[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100612580":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":12,"centralContacts":19,"locations":27,"responsibleParty":44,"collaborators":10,"id":46,"slug":47,"hasResults":48,"nctId":49,"briefTitle":50,"officialTitle":51,"acronym":10,"eligibilityCriteria":52,"healthyVolunteers":48,"sex":53,"minAge":10,"maxAge":54,"enrollmentInfo":55,"targetDuration":58,"studyType":59,"phases":10,"briefSummary":60,"conditions":61,"keywords":63,"overallStatus":30,"whyStopped":10,"lastUpdateSubmitDate":66,"lastUpdatePostDateStruct":67,"startDateStruct":70,"completionDateStruct":72,"leadSponsor":74,"locationsCount":75},{"fullName":5,"class":6},"University Hospital, Antwerp","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":10},"Participants with Protracted bacterial bronchitis diagnostic",null,"Children under five years old who attend pediatric outpatient visits or well-child visits at University Hospital Antwerp (UZA) and are diagnosed with Protracted bacterial bronchitis.",[13,16],{"name":14,"affiliation":5,"role":15},"Kim Van Hoorenbeeck, Prof. dr.","PRINCIPAL_INVESTIGATOR",{"name":17,"affiliation":18,"role":15},"Irina Spacova, Prof. dr. ir.","Universiteit Antwerpen",[20,24],{"name":14,"role":21,"phone":22,"phoneExt":10,"email":23},"CONTACT","+3238213000","kim.vanhoorenbeeck@uza.be",{"name":17,"role":21,"phone":25,"phoneExt":10,"email":26},"+3232653289","irina.spacova@uantwerpen.be",[28],{"facility":29,"status":30,"city":31,"state":10,"zip":32,"country":33,"countryCode":34,"cosmosGeoPoint":35,"geoPoint":40,"contacts":41},"Antwerp University Hospital","RECRUITING","Edegem","2650","Belgium","BE",{"type":36,"coordinates":37},"Point",[38,39],4.44504,51.15662,{"lat":39,"lon":38},[42,43],{"name":14,"role":21,"phone":22,"phoneExt":10,"email":23},{"name":14,"role":15,"phone":10,"phoneExt":10,"email":10},{"type":45,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR","100612580","airway-microbiome-of-patients-with-protracted-bacterial-bronchitis-100612580",false,"NCT07255430","Airway Microbiome of Patients With Protracted Bacterial Bronchitis","Interaction Between Microbiome, Virome and Host Immunity Response in the Context of Protracted Bacterial Bronchitis","Inclusion Criteria:\n\n* Children with PBB diagnosis according to case definition\n* Consent form signed by parents or legal guardians\n\nExclusion Criteria:\n\n* Comorbidities (HIV, asthma, chronic obstructive pulmonary disease, diabetes)\n* Have had serious illnesses (meningitis, pneumonia, bacteremia, empyema, etc) in the previous three months, identified only at the time of enrollment.\n* Have chronic respiratory conditions at the time of enrollment (non-PBB bronchiectasis not caused by PBB, CF, allergy, etc.).\n* Having received mechanical ventilation.\n* Having been hospitalized or used antibiotics in the previous three months at the time of enrollment.","ALL","5 Years",{"count":56,"type":57},160,"ESTIMATED","12 Months","OBSERVATIONAL","This project aims to assess the relationship between the microbiome and virome composition, the immune responses, and the respiratory health of children with protracted bacterial bronchitis (PBB). In addition, we aim to evaluate how the standard treatment with azithromycin interacts with the components of the microbiome, virome and immune biomarkers.",[62],"Protracted Bacterial Bronchitis",[64,62,65],"cough","microbiome","2026-03-18",{"date":68,"type":69},"2026-03-19","ACTUAL",{"date":71,"type":69},"2026-01-07",{"date":73,"type":57},"2029-01",{"name":5,"class":6},1]