai-prediction-of-gastric-cancer-response-to-neoadjuvant-chemotherapy-100518800",false,"NCT06035250","AI Prediction of Gastric Cancer Response to Neoadjuvant Chemotherapy","Deep Learning-Based Prediction of Gastric Cancer Response to Neoadjuvant Chemotherapy","Inclusion Criteria:\n\n* Age 18 years or older;\n* Pathologically diagnosed with advanced gastric cancer in accordance with the American AJCC's TNM staging standards;\n* Have not undergone any systematic anti-cancer treatments before neoadjuvant chemotherapy and have not had surgery for local progression or distant metastasis;\n* Received standard neoadjuvant chemotherapy as recommended by the clinical guidelines, and have documented treatment details;\n* CT imaging and biopsy pathology images strictly taken within one month prior to starting neoadjuvant treatment;\n* Patients possess comprehensive preoperative clinical information and post-operative TRG grading.\n\nExclusion Criteria:\n\n* Patients whose CT or pathology images are unclear, making lesion assessment infeasible;\n* Patients diagnosed with other concurrent tumors.","ALL","18 Years",{"count":296,"type":297},200,"ESTIMATED","OBSERVATIONAL","This study seeks to develop a deep-learning-based intelligent predictive model for the efficacy of neoadjuvant chemotherapy in gastric cancer patients. By utilizing the patients' CT imaging data, biopsy pathology images, and clinical information, the intelligent model will predict the post-neoadjuvant chemotherapy efficacy and prognosis, offering assistance in personalized treatment decisions for gastric cancer patients.",[301,302,303],"Gastric Cancer","Image","Pathology",[301,17,305,306,307,308],"Radiomics","Treatment Outcome Prediction","Pathomics","Radiopathomics","2023-09-26",{"date":311,"type":312},"2023-09-28","ACTUAL",{"date":314,"type":312},"2023-09-10",{"date":316,"type":297},"2029-12-31",{"name":5,"class":6},22]