[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100595593":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":31,"centralContacts":36,"locations":26,"responsibleParty":44,"collaborators":26,"id":46,"slug":47,"hasResults":48,"nctId":49,"briefTitle":50,"officialTitle":51,"acronym":52,"eligibilityCriteria":53,"healthyVolunteers":48,"sex":54,"minAge":55,"maxAge":26,"enrollmentInfo":56,"targetDuration":26,"studyType":59,"phases":60,"briefSummary":62,"conditions":63,"keywords":65,"overallStatus":68,"whyStopped":26,"lastUpdateSubmitDate":69,"lastUpdatePostDateStruct":70,"startDateStruct":73,"completionDateStruct":75,"leadSponsor":77,"locationsCount":26},{"fullName":5,"class":6},"Liverpool University Hospitals NHS Foundation Trust","OTHER_GOV",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Sterile air tamponade","EXPERIMENTAL","use of sterile air in place of fluorinated gases as a tamponade agent for rhegmatogenous retinal detachment vitrectomy surgery",[13],"Procedure: air",{"label":15,"type":16,"description":17,"interventionNames":18},"Fluorinated gas tamponade","ACTIVE_COMPARATOR","use of fluorinated gas (SF6, C2F6 or C3F8) as a tamponade agent for rhegmatogenous retinal detachment treated with vitrectomy",[19],"Procedure: Gas SF6 (Sulfur Hexafluoride) and others",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"PROCEDURE","air","use of sterile air as a tamponade",[9],null,{"type":22,"name":28,"description":29,"armGroupLabels":30,"otherNames":26},"Gas SF6 (Sulfur Hexafluoride) and others","use of fluorinated gases such as SF6, C2F6 or C3F8 as a tamponade agent",[15],[32],{"name":33,"affiliation":34,"role":35},"Rumana N Hussain, MBBS, FRCOph","Liverpool University Hospitals NHS Foundation Trust UK","PRINCIPAL_INVESTIGATOR",[37,41],{"name":33,"role":38,"phone":39,"phoneExt":26,"email":40},"CONTACT","01517063986","rumana.hussain@liverpoolft.nhs.uk",{"name":42,"role":38,"phone":26,"phoneExt":26,"email":43},"Darina Koneva","darina.koneva@liverpoolft.nhs.uk",{"type":45,"investigatorFullName":26,"investigatorTitle":26,"investigatorAffiliation":26,"oldNameTitle":26,"oldOrganization":26},"SPONSOR","100595593","air-tamponade-versus-fluorinated-gas-tamponade-for-rhegmatogenous-retinal-detachment-100595593",false,"NCT07034469","Air Tamponade Versus Fluorinated Gas Tamponade for Rhegmatogenous Retinal Detachment","Gas Tamponade Versus Air During Vitrectomy for Rhegmatogenous rEtinal dEtachmeNt; a Randomised Controlled Trial","GREEN","Inclusion Criteria:\n\n* Primary uncomplicated RRD undergoing vitrectomy.\n* Phakic and pseudophakic eyes\n* Retinal breaks superiorly between 3 and 9 o'clock, and that are separated by less than 4 clock hours.\n\nExclusion Criteria:\n\n* Absence of PVD\n* Age 40 years or younger\n* PVR grade C or above\n* Aphakia or anterior chamber lens\n* Retinal breaks greater than 1 clock hour in size\n* Retinal breaks that exist below 3 and 9 o'clock on both the nasal and temporal sides.\n* Retinal breaks at or posterior to the vessel arcades\n* Current or previous -6D myopia or greater (or axial length \\>26millimetres (mm))\n* Chronic RRD judged by the presence of subretinal bands and other signs of -chronicity or by history of visual loss for \\>28 days.\n* Significant inflammation, choroidal detachments, hypotony (\\\u003C6 millimetres of mercury (mmHg) preop)\n* Previous open-globe injury, or endophthalmitis\n* Current or previous posterior uveitis or choroiditis\n* Any intraocular surgical procedure within 4 weeks other than laser\u002Fcryotherapy\n* Any other condition that, in the opinion of the investigator, would prevent the participant from granting informed consent or complying with the protocol.","ALL","40 Years",{"count":57,"type":58},150,"ESTIMATED","INTERVENTIONAL",[61],"NA","TITLE: RCT of air tamponade versus fluorinated gas tamponade for rhegmatogenous retinal detachment DESIGN: Non-inferiority RCT of 150 patients from 10 UK centres AIMS: To assess whether air tamponade is non inferior to gas tamponade for the repair of RRD treated with vitrectomy.\n\nPRIMARY OUTCOME MEASURE: Primary anatomical success with single operation at 24 weeks.",[64],"Retinal Detachment Rhegmatogenous",[66,67,23],"retinal detachment","gas tamponade","NOT_YET_RECRUITING","2025-12-18",{"date":71,"type":72},"2025-12-24","ACTUAL",{"date":74,"type":58},"2026-03-20",{"date":76,"type":58},"2029-03-20",{"name":5,"class":6}]