[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100637850":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":26,"centralContacts":31,"locations":37,"responsibleParty":55,"collaborators":26,"id":59,"slug":60,"hasResults":61,"nctId":62,"briefTitle":63,"officialTitle":64,"acronym":65,"eligibilityCriteria":66,"healthyVolunteers":61,"sex":67,"minAge":68,"maxAge":26,"enrollmentInfo":69,"targetDuration":26,"studyType":72,"phases":73,"briefSummary":75,"conditions":76,"keywords":26,"overallStatus":78,"whyStopped":26,"lastUpdateSubmitDate":79,"lastUpdatePostDateStruct":80,"startDateStruct":83,"completionDateStruct":85,"leadSponsor":87,"locationsCount":88},{"fullName":5,"class":6},"Kantonsspital Baden","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Air Cystoscopy","EXPERIMENTAL","Flexible cystoscopy using air as the distension medium (up to 240 ml, manually administered via bladder syringe). This is the index cystoscopy for patients randomised to air.",[13],"Procedure: Air-based flexible cystoscopy",{"label":15,"type":16,"description":17,"interventionNames":18},"Saline Cystoscopy","ACTIVE_COMPARATOR","Flexible cystoscopy using 0.9% saline as the distension medium (up to 240 ml, manually administered via bladder syringe). Standard-of-care procedure. This is the index cystoscopy for patients randomised to saline.",[19],"Procedure: Saline-based flexible cystoscopy",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"PROCEDURE","Air-based flexible cystoscopy","Flexible cystoscopy with manual air insufflation (up to 240 ml) via bladder syringe for bladder distension and visualisation.",[9],null,{"type":22,"name":28,"description":29,"armGroupLabels":30,"otherNames":26},"Saline-based flexible cystoscopy","Flexible cystoscopy with manual saline irrigation (up to 240 ml, 0.9% NaCl) via bladder syringe for bladder distension and visualisation.",[15],[32],{"name":33,"role":34,"phone":35,"phoneExt":26,"email":36},"Lasse Petersen, Dr. med. univ.","CONTACT","+41 56 486 3083","lasse.petersen@ksb.ch",[38],{"facility":39,"status":26,"city":40,"state":41,"zip":42,"country":43,"countryCode":44,"cosmosGeoPoint":45,"geoPoint":50,"contacts":51},"Kantonsspital Baden AG, Department of Urology","Baden","Canton of Aargau","5404","Switzerland","CH",{"type":46,"coordinates":47},"Point",[48,49],8.30592,47.47333,{"lat":49,"lon":48},[52],{"name":53,"role":34,"phone":54,"phoneExt":26,"email":36},"Lasse Petersen, Dr.med. univ.","0041 56 486 3083",{"type":56,"investigatorFullName":57,"investigatorTitle":58,"investigatorAffiliation":5,"oldNameTitle":26,"oldOrganization":26},"PRINCIPAL_INVESTIGATOR","Lukas J Hefermehl","PD Dr. med.","100637850","air-vs-liquid-a-study-on-cystoscopy-performance-and-visibility-enhancement-in-macrohematuria-cases-100637850",false,"NCT07618221","Air vs. Liquid: A Study on Cystoscopy Performance and Visibility Enhancement in Macrohematuria Cases","AIROSCOPY - A Prospective, Randomized, Controlled, Single-Centre Superiority Study Comparing Air-Based Versus Saline-Based Flexible Cystoscopy for the Identification of the Bleeding Source in Patients With Macroscopic Haematuria","AIROSCOPY","Inclusion Criteria:\n\n* Persistent macroscopic haematuria Grade III-V within 48 hours after hospitalisation\n* Age ≥ 18 years\n* Unexplained macroscopic haematuria requiring diagnostic cystoscopy\n* Ability to give written informed consent\n\nExclusion Criteria:\n\n* Pregnant or lactating women\n* Haemodynamic instability or urgent need for operative or interventional cystoscopy (requiring cystoscopy within \\\u003C 24 hours of screening)\n* Ureteral stent in situ\n* Active urinary tract infection\n* Transurethral resection of the bladder (TURB) or prostate (TURP) within the last 6 weeks","ALL","18 Years",{"count":70,"type":71},40,"ESTIMATED","INTERVENTIONAL",[74],"NA","Macroscopic haematuria is a common urological emergency. Diagnostic cystoscopy is the gold standard for identifying the bleeding source; however, blood and clots within the bladder significantly impair endoscopic visibility when saline is used as the distension medium.\n\nAir-based cystoscopy, a technique first described in the 19th century, exploits the immiscibility of gas and blood to maintain clear visualisation even during active bleeding. Despite its theoretical advantages, no randomised clinical data exist to support its use.\n\nAIROSCOPY is a prospective, randomised, controlled, single-centre superiority study comparing air-based versus saline-based flexible cystoscopy in patients with macroscopic haematuria (Grade III-V). Patients are randomised 1:1. Only the index cystoscopy (first randomised modality) contributes to all study endpoints. A second cystoscopy with the alternative modality is performed solely for patient safety to ensure no diagnostic disadvantage from study participation. This second examination is not analysed.\n\nThe primary endpoint is identification of the bleeding source during the index cystoscopy (binary: yes\u002Fno). Secondary endpoints include time to source identification, total procedure duration, urologist-rated visibility (Likert scale), and patient comfort (Likert scale).",[77],"Macrohematuria","NOT_YET_RECRUITING","2026-05-31",{"date":81,"type":82},"2026-06-03","ACTUAL",{"date":84,"type":71},"2026-07-01",{"date":86,"type":71},"2028-06-01",{"name":5,"class":6},1]